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The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural proxies for some of these states. Experimental results further…

Neurons and Cognition · Quantitative Biology 2015-09-04 James Kunert , Eli Shlizerman , Andrew Walker , J. Nathan Kutz

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set-point. This phenomenon is often referred to as mechanical homeostasis. In contradiction…

Computational Engineering, Finance, and Science · Computer Science 2021-09-23 Jonas F. Eichinger , Maximilian J. Grill , Iman Davoodi Kermani , Roland C. Aydin , Wolfgang A. Wall , Jay D. Humphrey , Christian J. Cyron

Quasiperiodic models are important physical platforms to explore Anderson transitions in low dimensional systems, yet the exact mobility edges (MEs) are generally hard to be determined analytically. To date, the MEs in only a few models can…

Disordered Systems and Neural Networks · Physics 2025-12-29 Hai-Tao Hu , Yang Chen , Xiaoshui Lin , Ai-Min Guo , Zijing Lin , Ming Gong

Identifying transition states -- saddle points on the potential energy surface connecting reactant and product minima -- is central to predicting kinetic barriers and understanding chemical reaction mechanisms. In this work, we train an…

Soft biological tissues exhibit a tendency to maintain a preferred state of tensile stress, known as tensional homeostasis, which is restored even after external mechanical stimuli. This macroscopic behavior can be described using the…

Machine Learning · Computer Science 2025-01-23 Hagen Holthusen , Tim Brepols , Kevin Linka , Ellen Kuhl

A first-principles based methodology for efficiently and accurately finding thermodynamically stable and metastable atomic structures is introduced and benchmarked. The approach is demonstrated for gas-phase metal-oxide clusters in…

The possibility of topological phase transition with or without a magnetic flux trapped in the cells of a class of decorated lattices is explored in details.Using a tight binding Hamiltonian and a real space decimation scheme we…

Mesoscale and Nanoscale Physics · Physics 2025-01-29 Sougata Biswas

We develop an efficient numerical algorithm for the identification of a large number of saddle points of the potential energy function of Lennard- Jones clusters. Knowledge of the saddle points allows us to find many thousand adjacent…

Condensed Matter · Physics 2009-10-31 G. Daldoss , O. Pilla , G. Viliani , G. Ruocco

We present a new method that enables the identification and analysis of both transition and metastable conformational states from atomistic or coarse-grained molecular dynamics (MD) trajectories. Our algorithm is presented and studied by…

Chemical Physics · Physics 2017-10-04 Linda Martini , Adam Kells , Gerhard Hummer , Nicolae-Viorel Buchete , Edina Rosta

Saddle-point models arise throughout optimization, optimal transport, robust learning, and control. In many applications, the relevant function f(x,y) is convex in x and concave in y, and preserving this geometry is essential for obtaining…

Optimization and Control · Mathematics 2026-05-29 Xavier Warin

Mesoscopic quantum systems exhibit complex many-body quantum phenomena, where interactions between spins and charges give rise to collective modes and topological states. Even simple, non-interacting theories display a rich landscape of…

Mesoscale and Nanoscale Physics · Physics 2021-12-13 Abigail N. Poteshman , Evelyn Tang , Lia Papadopoulos , Danielle S. Bassett , Lee C. Bassett

Latent space models assume that network ties are more likely between nodes that are closer together in an underlying latent space. Euclidean space is a popular choice for the underlying geometry, but hyperbolic geometry can mimic more…

Methodology · Statistics 2026-02-05 Jieyun Wang , Anna L. Smith

By dividing potential energy landscapes into basins of attractions surrounding minima and linking those basins that are connected by transition state valleys, a network description of energy landscapes naturally arises. These networks are…

Statistical Mechanics · Physics 2007-05-23 Jonathan P. K. Doye , Claire P. Massen

We deal here with three metastable systems: 1{\textdegree}- the dowser texture, 2{\textdegree}- supertwistedcholesterics and 3{\textdegree}- hypotwisted cholesterics. We outline remarkable properties of tropisms of the dowser texture…

Soft Condensed Matter · Physics 2023-06-21 P. Pieranski , M. Godinho

A method is proposed to identify target states that optimize a metastability index amongst a set of trial states and use these target states as milestones (or core sets) to build Markov State Models (MSMs). If the optimized metastability…

Statistical Mechanics · Physics 2016-08-03 Enrico Guarnera , Eric Vanden-Eijnden

In this work, we present a transition-state optimization protocol based on the Mode-Tracking algorithm [J. Chem. Phys. 118 (2003) 1634]. By calculating only the eigenvector of interest instead of diagonalizing the full Hessian matrix and…

Computational Physics · Physics 2015-07-24 Maike Bergeler , Carmen Herrmann , Markus Reiher

We put forth a theoretical framework for engineering a two-dimensional (2D) second-order topological superconductor (SOTSC) by utilizing a heterostructure: incorporating noncollinear magnetic textures between an $s$-wave superconductor and…

Mesoscale and Nanoscale Physics · Physics 2024-01-30 Pritam Chatterjee , Arnob Kumar Ghosh , Ashis K. Nandy , Arijit Saha

Finding index-1 saddle points is crucial for understanding phase transitions. In this work, we propose a simple yet efficient approach, the spring pair method (SPM), to accurately locate saddle points. Without requiring Hessian information,…

Mathematical Physics · Physics 2024-07-08 Gang Cui , Kai Jiang

Motivated by explosive releases of energy in fusion, space and astrophysical plasmas, we consider the nonlinear stability of stratified magnetohydrodynamic (MHD) equilibria against two-dimensional interchanges of straight magnetic-flux…

High Energy Astrophysical Phenomena · Physics 2024-12-10 David N. Hosking , David Wasserman , Steven C. Cowley

We investigate the spectral and transport properties of a two-arm tight-binding ladder perturbed by an external magnetic field following an Aubry-Andr\'e-Harper profile. The varying magnetic flux trapped in consecutive ladder-cells…

Mesoscale and Nanoscale Physics · Physics 2020-10-05 Sk Sajid , Arunava Chakrabarti