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Without vaccines and treatments, societies must rely on non-pharmaceutical intervention strategies to control the spread of emerging diseases such as COVID-19. Though complete lockdown is epidemiologically effective, because it eliminates…

Populations and Evolution · Quantitative Biology 2021-01-08 Jason Hindes , Simone Bianco , Ira B. Schwartz

We study the impact of model parameter uncertainty on optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic model and consider testing for isolation as…

Systems and Control · Electrical Eng. & Systems 2022-09-07 Baike She , Shreyas Sundaram , Philip E. Paré

Pandemics involve the high transmission of a disease that impacts global and local health and economic patterns. The impact of a pandemic can be minimized by enforcing certain restrictions on a community. However, while minimizing infection…

Artificial Intelligence · Computer Science 2024-02-13 Ishir Rao

This paper presents a simple continuous-time linear vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

The rapid spread of the Coronavirus (COVID-19) confronts policy makers with the problem of measuring the effectiveness of containment strategies, balancing public health considerations with the economic costs of social distancing measures.…

Physics and Society · Physics 2021-04-02 Claudius Gros , Roser Valenti , Lukas Schneider , Kilian Valenti , Daniel Gros

In social networks, control of rumor spread is an active area of research. SIR model is generally used to study the rumor dynamics in network while considering the rumor as an epidemic. In disease spreading model, epidemic is controlled by…

Social and Information Networks · Computer Science 2015-09-29 Anoop Mehta , Ruchir Gupta

Networks of contacts capable of spreading infectious diseases are often observed to be highly heterogeneous, with the majority of individuals having fewer contacts than the mean, and a significant minority having relatively very many…

Physics and Society · Physics 2016-12-21 César Parra-Rojas , Thomas House , Alan J. McKane

This work will study an optimal control problem describing the two-strain SEIR epidemic model. The studied model is in the form of six nonlinear differential equations illustrating the dynamics of the susceptibles and the exposed, the…

Populations and Evolution · Quantitative Biology 2024-04-29 Karam Allali , Mouhamadou A. M. T. Balde , Babacar M. Ndiaye

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

This paper considers a stochastic SIR (susceptible$\to$infective$\to$removed) epidemic model in which individuals may make infectious contacts in two ways, both within `households' (which for ease of exposition are assumed to have equal…

Probability · Mathematics 2015-03-13 Frank Ball , David Sirl , Pieter Trapman

Nowadays, epidemic models provide an appropriate tool for describing the propagation of biological viruses in human or animal populations, or rumours and other kinds of information in social networks and malware in both computer and ad hoc…

Optimization and Control · Mathematics 2020-07-21 Vladislav Taynitskiy , Elena Gubar , Denis Fedyanin , Ilya Petrov , Quanyan Zhu

We consider the low-prevalence linearized SEIR epidemic model for a society that has resolved to keep future infections low in anticipation of a vaccine. The society can vary its amount of potentially-infection-spreading activity over time,…

Optimization and Control · Mathematics 2020-09-17 Scott Sheffield

Developing robust, quantitative methods to optimize resource allocations in response to epidemics has the potential to save lives and minimize health care costs. In this paper, we develop and apply a computationally efficient algorithm that…

Quantitative Methods · Quantitative Biology 2015-06-22 Edwin C. Yuan , David L. Alderson , Sean Stromberg , Jean M. Carlson

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

Populations and Evolution · Quantitative Biology 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino

This paper presents a discrete time probabilistic dynamic for simulating a contact-based epidemic spreading based on discrete time Markov chain process, in particular the attention is addressed to the susceptible-infectious-removed (SIR)…

Physics and Society · Physics 2017-12-22 Fabrizio Angaroni

In real social networks, person-to-person interactions are known to be heterogeneous, which can affect the way a disease spreads through a population, reaches a tipping point in the fraction of infected individuals, and becomes an epidemic.…

Physics and Society · Physics 2020-05-12 Ignacio A. Perez , Paul A. Trunfio , Cristian E. La Rocca , Lidia A. Braunstein

In this paper, we have studied epidemiological models for Ebola infection using nonlinear ordinary differential equations and optimal control theory. We considered optimal control analysis of SIR and SEIR models for the deadly Ebola…

Dynamical Systems · Mathematics 2019-08-23 E. Okyere , J. D. Ankamah , A. K. Hunkpe , D. Mensah

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

Populations and Evolution · Quantitative Biology 2016-03-29 Chantal Nguyen , Jean M. Carlson

The non-population conserving SIR (SIR-NC) model to describe the spread of infections in a community is proposed and studied. Unlike the standard SIR model, SIR-NC does not assume population conservation. Although similar in form to the…

Optimization and Control · Mathematics 2020-11-06 Vivek S. Borkar , D. Manjunath

In this paper, we study a novel control method for a generalized SIS epidemic process. In particular, we use predictive control to design optimal protective resource distribution strategies which balance the need to eliminate the epidemic…

Optimization and Control · Mathematics 2018-08-17 Nicholas J. Watkins , George J. Pappas
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