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We propose a learning-based method for light-path construction in path tracing algorithms, which iteratively optimizes and samples from what we refer to as spatio-directional Gaussian mixture models (SDMMs). In particular, we approximate…

Graphics · Computer Science 2021-12-30 Ana Dodik , Marios Papas , Cengiz Öztireli , Thomas Müller

A data-driven framework is presented, that enables the prediction of quantities, either observations or parameters, given sufficient partial data. The framework is illustrated via a computational model of the deposition of Cu in a Chemical…

Coarse-grained modeling in molecular simulations serves not only to extend accessible time and length scales beyond atomistic limits, but also to reduce high-dimensional chemical data to low-dimensional representations that expose the…

Chemical Physics · Physics 2026-05-19 Michael N. Sakano , Alejandro Strachan

We apply Thermostatted Ring Polymer Molecular Dynamics (TRPMD), a recently-proposed approximate quantum dynamics method, to the computation of thermal reaction rates. Its short-time Transition-State Theory (TST) limit is identical to…

Chemical Physics · Physics 2015-08-20 Timothy J. H. Hele , Yury V. Suleimanov

Molecular dynamics simulations are a cornerstone in science, allowing to investigate from the system's thermodynamics to analyse intricate molecular interactions. In general, to create extended molecular trajectories can be a…

Computational Physics · Physics 2022-06-22 Ludwig Winkler , Klaus-Robert Müller , Huziel E. Sauceda

We develop a broadly-applicable computational method for the automatic exploration of the bimolecular multi-reaction mechanism. The current methodology mainly involves the high-energy Born-Oppenheimer molecular dynamics (BOMD) simulation…

Chemical Physics · Physics 2021-12-24 Qinghai Cui , Jiawei Peng , Chao Xu , Zhenggang Lan

This work introduces a hierarchical strategy for terrain-aware bipedal locomotion that integrates reduced-dimensional perceptual representations to enhance reinforcement learning (RL)-based high-level (HL) policies for real-time gait…

Robotics · Computer Science 2025-12-16 Guillermo A. Castillo , Himanshu Lodha , Ayonga Hereid

Mapping reaction pathways and transition states (TS) is fundamental to chemistry but computationally expensive at scale. The minimum energy pathway (MEP) dictates reaction rates and mechanisms, yet recovering it via electronic-structure…

Chemical Physics · Physics 2026-05-25 Rémi Schlama , Philippe Schwaller

We develop a novel method of replica-exchange molecular dynamics (REMD) simulation, mass-scaling REMD (MSREMD) method, which improves trajectory accuracy at high temperatures, and thereby contributes to numerical stability. In addition, the…

Statistical Mechanics · Physics 2015-06-19 Tetsuro Nagai , Takuya Takahashi

To interpret molecular dynamics (MD) simulations, it is common practice to reduce the dimensionality of the molecular coordinates to a low-dimensional collective variable $x$. Projecting the high-dimensional MD data onto $x$ yields a free…

Soft Condensed Matter · Physics 2026-02-25 Sofia Sartore , Daniel Nagel , Georg Diez , Gerhard Stock

Trajectory representation learning (TRL) maps trajectories to vectors that can then be used for various downstream tasks, including trajectory similarity computation, trajectory classification, and travel-time estimation. However, existing…

Machine Learning · Computer Science 2024-12-02 Silin Zhou , Shuo Shang , Lisi Chen , Christian S. Jensen , Panos Kalnis

In this paper we study the reconstruction of moving object densities from undersampled dynamic X-ray tomography in two dimensions. A particular motivation of this study is to use realistic measurement protocols for practical applications,…

Numerical Analysis · Mathematics 2018-03-28 Martin Burger , Hendrik Dirks , Lena Frerking , Andreas Hauptmann , Tapio Helin , Samuli Siltanen

Transition path theory provides a statistical description of the dynamics of a reaction in terms of local spatial quantities. In its original formulation, it is limited to reactions that consist of trajectories flowing from a reactant set A…

Data Analysis, Statistics and Probability · Physics 2022-09-21 Chatipat Lorpaiboon , Jonathan Weare , Aaron R. Dinner

Finding complex reaction and transformation pathways, involving many intermediate states, is in general not possible on the DFT level with existing simulation methods due to the very large number of required energy and force evaluations.…

Computational Physics · Physics 2019-11-20 Deb Sankar De , Marco Krummenacher , Bastian Schaefer , Stefan Goedecker

We extend ring-polymer molecular dynamics (RPMD) to allow for the direct simulation of general, electronically non-adiabatic chemical processes. The kinetically constrained (KC) RPMD method uses the imaginary-time path-integral…

Statistical Mechanics · Physics 2014-03-05 Artur R. Menzeleev , Franziska Bell , Thomas F. Miller

Popular methods for identifying transition paths between energy minima, such as the nudged elastic band and string methods, typically do not incorporate potential energy curvature information, leading to slow relaxation to the minimum…

Computational Physics · Physics 2019-03-11 Stela Makri , Christoph Ortner , James R. Kermode

The exponential computational cost of describing strongly correlated electrons can be mitigated by adopting a reduced density-matrix (RDM)-based description of the electronic structure. While variational two-electron RDM (v2RDM) methods can…

Chemical Physics · Physics 2026-01-06 Grier M. Jones , Run. R. Li , A. Eugene DePrince , Konstantinos D. Vogiatzis

Mass-conserving reaction-diffusion (MCRD) systems are widely used to model phase separation and pattern formation in cell polarity, biomolecular condensates, and ecological systems. Numerical simulations and formal asymptotic analysis…

Analysis of PDEs · Mathematics 2026-02-09 Xiaoqing He , Quan-Xing Liu , Dong Ye

Trajectory representation learning (TRL) maps trajectories to vectors that can be used for many downstream tasks. Existing TRL methods use either grid trajectories, capturing movement in free space, or road trajectories, capturing movement…

Machine Learning · Computer Science 2024-11-25 Silin Zhou , Shuo Shang , Lisi Chen , Peng Han , Christian S. Jensen

Transition State Theory is a central cornerstone in reaction dynamics. Its key step is the identification of a dividing surface that is crossed only once by all reactive trajectories. This assumption is often badly violated, especially when…

Chemical Physics · Physics 2015-05-07 F. Revuelta , Thomas Bartsch , R. M. Benito , F. Borondo