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Deep learning has been successfully applied to medical image segmentation, enabling accurate identification of regions of interest such as organs and lesions. This approach works effectively across diverse datasets, including those with…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Tianyi Ren , Juampablo Heras Rivera , Hitender Oswal , Yutong Pan , Agamdeep Chopra , Jacob Ruzevick , Mehmet Kurt

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor

Deep learning has shown superb performance in detecting objects and classifying images, ensuring a great promise for analyzing medical imaging. Translating the success of deep learning to medical imaging, in which doctors need to understand…

Computer Vision and Pattern Recognition · Computer Science 2022-10-03 Lennart Brocki , Wistan Marchadour , Jonas Maison , Bogdan Badic , Panagiotis Papadimitroulas , Mathieu Hatt , Franck Vermet , Neo Christopher Chung

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

With the adoption of machine learning-based solutions in routine clinical practice, the need for reliable interpretability tools has become pressing. Shapley values provide local explanations. The method gained popularity in recent years.…

Methodology · Statistics 2023-06-27 Lucile Ter-Minassian , Sahra Ghalebikesabi , Karla Diaz-Ordaz , Chris Holmes

In this work, we examine the effectiveness of an uncertainty quantification framework known as Evidential Deep Learning applied in the context of biomedical image segmentation. This class of models involves assigning Dirichlet distributions…

Image and Video Processing · Electrical Eng. & Systems 2025-04-24 Hai Siong Tan , Kuancheng Wang , Rafe Mcbeth

Deep learning models (DLMs) can achieve state-of-the-art performance in histopathology image segmentation and classification, but have limited deployment potential in real-world clinical settings. Uncertainty estimates of DLMs can increase…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Audrey Xie , Elhoucine Elfatimi , Sambuddha Ghosal , Pratik Shah

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Despite the recent improvements in overall accuracy, deep learning systems still exhibit low levels of robustness. Detecting possible failures is critical for a successful clinical integration of these systems, where each data point…

Image and Video Processing · Electrical Eng. & Systems 2019-10-14 Alain Jungo , Mauricio Reyes

Deep learning-based medical image analysis faces a significant barrier due to the lack of interpretability. Conventional explainable AI (XAI) techniques, such as Grad-CAM and SHAP, often highlight regions outside clinical interests. To…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Yuhao Zhang , Mingcheng Zhu , Zhiyao Luo

Despite the recent success of deep learning methods at achieving new state-of-the-art accuracy for medical image segmentation, some major limitations are still restricting their deployment into clinics. One major limitation of deep…

Image and Video Processing · Electrical Eng. & Systems 2023-05-30 Lucas Fidon

Accurate segmentation of carotid artery structures in histopathological images is vital for cardiovascular disease research. This study systematically evaluates ten deep learning segmentation models including classical architectures, modern…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Phongsakon Mark Konrad , Andrei-Alexandru Popa , Yaser Sabzehmeidani , Liang Zhong , Madhulika Tripathy , Andrei Constantinescu , Elisa A. Liehn , Serkan Ayvaz

In clinical prediction settings the importance of a high-dimensional feature like genomics is often assessed by evaluating the change in predictive performance when adding it to a set of traditional clinical variables. This approach is…

Machine Learning · Statistics 2026-03-06 Mark A. van de Wiel , Jeroen Goedhart , Martin Jullum , Kjersti Aas

Deep learning (DL) networks have recently been shown to outperform other segmentation methods on various public, medical-image challenge datasets [3,11,16], especially for large pathologies. However, in the context of diseases such as…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Tanya Nair , Doina Precup , Douglas L. Arnold , Tal Arbel

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Xinkai Zhao , Chaowei Fang , De-Jun Fan , Xutao Lin , Feng Gao , Guanbin Li

Accurate medical image segmentation is crucial for diagnosis and analysis. However, the models without calibrated uncertainty estimates might lead to errors in downstream analysis and exhibit low levels of robustness. Estimating the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Yanwu Yang , Xutao Guo , Yiwei Pan , Pengcheng Shi , Haiyan Lv , Ting Ma

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

Uncertainty estimation has been widely studied in medical image segmentation as a tool to provide reliability, particularly in deep learning approaches. However, previous methods generally lack effective supervision in uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuzhu Li , An Sui , Fuping Wu , Xiahai Zhuang

Deep learning has led to state-of-the-art results for many medical imaging tasks, such as segmentation of different anatomical structures. With the increased numbers of deep learning publications and openly available code, the approach to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Tom van Sonsbeek , Veronika Cheplygina
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