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Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Youssef Sabiri , Walid Houmaidi , Amine Abouaomar

In this paper, a method is presented for superimposition (i.e. registration) of eye fundus images from persons with diabetes screened over many years for diabetic retinopathy. The method is fully automatic and robust to camera changes and…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Guillaume Noyel , Rebecca Thomas , Gavin Bhakta , Andrew Crowder , David Owens , Peter Boyle

Diabetic retinopathy is an eye-related pathology creating abnormalities and causing visual impairment, proper treatment of which requires identifying irregularities. This research uses a hemorrhage detection method and compares…

Image and Video Processing · Electrical Eng. & Systems 2022-06-03 Tamoor Aziz , Chalie Charoenlarpnopparut , Srijidtra Mahapakulchai

Purpose: Convolutional neural networks can be trained to detect various conditions or patient traits based on retinal fundus photographs, some of which, such as the patient sex, are invisible to the expert human eye. Here we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-01-18 Parsa Delavari , Gulcenur Ozturan , Ozgur Yilmaz , Ipek Oruc

Diabetic retinopathy is a leading cause of blindness in diabetic patients and early detection plays a crucial role in preventing vision loss. Traditional diagnostic methods are often time-consuming and prone to errors. The emergence of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Saif Ur Rehman Khan , Muhammad Nabeel Asim , Sebastian Vollmer , Andreas Dengel

Interpretability of deep learning (DL) systems is gaining attention in medical imaging to increase experts' trust in the obtained predictions and facilitate their integration in clinical settings. We propose a deep visualization method to…

Computer Vision and Pattern Recognition · Computer Science 2022-02-02 Cristina González-Gonzalo , Bart Liefers , Bram van Ginneken , Clara I. Sánchez

DRDr II is a hybrid of machine learning and deep learning worlds. It builds on the successes of its antecedent, namely, DRDr, that was trained to detect, locate, and create segmentation masks for two types of lesions (exudates and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Farzan Shenavarmasouleh , Farid Ghareh Mohammadi , M. Hadi Amini , Hamid R. Arabnia

Early detection of microaneurysms (MAs), the first sign of Diabetic Retinopathy (DR), is an essential first step in automated detection of DR to prevent vision loss and blindness. This study presents a novel and different algorithm for…

Retinal imaging has emerged as a powerful, non-invasive modality for detecting and quantifying biomarkers of systemic diseases-ranging from diabetes and hypertension to Alzheimer's disease and cardiovascular disorders but current insights…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Tariq M Khan , Toufique Ahmed Soomro , Imran Razzak

Reliable automatic diagnosis of Diabetic Retinopathy (DR) and Macular Edema (ME) is an invaluable asset in improving the rate of monitored patients among at-risk populations and in enabling earlier treatments before the pathology progresses…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Gabriel Lepetit-Aimon , Clément Playout , Marie Carole Boucher , Renaud Duval , Michael H Brent , Farida Cheriet

An overview of the applications of deep learning in ophthalmic diagnosis using retinal fundus images is presented. We also review various retinal image datasets that can be used for deep learning purposes. Applications of deep learning for…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sourya Sengupta , Amitojdeep Singh , Henry A. Leopold , Tanmay Gulati , Vasudevan Lakshminarayanan

Machine learning is gaining significant attention as a diagnostic tool in medical imaging, particularly in the analysis of retinal fundus images. However, this approach is not yet clinically applicable, as it still depends on human…

Human-Computer Interaction · Computer Science 2025-10-03 Mattea Reid , Zuhairah Zainal , Khaing Zin Than , Danielle Chan , Jonathan Chan

In this report, we applied integrated gradients to explaining a neural network for diabetic retinopathy detection. The integrated gradient is an attribution method which measures the contributions of input to the quantity of interest. We…

Artificial Intelligence · Computer Science 2017-10-19 Linyi Li , Matt Fredrikson , Shayak Sen , Anupam Datta

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

Machine Learning · Computer Science 2025-10-02 Mahyar Mahmoudi , Tieming Liu

In this work, we propose an AI-based method that intends to improve the conventional retinal disease treatment procedure and help ophthalmologists increase diagnosis efficiency and accuracy. The proposed method is composed of a deep neural…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Jia-Hong Huang , Chao-Han Huck Yang , Fangyu Liu , Meng Tian , Yi-Chieh Liu , Ting-Wei Wu , I-Hung Lin , Kang Wang , Hiromasa Morikawa , Hernghua Chang , Jesper Tegner , Marcel Worring

Diabetic retinopathy refers to the pathology of the retina induced by diabetes and is one of the leading causes of preventable blindness in the world. Early detection of diabetic retinopathy is critical to avoid vision problem through…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Malik A. Manan , Tariq M. Khan , Ahsan Saadat , Muhammad Arsalan , Syed S. Naqvi

Deep learning brought boosts to auto diabetic retinopathy (DR) diagnosis, thus, greatly helping ophthalmologists for early disease detection, which contributes to preventing disease deterioration that may eventually lead to blindness. It…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Xue Xia , Kun Zhan , Yuming Fang , Wenhui Jiang , Fei Shen

Refractive error, one of the leading cause of visual impairment, can be corrected by simple interventions like prescribing eyeglasses. We trained a deep learning algorithm to predict refractive error from the fundus photographs from…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Avinash V. Varadarajan , Ryan Poplin , Katy Blumer , Christof Angermueller , Joe Ledsam , Reena Chopra , Pearse A. Keane , Greg S. Corrado , Lily Peng , Dale R. Webster

Diabetic retinopathy is the leading cause of vision loss in working-age adults worldwide, yet under-resourced regions lack ophthalmologists. Current state-of-the-art deep learning systems struggle at these institutions due to limited…

Image and Video Processing · Electrical Eng. & Systems 2025-04-23 Gajan Mohan Raj , Michael G. Morley , Mohammad Eslami

The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed