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We present a contrasting learning approach with data augmentation techniques to learn document representations in an unsupervised manner. Inspired by recent contrastive self-supervised learning algorithms used for image and NLP pretraining,…

Computation and Language · Computer Science 2021-03-29 Dongsheng Luo , Wei Cheng , Jingchao Ni , Wenchao Yu , Xuchao Zhang , Bo Zong , Yanchi Liu , Zhengzhang Chen , Dongjin Song , Haifeng Chen , Xiang Zhang

Predicting enzymatic reactions is crucial for applications in biocatalysis, metabolic engineering, and drug discovery, yet it remains a complex and resource-intensive task. Large Language Models (LLMs) have recently demonstrated remarkable…

Artificial Intelligence · Computer Science 2025-05-12 Lorenzo Di Fruscia , Jana Marie Weber

Selecting an appropriate response from many candidates given the utterances in a multi-turn dialogue is the key problem for a retrieval-based dialogue system. Existing work formalizes the task as matching between the utterances and a…

Computation and Language · Computer Science 2022-03-03 Wentao Zhang , Shuang Xu , Haoran Huang

Modern retrieval systems do not rely on a single ranking model to construct their rankings. Instead, they generally take a cascading approach where a sequence of ranking models are applied in multiple re-ranking stages. Thereby, they…

Information Retrieval · Computer Science 2025-04-17 Harrie Oosterhuis , Rolf Jagerman , Zhen Qin , Xuanhui Wang

Multi-contrast MRI acquisitions of an anatomy enrich the magnitude of information available for diagnosis. Yet, excessive scan times associated with additional contrasts may be a limiting factor. Two mainstream approaches for enhanced scan…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Salman Ul Hassan Dar , Mahmut Yurt , Mohammad Shahdloo , Muhammed Emrullah Ildız , Tolga Çukur

Aiming towards human-level generalization, there is a need to explore adaptable representation learning methods with greater transferability. Most existing approaches independently address task-transferability and cross-domain adaptation,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Jogendra Nath Kundu , Nishank Lakkakula , R. Venkatesh Babu

In recent years, a variety of contrastive learning based unsupervised visual representation learning methods have been designed and achieved great success in many visual tasks. Generally, these methods can be roughly classified into four…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Wenbin Li , Meihao Kong , Xuesong Yang , Lei Wang , Jing Huo , Yang Gao , Jiebo Luo

Medical images and reports offer invaluable insights into patient health. The heterogeneity and complexity of these data hinder effective analysis. To bridge this gap, we investigate contrastive learning models for cross-domain retrieval,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Demetrio Deanda , Yuktha Priya Masupalli , Jeong Yang , Young Lee , Zechun Cao , Gongbo Liang

As a successful approach to self-supervised learning, contrastive learning aims to learn invariant information shared among distortions of the input sample. While contrastive learning has yielded continuous advancements in sampling strategy…

Machine Learning · Computer Science 2023-08-11 Jiangmeng Li , Wenwen Qiang , Yanan Zhang , Wenyi Mo , Changwen Zheng , Bing Su , Hui Xiong

Multiview network embedding aims at projecting nodes in the network to low-dimensional vectors, while preserving their multiple relations and attribute information. Contrastive learning approaches have shown promising performance in this…

Machine Learning · Computer Science 2022-08-18 Mengqi Zhang , Yanqiao Zhu , Qiang Liu , Shu Wu , Liang Wang

Contrastive self-supervised learning (CSL) with a prototypical regularization has been introduced in learning meaningful representations for downstream tasks that require strong semantic information. However, to optimize CSL with a loss…

Computer Vision and Pattern Recognition · Computer Science 2022-10-20 Shentong Mo , Zhun Sun , Chao Li

In this paper, we propose the CodeRetriever model, which learns the function-level code semantic representations through large-scale code-text contrastive pre-training. We adopt two contrastive learning schemes in CodeRetriever: unimodal…

Computation and Language · Computer Science 2022-10-27 Xiaonan Li , Yeyun Gong , Yelong Shen , Xipeng Qiu , Hang Zhang , Bolun Yao , Weizhen Qi , Daxin Jiang , Weizhu Chen , Nan Duan

We propose a two-stage "Mine and Refine" contrastive training framework for semantic text embeddings to enhance multi-category e-commerce search retrieval. Large scale e-commerce search demands embeddings that generalize to long tail, noisy…

Information Retrieval · Computer Science 2026-02-20 Jiaqi Xi , Raghav Saboo , Luming Chen , Martin Wang , Sudeep Das

The popularity of self-supervised learning has made it possible to train models without relying on labeled data, which saves expensive annotation costs. However, most existing self-supervised contrastive learning methods often overlook the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Weiquan Li , Xianzhong Long , Yun Li

Motivation: High-throughput experimental techniques have been producing more and more protein-protein interaction (PPI) data. PPI network alignment greatly benefits the understanding of evolutionary relationship among species, helps…

Data Structures and Algorithms · Computer Science 2016-04-13 Somaye Hashemifar , Qixing Huang , Jinbo XU

Chromosome karyotype analysis is of great clinical importance in the diagnosis and treatment of diseases, especially for genetic diseases. Since manual analysis is highly time and effort consuming, computer-assisted automatic chromosome…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Liye Mei , Yalan Yu , Yueyun Weng , Xiaopeng Guo , Yan Liu , Du Wang , Sheng Liu , Fuling Zhou , Cheng Lei

Few-shot classification and meta-learning methods typically struggle to generalize across diverse domains, as most approaches focus on a single dataset, failing to transfer knowledge across various seen and unseen domains. Existing…

Machine Learning · Computer Science 2025-10-07 Kristi Topollai , Anna Choromanska

Deep learning-based drug response prediction (DRP) methods can accelerate the drug discovery process and reduce R\&D costs. Although the mainstream methods achieve high accuracy in predicting response regression values, the regression-aware…

Biomolecules · Quantitative Biology 2023-12-19 Kun Li , Wenbin Hu

Recent methods for deep metric learning have been focusing on designing different contrastive loss functions between positive and negative pairs of samples so that the learned feature embedding is able to pull positive samples of the same…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Shichao Kan , Zhiquan He , Yigang Cen , Yang Li , Vladimir Mladenovic , Zhihai He

Learning from 3D protein structures has gained wide interest in protein modeling and structural bioinformatics. Unfortunately, the number of available structures is orders of magnitude lower than the training data sizes commonly used in…

Biomolecules · Quantitative Biology 2022-06-01 Pedro Hermosilla , Timo Ropinski