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Acoustic traps use forces exerted by sound waves to confine and transport small objects. The dynamics of an object moving in the force landscape of an acoustic trap can be significantly influenced by the inertia of the surrounding fluid…

Soft Condensed Matter · Physics 2024-03-19 Mia C. Morrell , David G. Grier

Experimental observations suggest that there are differences between the behavior of particles optically trapped in air and trapped in a liquid phase. We present a modified version of Mie Debye Spherical Aberration theory to numerically…

Optics · Physics 2015-05-19 D. R. Burnham , D. McGloin

Advances in optical trapping design principles have led to tremendous progress in manipulating nanoparticles (NPs) with diverse functionalities in different environments using bulky systems. However, efficient control and manipulation of…

We demonstrate the measurement of mass of the absorbing micro-particle trapped in air by optical forced oscillation. When the trapping light intensity is modulated sinusoidally, the particle in the trap undergoes forced oscillation and the…

Optics · Physics 2017-06-28 Jinda Lin , Jianliao Deng , Rong Wei , Yong-qing Li , Yuzhu Wang

Optical tweezers enable non-contact trapping of micro-scale objects using light. Despite their widespread use, it is currently not known how tightly it is possible to three-dimensionally trap micro-particles with a given photon budget.…

We put forward an enantioselective method for chiral nanoparticles using optical tweezers. We demonstrate that the optical trapping force in a typical, realistic optical tweezing setup with circularly-polarized trapping beams is sensitive…

Optics · Physics 2019-11-07 R. Ali , F. A. Pinheiro , F. S. S. Rosa , R. S. Dutra , P. A. Maia Neto

Optical tweezers exploit light--matter interactions to trap particles ranging from single atoms to micrometer-sized eukaryotic cells. For this reason, optical tweezers are a ubiquitous tool in physics, biology, and nanotechnology. Recently,…

Optical tweezers have found widespread application in many fields, from physics to biology. Here, we explain in detail how optical forces and torques can be described within the geometrical optics approximation and we show that this…

Optics · Physics 2015-06-18 Agnese Callegari , Mite Mijalkov , A. Burak Gököz , Giovanni Volpe

Multi-step assembly of individual protein building blocks is key to the formation of essential higher-order structures inside and outside of cells. Optical tweezers is a technique well suited to investigate the mechanics and dynamics of…

Biological Physics · Physics 2020-08-18 Kathrin Lehmann , Marjan Shayegan , Gerhard A. Blab , Nancy R. Forde

Entangled networks of stiff biopolymers exhibit complex dynamic response, emerging from the topological constraints that neighboring filaments impose upon each other. We propose a class of reference models for entanglement dynamics of stiff…

Soft Condensed Matter · Physics 2008-06-23 Felix Höfling , Tobias Munk , Erwin Frey , Thomas Franosch

Standard optical tweezers rely on optical forces that arise when a focused laser beam interacts with a microscopic particle: scattering forces, which push the particle along the beam direction, and gradient forces, which attract it towards…

When studying the motion of optically trapped particles on the $\mu s$ time scale, in low viscous media such as air, inertia cannot be neglected. Resolution of unusual and interesting behaviour not seen in colloidal trapping experiments is…

Soft Condensed Matter · Physics 2015-03-13 D. R. Burnham , P. J. Reece , D. McGloin

Selective single beam tweezers open tremendous perspectives in microfluidics and microbiology for the micromanipulation, assembly and mechanical properties testing of microparticles, cells and microorganisms. In optics, single beam optical…

Applied Physics · Physics 2022-05-23 Zhixiong Gong , Michael Baudoin

In spite of the widespread use of optical tweezers as a quantitative tool to measure small forces, there exists no unambiguous and simple experimental method for either validating its theoretically predicted form or empirically…

Soft Condensed Matter · Physics 2013-01-25 Deepak Kumar , Shankar Ghosh , S. Bhattacharya

Recently, acoustic tweezers based on an array of ultrasonic transducers have been reported taking inspiration from holographic optical tweezers. In the latter technique, the calibration of the optical trap is an essential procedure to…

Optical tweezers are a versatile tool that can be used to manipulate small particles including both motile and non-motile bacteria and cells. The orientation of a non-spherical particle within a beam depends on the shape of the particle and…

Fast and accurate 3D position detection in optical tweezers (OT) is essential for quantitatively monitoring subtle variations in the mechanical properties of microscopic systems ranging from biomolecules to cells and colloids. Because…

Optical tweezers have revolutionized particle manipulation at the micro- and nanoscale, playing a critical role in fields such as plasmonics, biophysics, and nanotechnology. While traditional optical trapping methods primarily rely on…

Optics · Physics 2025-03-31 Ashutosh Shukla , Rahul Chand , Sneha Boby , G. V. Pavan Kumar

Calibration of optically trapped particles in-vivo has been complicated given the frequency dependence and spatial inhomogeneity of the cytoplasmic viscosity, and the requirement of accurate knowledge of the medium refractive index.…

Biological Physics · Physics 2019-09-25 Rahul Vaippully , Vaibavi Ramanujan , Saumendra Bajpai , Basudev Roy

This work addresses the problem of uniquely determining a rotational motion from continuous time-dependent measurements within the frameworks of parallel-beam and diffraction tomography. The motivation stems from the challenge of imaging…

Functional Analysis · Mathematics 2025-10-22 Peter Elbau , Denise Schmutz