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The paper considers the problems of optimal vaccination control in the classical SIR model under constraints on the resource capabilities of the insurance medical system, in particular under constraints on the possible absolute rate of…

Optimization and Control · Mathematics 2025-11-24 Bogdan Norkin , Vladimir Norkin

Modelling epidemics via classical population-based models suffers from shortcomings that so-called individual-based models are able to overcome, as they are able to take heterogeneity features into account, such as super-spreaders, and…

Optimization and Control · Mathematics 2022-05-16 C. Courtès , E. Franck , K. Lutz , L. Navoret , Y. Privat

We apply optimal control theory to a generalized SEIR-type model. The proposed system has three controls, representing social distancing, preventive means, and treatment measures to combat the spread of the COVID-19 pandemic. We analyze…

Optimization and Control · Mathematics 2021-12-10 Mohamed Abdelaziz Zaitri , Mohand Ouamer Bibi , Delfim F. M. Torres

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

We propose a mathematical spatiotemporal epidemic SICA model with a control strategy. The spatial behavior is modeled by adding a diffusion term with the Laplace operator, which is justified and interpreted both mathematically and…

Optimization and Control · Mathematics 2022-07-12 Houssine Zine , Abderrahim El Adraoui , Delfim F. M. Torres

Accurate identification of effective epidemic threshold is essential for understanding epidemic dynamics on complex networks. The existing studies on the effective epidemic threshold of the susceptible-infected-removed (SIR) model generally…

Physics and Society · Physics 2016-06-14 Panpan Shu , Wei Wang , Ming Tang , Pengcheng Zhao , Yi-Cheng Zhang

We propose a dynamical model for describing the spread of epidemics. This model is an extension of the SIQR (susceptible-infected-quarantined-recovered) and SIRP (susceptible-infected-recovered-pathogen) models used earlier to describe…

Physics and Society · Physics 2022-12-08 S. P. Lukyanets , I. S. Gandzha , O. V. Kliushnichenko

This contribution mainly focuses on the finite horizon optimal control problems of a susceptible-infected-vaccinated(SIV) epidemic system governed by reaction-diffusion equations and Markov switching. Stochastic dynamic programming is…

Optimization and Control · Mathematics 2024-01-23 Zong Wang

We propose two SIR models which incorporate sociological behavior of groups of individuals. It is these differences in behaviors which impose different infection rates on the individual susceptible populations, rather than biological…

Dynamical Systems · Mathematics 2022-07-26 Robert F. Allen , Katherine Heller , Matthew A. Pons

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shortening the interaction time between susceptible and infected…

Populations and Evolution · Quantitative Biology 2016-12-28 Bin Wu , Shanjun Mao , Jiazeng Wang , Da Zhou

In the recent COVID-19 pandemic we assisted at a sequence of epidemic waves intertwined by anomalous fade-outs with periods of low but persistent epidemic prevalence. These long-living epidemic states complicate epidemic control and…

Physics and Society · Physics 2025-08-27 Javier Aguilar , Beatriz Arregui García , Raúl Toral , Sandro Meloni , Jose J. Ramasco

In this paper, we conduct mathematical and numerical analyses to address the following crucial questions for COVID-19: (Q1) Is it possible to contain COVID-19? (Q2) When will be the peak and the end of the epidemic? (Q3) How do the…

Populations and Evolution · Quantitative Biology 2020-09-22 Yi-Cheng Chen , Ping-En Lu , Cheng-Shang Chang , Tzu-Hsuan Liu

The spread of an epidemic process is considered in the context of a spatial SIR stochastic model that includes a parameter $0\le p\le 1$ that assigns weights $p$ and $1- p$ to global and local infective contacts respectively. The model was…

Populations and Evolution · Quantitative Biology 2020-01-29 Gabriel Fabricius , Alberto Maltz

This paper proposes a novel discrete-time multi-virus susceptible-infected-recovered (SIR) model that captures the spread of competing epidemics over a population network. First, we provide sufficient conditions for the infection level of…

Systems and Control · Electrical Eng. & Systems 2023-05-17 Ciyuan Zhang , Sebin Gracy , Tamer Basar , Philip E. Pare

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

We consider the spread of a supercritical stochastic SIR (Susceptible, Infectious, Recovered) epidemic on a configuration model random graph. We mainly focus on the final stages of a large outbreak and provide limit results for the duration…

Probability · Mathematics 2020-02-26 Abid Ali Lashari , Ana Serafimović , Pieter Trapman

We consider an epidemic process on adaptive activity-driven temporal networks, with adaptive behaviour modelled as a change in activity and attractiveness due to infection. By using a mean-field approach, we derive an analytical estimate of…

Physics and Society · Physics 2020-09-02 Marco Mancastroppa , Raffaella Burioni , Vittoria Colizza , Alessandro Vezzani

Imported COVID-19 cases, if unchecked, can jeopardize the effort of domestic containment. We aim to find out what sustainable border control options for different entities (e.g., countries, states) exist during the reopening phases, given…

Populations and Evolution · Quantitative Biology 2021-02-05 Zhen Zhu , Enzo Weber , Till Strohsal , Duaa Serhan

We have designed a computational model of a virus spread near the outbreak threshold. Using computer simulation we studied the Susceptible - Infected - Recovered (SIR) process where in consequence of a force of habit that is manifested by…

Populations and Evolution · Quantitative Biology 2021-12-23 Jozef Černák

One of the main challenges of the measures against the COVID-19 epidemic is to reduce the amplitude of the epidemic peak without increasing without control its timescale. We investigate this problem using the SIR model for the epidemic…

Populations and Evolution · Quantitative Biology 2020-07-15 Mariano Cadoni