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Heart failure hospitalization is a severe burden on healthcare. How to predict and therefore prevent readmission has been a significant challenge in outcomes research. To address this, we propose a deep learning approach to predict…

Computation and Language · Computer Science 2019-12-24 Xiong Liu , Yu Chen , Jay Bae , Hu Li , Joseph Johnston , Todd Sanger

Heart failure (HF) is one of the leading causes of hospital admissions in the US. Readmission within 30 days after a HF hospitalization is both a recognized indicator for disease progression and a source of considerable financial burden to…

Machine Learning · Computer Science 2018-12-27 Ahmed Allam , Mate Nagy , George Thoma , Michael Krauthammer

High hospital readmission rates are associated with significant costs and health risks for patients. Therefore, it is critical to develop predictive models that can support clinicians to determine whether or not a patient will return to the…

Machine Learning · Computer Science 2025-04-01 Tiago Almeida , Plinio Moreno , Catarina Barata

Social determinants of health (SDOH) $-$ the myriad of circumstances in which people live, grow, and age $-$ play an important role in health outcomes. However, existing outcome prediction models often only use proxies of SDOH as features.…

Computation and Language · Computer Science 2024-07-16 Chase Fensore , Rodrigo M. Carrillo-Larco , Shivani A. Patel , Alanna A. Morris , Joyce C. Ho

Heart Failure (HF) affects millions of Americans and leads to high readmission rates, posing significant healthcare challenges. While Social Determinants of Health (SDOH) such as socioeconomic status and housing stability play critical…

Machine Learning · Computer Science 2025-09-29 Mingchen Shao , Youjeong Kang , Xiao Hu , Hyunjung Gloria Kwak , Carl Yang , Jiaying Lu

Large language models (LLMs) are increasingly used to generate summaries from clinical notes. However, their ability to preserve essential diagnostic information remains underexplored, which could lead to serious risks for patient care.…

Computation and Language · Computer Science 2026-02-20 Heloisa Oss Boll , Antonio Oss Boll , Leticia Puttlitz Boll , Ameen Abu Hanna , Iacer Calixto

Mitigating risk-of-readmission of Congestive Heart Failure (CHF) patients within 30 days of discharge is important because such readmissions are not only expensive but also critical indicator of provider care and quality of treatment.…

Developing accurate clinical prediction models is often bottlenecked by the difficulty of deriving meaningful structured features from unstructured EHR notes, a process that traditionally requires manual, unscalable clinical abstraction. In…

Clinical notes contain information about patients that goes beyond structured data like lab values and medications. However, clinical notes have been underused relative to structured data, because notes are high-dimensional and sparse. This…

Computation and Language · Computer Science 2020-12-01 Kexin Huang , Jaan Altosaar , Rajesh Ranganath

30-day hospital readmission is a long standing medical problem that affects patients' morbidity and mortality and costs billions of dollars annually. Recently, machine learning models have been created to predict risk of inpatient…

A crucial step within secondary analysis of electronic health records (EHRs) is to identify the patient cohort under investigation. While EHRs contain medical billing codes that aim to represent the conditions and treatments patients may…

With the increasing availability of patient data, modern medicine is shifting towards prospective healthcare. Electronic health records offer a variety of information useful for clinical patient characterization and the development of…

Machine Learning · Computer Science 2025-05-27 Fabio Azzalini , Tommaso Dolci , Marco Vagaggini

Although rapid advancements in Large Language Models (LLMs) are facilitating the integration of artificial intelligence-based applications and services in healthcare, limited research has focused on the systematic evaluation of medical…

Artificial Intelligence · Computer Science 2024-11-12 MD Ragib Shahriyear

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep…

Machine Learning · Computer Science 2019-11-13 Justin R. Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Hospital readmission within 30 days of discharge is a leading driver of morbidity, mortality, and avoidable healthcare expenditure in congestive heart failure (CHF). Current clinical risk stratification tools rely primarily on non-imaging…

With the proliferation of Electronic Health Records (EHRs), a critical challenge in building predictive models is determining the optimal historical data time window to maximize accuracy. This study investigates the impact of various…

Machine Learning · Computer Science 2026-05-04 Ramin Mohammadi , Vahab vahdat , Sarthak Jain , Amir T. Namin , Ramya Palacholla , Sagar Kamarthi

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

Machine Learning · Computer Science 2025-08-29 Rituparna Datta , Jiaming Cui , Zihan Guan , Vishal G. Reddy , Joshua C. Eby , Gregory Madden , Rupesh Silwal , Anil Vullikanti

Readmissions among Medicare beneficiaries are a major problem for the US healthcare system from a perspective of both healthcare operations and patient caregiving outcomes. Our study analyzes Medicare hospital readmissions using LSTM…

Machine Learning · Computer Science 2024-10-24 Xintao Li , Sibei Liu , Dezhi Yu , Yang Zhang , Xiaoyu Liu

Large pre-trained language models (LMs) have been widely adopted in biomedical and clinical domains, introducing many powerful LMs such as bio-lm and BioELECTRA. However, the applicability of these methods to real clinical use cases is…

Computation and Language · Computer Science 2022-11-16 Samuel Cahyawijaya , Bryan Wilie , Holy Lovenia , Huan Zhong , MingQian Zhong , Yuk-Yu Nancy Ip , Pascale Fung

Addressing heart failure (HF) as a prevalent global health concern poses difficulties in implementing innovative approaches for enhanced patient care. Predicting mortality rates in HF patients, in particular, is difficult yet critical,…

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