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The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

Diferentially private (DP) synthetic datasets are a powerful approach for training machine learning models while respecting the privacy of individual data providers. The effect of DP on the fairness of the resulting trained models is not…

Machine Learning · Statistics 2021-06-21 Mayana Pereira , Meghana Kshirsagar , Sumit Mukherjee , Rahul Dodhia , Juan Lavista Ferres

While differentially private synthetic data generation has been explored extensively in the literature, how to update this data in the future if the underlying private data changes is much less understood. We propose an algorithmic…

Cryptography and Security · Computer Science 2024-09-04 Girish Kumar , Thomas Strohmer , Roman Vershynin

Synthetic clinical data are increasingly important for advancing AI in healthcare, given strict privacy constraints on real-world EHRs, limited availability of annotated rare-condition data, and systemic biases in observational datasets.…

Machine Learning · Computer Science 2025-09-16 Rumeng Li , Xun Wang , Hong Yu

Synthetic data generation has become essential for securely sharing and analyzing sensitive data sets. Traditional anonymization techniques, however, often fail to adequately preserve privacy. We introduce the Tabular Auto-Regressive…

Machine Learning · Computer Science 2025-08-12 Andrey Sidorenko , Paul Tiwald

Over the last three to five years, it has become possible to generate machine learning synthetic data for healthcare-related uses. However, concerns have been raised about potential negative factors associated with the possibilities of…

Synthetic data, which is artificially generated and intelligently mimicking or supplementing the real-world data, is increasingly used. The proliferation of AI agents and the adoption of synthetic data create a synthetic mirror that…

Computers and Society · Computer Science 2025-06-18 Marcelle Momha

Differential privacy has become a de facto standard for releasing data in a privacy-preserving way. Creating a differentially private algorithm is a process that often starts with a noise-free (non-private) algorithm. The designer then…

Cryptography and Security · Computer Science 2021-09-16 Yuxin Wang , Zeyu Ding , Yingtai Xiao , Daniel Kifer , Danfeng Zhang

Data privacy concerns have led to the growing interest in synthetic data, which strives to preserve the statistical properties of the original dataset while ensuring privacy by excluding real records. Recent advances in deep neural networks…

Methodology · Statistics 2025-07-15 Nir Keret , Ali Shojaie

In this work, we develop a privacy-by-design generative model for synthesizing the activity diary of the travel population using state-of-art deep learning approaches. This proposed approach extends literature on population synthesis by…

Machine Learning · Computer Science 2021-01-01 Godwin Badu-Marfo , Bilal Farooq , Zachary Patterson

Synthetic data generation is gaining traction as a privacy enhancing technology (PET). When properly generated, synthetic data preserve the analytic utility of real data while avoiding the retention of information that would allow the…

Generative Adversarial Networks (GANs) have shown considerable promise for mitigating the challenge of data scarcity when building machine learning-driven analysis algorithms. Specifically, a number of studies have shown that GAN-based…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Xiaodan Hu , Audrey G. Chung , Paul Fieguth , Farzad Khalvati , Masoom A. Haider , Alexander Wong

How to synthesize a dataset while achieving differential privacy for AI model training is a meaningful but challenging problem. To address this problem, state-of-the-art methods first select original private dataset's multiple…

Cryptography and Security · Computer Science 2026-04-20 Mingxuan Jia , Wen Huang , Weixin Zhao , Xingyi Wang , Jian Peng , Zhishuo Zhang

Recommendation systems make predictions chiefly based on users' historical interaction data (e.g., items previously clicked or purchased). There is a risk of privacy leakage when collecting the users' behavior data for building the…

Information Retrieval · Computer Science 2022-09-28 Fan Liu , Zhiyong Cheng , Huilin Chen , Yinwei Wei , Liqiang Nie , Mohan Kankanhalli

The success of deep learning is partly attributed to the availability of massive data downloaded freely from the Internet. However, it also means that users' private data may be collected by commercial organizations without consent and used…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Qi Tian , Kun Kuang , Kelu Jiang , Furui Liu , Zhihua Wang , Fei Wu

Artificial intelligence (AI) is increasingly used in every stage of drug development. Continuing breakthroughs in AI-based methods for drug discovery require the creation, improvement, and refinement of drug discovery data. We posit a new…

Machine Learning · Computer Science 2024-05-08 Bing Hu , Ashish Saragadam , Anita Layton , Helen Chen

Access to individual-level health data is essential for gaining new insights and advancing science. In particular, modern methods based on artificial intelligence rely on the availability of and access to large datasets. In the health…

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by grounding them in external knowledge. However, its application in sensitive domains is limited by privacy risks. Existing private RAG methods typically rely on…

Cryptography and Security · Computer Science 2026-05-13 Junki Mori , Kazuya Kakizaki , Taiki Miyagawa , Jun Sakuma

The utility of tabular data for tasks ranging from model training to large-scale data analysis is often constrained by privacy concerns or regulatory hurdles. While existing data generation methods, particularly those based on Generative…

Machine Learning · Computer Science 2025-10-29 Tu Anh Hoang Nguyen , Dang Nguyen , Tri-Nhan Vo , Thuc Duy Le , Sunil Gupta

Machine learning models have been criticized for reflecting unfair biases in the training data. Instead of solving for this by introducing fair learning algorithms directly, we focus on generating fair synthetic data, such that any…

Machine Learning · Computer Science 2021-11-08 Boris van Breugel , Trent Kyono , Jeroen Berrevoets , Mihaela van der Schaar
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