English
Related papers

Related papers: Multi-Alignment Contrastive Learning for Enzyme--R…

200 papers

Enzymes are important proteins that catalyze chemical reactions. In recent years, machine learning methods have emerged to predict enzyme function from sequence; however, there are no standardized benchmarks to evaluate these methods. We…

Biomolecules · Quantitative Biology 2025-06-13 Jason Yang , Ariane Mora , Shengchao Liu , Bruce J. Wittmann , Anima Anandkumar , Frances H. Arnold , Yisong Yue

Contrastive Learning (CL) performances as a rising approach to address the challenge of sparse and noisy recommendation data. Although having achieved promising results, most existing CL methods only perform either hand-crafted data or…

Information Retrieval · Computer Science 2023-11-22 Xiuyuan Qin , Huanhuan Yuan , Pengpeng Zhao , Junhua Fang , Fuzhen Zhuang , Guanfeng Liu , Victor Sheng

Modality representation learning is an important problem for multimodal sentiment analysis (MSA), since the highly distinguishable representations can contribute to improving the analysis effect. Previous works of MSA have usually focused…

Multimedia · Computer Science 2023-01-31 Peipei Liu , Xin Zheng , Hong Li , Jie Liu , Yimo Ren , Hongsong Zhu , Limin Sun

Cross-modal retrieval is the task of retrieving samples of a given modality by using queries of a different one. Due to the wide range of practical applications, the problem has been mainly focused on the vision and language case, e.g. text…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Jorge Sánchez , Rodrigo Laguna

Unsupervised region representation learning aims to extract dense and effective features from unlabeled urban data. While some efforts have been made for solving this problem based on multiple views, existing methods are still insufficient…

Computer Vision and Pattern Recognition · Computer Science 2022-11-17 Liang Zhang , Cheng Long , Gao Cong

Contrastive learning has been successfully used for retrieval of semantically aligned sentences, but it often requires large batch sizes or careful engineering to work well. In this paper, we instead propose a generative model for learning…

Computation and Language · Computer Science 2023-06-06 John Wieting , Jonathan H. Clark , William W. Cohen , Graham Neubig , Taylor Berg-Kirkpatrick

Visual-language models (VLMs) excel at data mappings, but real-world document heterogeneity and unstructuredness disrupt the consistency of cross-modal embeddings. Recent late-interaction methods enhance image-text alignment through…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Weiqing Li , Jinyue Guo , Yaqi Wang , Haiyang Xiao , Yuewei Zhang , Guohua Liu , Hao Henry Wang

Contrastive learning has become pivotal in unsupervised representation learning, with frameworks like Momentum Contrast (MoCo) effectively utilizing large negative sample sets to extract discriminative features. However, traditional…

Machine Learning · Computer Science 2025-01-29 Duy Hoang , Huy Ngo , Khoi Pham , Tri Nguyen , Gia Bao , Huy Phan

We present ReMatch, a framework that leverages the generative strength of MLLMs for multimodal retrieval. Previous approaches treated an MLLM as a simple encoder, ignoring its generative nature, and under-utilising its compositional…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Qianying Liu , Xiao Liang , Zhiqiang Zhang , Zhongfei Qing , Fengfan Zhou , Yibo Chen , Xu Tang , Yao Hu , Paul Henderson

In this paper, we introduce LInK, a novel framework that integrates contrastive learning of performance and design space with optimization techniques for solving complex inverse problems in engineering design with discrete and continuous…

Machine Learning · Computer Science 2025-02-11 Amin Heyrani Nobari , Akash Srivastava , Dan Gutfreund , Kai Xu , Faez Ahmed

Contrastive learning is a discriminative approach that aims at grouping similar samples closer and diverse samples far from each other. It it an efficient technique to train an encoder generating distinguishable and informative…

Computer Vision and Pattern Recognition · Computer Science 2021-07-19 Qing Chen , Jian Zhang

Accurate and efficient prediction of the molecular properties of drugs is one of the fundamental problems in drug research and development. Recent advancements in representation learning have been shown to greatly improve the performance of…

Biomolecules · Quantitative Biology 2022-06-17 Hui Liu , Yibiao Huang , Xuejun Liu , Lei Deng

Sensory input from multiple sources is crucial for robust and coherent human perception. Different sources contribute complementary explanatory factors. Similarly, research studies often collect multimodal imaging data, each of which can…

Dense retrieval has achieved impressive advances in first-stage retrieval from a large-scale document collection, which is built on bi-encoder architecture to produce single vector representation of query and document. However, a document…

Computation and Language · Computer Science 2022-03-17 Shunyu Zhang , Yaobo Liang , Ming Gong , Daxin Jiang , Nan Duan

Retrosynthesis, of which the goal is to find a set of reactants for synthesizing a target product, is an emerging research area of deep learning. While the existing approaches have shown promising results, they currently lack the ability to…

Machine Learning · Computer Science 2021-06-04 Hankook Lee , Sungsoo Ahn , Seung-Woo Seo , You Young Song , Eunho Yang , Sung-Ju Hwang , Jinwoo Shin

Modeling the relationship between chemical structure and molecular activity is a key goal in drug development. Many benchmark tasks have been proposed for molecular property prediction, but these tasks are generally aimed at specific,…

Quantitative Methods · Quantitative Biology 2020-10-05 Samuel G. Finlayson , Matthew B. A. McDermott , Alex V. Pickering , Scott L. Lipnick , Isaac S. Kohane

Contrastive self-supervised learning has attracted significant research attention recently. It learns effective visual representations from unlabeled data by embedding augmented views of the same image close to each other while pushing away…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Yichen Zhang , Yifang Yin , Ying Zhang , Roger Zimmermann

Making decent multi-lingual sentence representations is critical to achieve high performances in cross-lingual downstream tasks. In this work, we propose a novel method to align multi-lingual embeddings based on the similarity of sentences…

Computation and Language · Computer Science 2024-05-29 Minsu Park , Seyeon Choi , Chanyeol Choi , Jun-Seong Kim , Jy-yong Sohn

Estimating correspondences between pairs of non-rigid deformable 3D shapes remains a significant challenge in computer vision and graphics. While deep functional map methods have become the go-to solution for addressing this problem, they…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Feifan Luo , Hongyang Chen

Contrastive learning has moved the state of the art for many tasks in computer vision and information retrieval in recent years. This poster is the first work that applies supervised contrastive learning to the task of product matching in…

Machine Learning · Computer Science 2022-05-03 Ralph Peeters , Christian Bizer