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Artificial intelligence (AI) is increasingly being used to augment and automate cyber operations, altering the scale, speed, and accessibility of malicious activity. These shifts raise urgent questions about when AI systems introduce…

Cryptography and Security · Computer Science 2026-01-27 Krystal Jackson , Deepika Raman , Jessica Newman , Nada Madkour , Charlotte Yuan , Evan R. Murphy

The rapid advancement of Large Language Models (LLMs) in biological research has significantly lowered the barrier to accessing complex bioinformatics knowledge, ex perimental design strategies, and analytical workflows. While these…

Cryptography and Security · Computer Science 2026-03-25 Protiva Das , Sovon Chakraborty , Sidhant Narula , Lucas Potter , Xavier-Lewis Palmer , Pratip Rana , Daniel Takabi , Mohammad Ghasemigol

We introduce Meta MLGym and MLGym-Bench, a new framework and benchmark for evaluating and developing LLM agents on AI research tasks. This is the first Gym environment for machine learning (ML) tasks, enabling research on reinforcement…

Hypothesis generation in biomedical research has traditionally centered on uncovering hidden relationships within vast scientific literature, often using methods like Literature-Based Discovery (LBD). Despite progress, current approaches…

Computation and Language · Computer Science 2025-11-13 Fuyi Yang , Chenchen Ye , Mingyu Derek Ma , Yijia Xiao , Matthew Yang , Wei Wang

Large Language Models (LLMs) and LLM-based agents show great promise in accelerating scientific research. Existing benchmarks for measuring this potential and guiding future development continue to evolve from pure recall and rote knowledge…

Rapidly evolving AI exhibits increasingly strong autonomy and goal-directed capabilities, accompanied by derivative systemic risks that are more unpredictable, difficult to control, and potentially irreversible. However, current AI safety…

Large language models (LLMs) have strong capabilities in solving diverse natural language processing tasks. However, the safety and security issues of LLM systems have become the major obstacle to their widespread application. Many studies…

Computation and Language · Computer Science 2024-01-12 Tianyu Cui , Yanling Wang , Chuanpu Fu , Yong Xiao , Sijia Li , Xinhao Deng , Yunpeng Liu , Qinglin Zhang , Ziyi Qiu , Peiyang Li , Zhixing Tan , Junwu Xiong , Xinyu Kong , Zujie Wen , Ke Xu , Qi Li

Large language models (LLMs) can enhance factuality via retrieval-augmented generation (RAG), but applying RAG to every query is unnecessary when the model-only answer is reliable. This motivates cascaded RAG: each query is first handled by…

Computation and Language · Computer Science 2026-05-20 Zijun Jia , Yuanchang Ye , Sen Jia , Yiyao Qian , Haoning Wang , Baojie Chen , Diyin Tang , Jinsong Yu , Zhiyuan Wang

With the widespread application of Large Language Models (LLMs), their associated security issues have become increasingly prominent, severely constraining their trustworthy deployment in critical domains. This paper proposes a novel safety…

Artificial Intelligence · Computer Science 2025-11-18 Qi Li , Jianjun Xu , Pingtao Wei , Jiu Li , Peiqiang Zhao , Jiwei Shi , Xuan Zhang , Yanhui Yang , Xiaodong Hui , Peng Xu , Wenqin Shao

As frontier Large Language Models (LLMs) increasingly saturate new benchmarks shortly after they are published, benchmarking itself is at a juncture: if frontier models keep improving, it will become increasingly hard for humans to generate…

Threat modeling is a crucial component of cybersecurity, particularly for industries such as banking, where the security of financial data is paramount. Traditional threat modeling approaches require expert intervention and manual effort,…

Cryptography and Security · Computer Science 2025-05-15 Tingmin Wu , Shuiqiao Yang , Shigang Liu , David Nguyen , Seung Jang , Alsharif Abuadbba

To understand and identify the unprecedented risks posed by rapidly advancing artificial intelligence (AI) models, Frontier AI Risk Management Framework in Practice presents a comprehensive assessment of their frontier risks. As Large…

Large Language Models (LLMs) are being deployed across various domains today. However, their capacity to solve Capture the Flag (CTF) challenges in cybersecurity has not been thoroughly evaluated. To address this, we develop a novel method…

The advent of Large Language Models (LLMs) has revolutionized various applications by providing advanced natural language processing capabilities. However, this innovation introduces new cybersecurity challenges. This paper explores the…

Cryptography and Security · Computer Science 2024-06-18 Stephen Burabari Tete

We introduce BikeBench, an engineering design benchmark for evaluating generative models on problems with multiple real-world objectives and constraints. As generative AI's reach continues to grow, evaluating its capability to understand…

Computational Engineering, Finance, and Science · Computer Science 2025-10-28 Lyle Regenwetter , Yazan Abu Obaideh , Fabien Chiotti , Ioanna Lykourentzou , Faez Ahmed

Pursuing artificial intelligence for biomedical science, a.k.a. AI Scientist, draws increasing attention, where one common approach is to build a copilot agent driven by Large Language Models (LLMs). However, to evaluate such systems,…

Computation and Language · Computer Science 2024-07-02 Xinna Lin , Siqi Ma , Junjie Shan , Xiaojing Zhang , Shell Xu Hu , Tiannan Guo , Stan Z. Li , Kaicheng Yu

As foundation models grow in both popularity and capability, researchers have uncovered a variety of ways that the models can pose a risk to the model's owner, user, or others. Despite the efforts of measuring these risks via benchmarks and…

Cryptography and Security · Computer Science 2025-06-04 David Piorkowski , Michael Hind , John Richards , Jacquelyn Martino

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

Agentic AI scientists equipped with domain-specific tools are rapidly entering scientific workflows across disciplines, with especially strong uptake in the life sciences where they can be used for literature synthesis, sequence analysis,…

Other Quantitative Biology · Quantitative Biology 2026-05-05 Kimon Antonios Provatas , Avery Self , Ioannis Mouratidis , Ilias Georgakopoulos-Soares

This paper introduces v0.5 of the AI Safety Benchmark, which has been created by the MLCommons AI Safety Working Group. The AI Safety Benchmark has been designed to assess the safety risks of AI systems that use chat-tuned language models.…

Computation and Language · Computer Science 2024-05-15 Bertie Vidgen , Adarsh Agrawal , Ahmed M. Ahmed , Victor Akinwande , Namir Al-Nuaimi , Najla Alfaraj , Elie Alhajjar , Lora Aroyo , Trupti Bavalatti , Max Bartolo , Borhane Blili-Hamelin , Kurt Bollacker , Rishi Bomassani , Marisa Ferrara Boston , Siméon Campos , Kal Chakra , Canyu Chen , Cody Coleman , Zacharie Delpierre Coudert , Leon Derczynski , Debojyoti Dutta , Ian Eisenberg , James Ezick , Heather Frase , Brian Fuller , Ram Gandikota , Agasthya Gangavarapu , Ananya Gangavarapu , James Gealy , Rajat Ghosh , James Goel , Usman Gohar , Sujata Goswami , Scott A. Hale , Wiebke Hutiri , Joseph Marvin Imperial , Surgan Jandial , Nick Judd , Felix Juefei-Xu , Foutse Khomh , Bhavya Kailkhura , Hannah Rose Kirk , Kevin Klyman , Chris Knotz , Michael Kuchnik , Shachi H. Kumar , Srijan Kumar , Chris Lengerich , Bo Li , Zeyi Liao , Eileen Peters Long , Victor Lu , Sarah Luger , Yifan Mai , Priyanka Mary Mammen , Kelvin Manyeki , Sean McGregor , Virendra Mehta , Shafee Mohammed , Emanuel Moss , Lama Nachman , Dinesh Jinenhally Naganna , Amin Nikanjam , Besmira Nushi , Luis Oala , Iftach Orr , Alicia Parrish , Cigdem Patlak , William Pietri , Forough Poursabzi-Sangdeh , Eleonora Presani , Fabrizio Puletti , Paul Röttger , Saurav Sahay , Tim Santos , Nino Scherrer , Alice Schoenauer Sebag , Patrick Schramowski , Abolfazl Shahbazi , Vin Sharma , Xudong Shen , Vamsi Sistla , Leonard Tang , Davide Testuggine , Vithursan Thangarasa , Elizabeth Anne Watkins , Rebecca Weiss , Chris Welty , Tyler Wilbers , Adina Williams , Carole-Jean Wu , Poonam Yadav , Xianjun Yang , Yi Zeng , Wenhui Zhang , Fedor Zhdanov , Jiacheng Zhu , Percy Liang , Peter Mattson , Joaquin Vanschoren