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A quasispecies is a set of interrelated genotypes that have reached a situation of equilibrium while evolving according to the usual Darwinian principles of selection and mutation. Quasispecies studies invariably assume that it is possible…

Populations and Evolution · Quantitative Biology 2012-08-21 Valmir C. Barbosa , Raul Donangelo , Sergio R. Souza

This contribution is concerned with mathematical models for the dynamics of the genetic composition of populations evolving under recombination. Recombination is the genetic mechanism by which two parent individuals create the mixed type of…

Populations and Evolution · Quantitative Biology 2011-01-12 Ellen Baake

In ecology and population dynamics, gene-flow refers to the transfer of a trait from one population to another. This phenomenon appears in studying the evolution of social features, such as languages. From the mathematical point of view,…

Optimization and Control · Mathematics 2021-10-22 Idriss Mazari , Domenec Ruiz-Balet , Enrique Zuazua

We introduce a generalization of the parallel, or Crow-Kimura, and Eigen models of molecular evolution to represent the exchange of genetic information between individuals in a population. We study the effect of different schemes of genetic…

Populations and Evolution · Quantitative Biology 2009-11-13 Enrique Munoz , Jeong-Man Park , Michael W. Deem

This is an introductory review of deterministic mutation-selection models for asexual populations (i.e., quasispecies theory) and related topics. First, the basic concepts of fitness, mutations, and sequence space are introduced. Different…

Populations and Evolution · Quantitative Biology 2007-07-26 Kavita Jain , Joachim Krug

This work addresses the problem of learning the dynamics of high-dimensional probability densities over time using unlabeled samples, without assuming access to trajectory information. We introduce two-parameter flows that learn only…

Machine Learning · Computer Science 2026-05-27 Paul Schwerdtner , Tobias Blickhan , Benjamin Peherstorfer

Normalizing flows are a powerful class of generative models for continuous random variables, showing both strong model flexibility and the potential for non-autoregressive generation. These benefits are also desired when modeling discrete…

Machine Learning · Statistics 2019-06-06 Zachary M. Ziegler , Alexander M. Rush

The recent interest in human dynamics has led researchers to investigate the stochastic processes that explain human behaviour in various contexts. Here we propose a generative model to capture the dynamics of survival analysis,…

Physics and Society · Physics 2015-09-30 Trevor Fenner , Mark Levene , George Loizou

We suggest a natural approach that leads to a modification of classical quasispecies models and incorporates the possibility of population extinction in addition to growth. The resulting modified models are called open. Their essential…

Populations and Evolution · Quantitative Biology 2019-03-25 Ivan Yegorov , Artem S. Novozhilov , Alexander S. Bratus

Self-organisation of individuals within large collectives occurs throughout biology. Mathematical models can help elucidate the individual-level mechanisms behind these dynamics, but analytical tractability often comes at the cost of…

The calibration of a reservoir model with observed transient data of fluid pressures and rates is a key task in obtaining a predictive model of the flow and transport behaviour of the earth's subsurface. The model calibration task, commonly…

Machine Learning · Computer Science 2019-06-13 Lukas Mosser , Olivier Dubrule , Martin J. Blunt

Reaction-diffusion equations describe various spatially extended processes that unfold as traveling fronts moving at constant velocity. We introduce and solve analytically a model that, besides such fronts, supports solutions advancing as…

Biological Physics · Physics 2026-02-13 Louis Brezin , Kyle J. Shaffer , Kirill S. Korolev

We study the adaptation dynamics of an initially maladapted population evolving via the elementary processes of mutation and selection. The evolution occurs on rugged fitness landscapes which are defined on the multi-dimensional genotypic…

Populations and Evolution · Quantitative Biology 2009-11-13 Kavita Jain

The basic mechanics of evolution have been understood since Darwin. But debate continues over whether macroevolutionary phenomena are driven primary by the fitness structure of genotype space or by ecological interaction. In this paper we…

Populations and Evolution · Quantitative Biology 2012-10-22 David V. Foster , Mary M. Rorick , Tanja Gesell , Laura Feeney , Jacob G. Foster

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó

Community assembly is studied using individual-based multispecies models. The models have stochastic population dynamics with mutation, migration, and extinction of species. Mutants appear as a result of mutation of the resident species,…

Populations and Evolution · Quantitative Biology 2010-05-18 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

This paper considers a nonlinear model for population dynamics with age structure. The fertility rate with respect to age is non constant and has the form proposed by [17]. Moreover, its multiplicative structure and the multiplicative…

General Mathematics · Mathematics 2023-12-06 Dragos-Patru Covei , Traian A. Pirvu , Catalin Sterbeti

Biological systems are modular, and this modularity evolves over time and in different environments. A number of observations have been made of increased modularity in biological systems under increased environmental pressure. We here…

Populations and Evolution · Quantitative Biology 2015-01-07 Jeong-Man Park , Liang Ren Niestemski , Michael W. Deem

Genetic variation in a population can sometimes arise so fast as to modify ecosystem dynamics. Such phenomena have been observed in natural predator-prey systems, and characterized in the laboratory as showing unusual phase relationships in…

Populations and Evolution · Quantitative Biology 2025-03-25 Hong-Yan Shih , Nigel Goldenfeld

Infinitely many distinct trait values may arise in populations bearing quantitative traits, and modeling their population dynamics is thus a formidable task. While classical models assume fixed or infinite population size, models in which…

Populations and Evolution · Quantitative Biology 2025-05-08 Ananda Shikhara Bhat