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A major impediment to a more complete understanding of barrier crossing and other single-molecule processes is the inability to directly visualize the trajectories and dynamics of atoms and molecules in reactions. Rather, the kinetics are…

Chemical Physics · Physics 2018-03-29 Patrick Figliozzi , Curtis W. Peterson , Stuart A. Rice , Norbert F. Scherer

We study the trajectories of a single colloidal particle as it hops between two energy wells A and B, which are sculpted using adjacent optical traps by controlling their respective power levels and separation. Whereas the dynamical…

Data Analysis, Statistics and Probability · Physics 2008-03-05 David Wu , Kingshuk Ghosh , Mandar Inamdar , Heun Jin Lee , Scott Fraser , Ken Dill , Rob Phillips

Driving energy consumption plays a major role in the navigation of mobile robots in challenging environments, especially if they are left to operate unattended under limited on-board power. This paper reports on first results of an…

Robotics · Computer Science 2021-04-06 Marco Visca , Arthur Bouton , Roger Powell , Yang Gao , Saber Fallah

We propose a new, nonparametric approach to learning and representing transition dynamics in Markov decision processes (MDPs), which can be combined easily with dynamic programming methods for policy optimisation and value estimation. This…

Machine Learning · Computer Science 2012-06-22 Steffen Grunewalder , Guy Lever , Luca Baldassarre , Massi Pontil , Arthur Gretton

Efficient computational methods that are capable of supporting experimental measures obtained at constant values of pH and redox potential are important tools as they serve to, among other things, provide additional atomic level information…

Chemical Physics · Physics 2018-09-21 Vinícius Wilian D. Cruzeiro , Adrian E. Roitberg

Iterative phase retrieval algorithms typically employ projections onto constraint subspaces to recover the unknown phases in the Fourier transform of an image, or, in the case of x-ray crystallography, the electron density of a molecule.…

Numerical Analysis · Mathematics 2025-10-20 Veit Elser

We describe a reverse integration approach for the exploration of low-dimensional effective potential landscapes. Coarse reverse integration initialized on a ring of coarse states enables efficient "navigation" on the landscape terrain:…

Chemical Physics · Physics 2015-05-13 Thomas A. Frewen , Gerhard Hummer , Ioannis G. Kevrekidis

Characterization of the primary events involved in the $cis-trans$ photoisomerization of the rhodopsin retinal chromophore was approximated by a minimum one-dimensional quantum-classical model. The developed mathematical model is identical…

As robotic systems continue to address emerging issues in areas such as logistics, mobility, manufacturing, and disaster response, it is increasingly important to rapidly generate safe and energy-efficient trajectories. In this article, we…

Robotics · Computer Science 2022-11-14 Logan E. Beaver , Roberto Tron , Christos G. Cassandras

While it is very common to model diffusion as a random walk by assuming memorylessness of the trajectory and diffusive step lengths, these assumptions can lead to significant errors. This paper describes the extent to which a physical…

Statistical Mechanics · Physics 2025-08-07 Ludovico Cademartiri

Accurate, yet computationally efficient energy functions are essential for state-of-the art molecular dynamics (MD) studies of condensed phase systems. Here, a generic workflow based on a combination of machine learning-based and empirical…

Chemical Physics · Physics 2025-07-01 Eric D. Boittier , Silvan Käser , Markus Meuwly

Constructing reduced representations of high-dimensional systems is a fundamental problem in physical chemistry. Many unsupervised machine learning methods can automatically find such low-dimensional representations. However, an often…

Chemical Physics · Physics 2024-04-04 Jakub Rydzewski

Response Surface Methodology (RSM) introduced in the paper (Box & Wilson, 1951) explores the relationships between explanatory and response variables in complex settings and provides a framework to identify correct settings for the…

Methodology · Statistics 2020-11-02 Karthik Srinivasan , Amit Kumar , Parameshwaran Iyer , Abhinav Joshi

We present a novel method for finding low dimensional views of high dimensional data: Targeted Projection Pursuit. The method proceeds by finding projections of the data that best approximate a target view. Two versions of the method are…

Quantitative Methods · Quantitative Biology 2007-05-23 J. Faith , R. Mintram , M. Angelova

In many experiments, the aim is to deduce an underlying multi-substate on-off kinetic scheme (KS) from the statistical properties of a two-state trajectory. However, the mapping of a KS into a two-state trajectory leads to the loss of…

Quantitative Methods · Quantitative Biology 2010-08-16 O. Flomenbom , R. J. Silbey

As modern power systems continue to evolve, accurate power load forecasting remains a critical issue in energy management. The phase space reconstruction method can effectively retain the inner chaotic property of power load from a system…

Signal Processing · Electrical Eng. & Systems 2024-07-30 Zihan Tang , Tianyao Ji , Wenhu Tang

Cross-modal embeddings form the foundation for multi-modal models. However, visualization methods for interpreting cross-modal embeddings have been primarily confined to traditional dimensionality reduction (DR) techniques like PCA and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yilin Ye , Junchao Huang , Xingchen Zeng , Jiazhi Xia , Wei Zeng

This paper presents a model for quasi two-dimensional MHD flows between two planes with small magnetic Reynolds number and constant transverse magnetic field orthogonal to the planes. A method is presented that allows to take 3D effects…

Fluid Dynamics · Physics 2020-06-30 Alban Pothérat , Joël Sommeria , René Moreau

Triply Periodic Minimal Surface (TPMS) structures have emerged as a new class of porous materials with variable geometries and favourable transport properties, making them promising for reactor internals in chemical engineering. However,…

We present a new efficient transition pathway search method based on the least action principle and the Gaussian process regression method. Most pathway search methods developed so far rely on string representations, which approximate a…

Computational Physics · Physics 2022-09-13 JaeHwan Shim , Juyong Lee , Jaejun Yu