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While Multimodal Large Language Models (MLLMs) show promising performance in automated electrocardiogram interpretation, it remains unclear whether they genuinely perform actual step-by-step reasoning or just rely on superficial visual…

Machine Learning · Computer Science 2026-03-17 Jungwoo Oh , Hyunseung Chung , Junhee Lee , Min-Gyu Kim , Hangyul Yoon , Ki Seong Lee , Youngchae Lee , Muhan Yeo , Edward Choi

The electrocardiogram (ECG) is the gold standard for non-invasive diagnosis of cardiac pathologies and is a fundamental pillar of cardiovascular medicine. Recent progress in deep learning has led to the development of robust automated…

Objective: A novel structure based on channel-wise attention mechanism is presented in this paper. Embedding with the proposed structure, an efficient classification model that accepts multi-lead electrocardiogram (ECG) as input is…

Signal Processing · Electrical Eng. & Systems 2020-03-27 Hao Tung , Chao Zheng , Xinsheng Mao , Dahong Qian

Electrocardiogram is a useful diagnostic signal that can detect cardiac abnormalities by measuring the electrical activity generated by the heart. Due to its rapid, non-invasive, and richly informative characteristics, ECG has many emerging…

Machine Learning · Computer Science 2025-12-09 Hanhui Deng , Xinglin Li , Jie Luo , Di Wu

Multimodal large language models (MLLMs) are increasingly being applied in the medical field, particularly in medical imaging. However, developing MLLMs for ECG signals, which are crucial in clinical settings, has been a significant…

Computation and Language · Computer Science 2024-11-25 Haitao Li , Ziyu Li , Yiheng Mao , Ziyi Liu , Zhoujian Sun , Zhengxing Huang

Deep learning models for 12-lead electrocardiogram (ECG) analysis achieve high diagnostic performance but lack the intuitive interpretability required for clinical integration. Standard feature attribution methods are limited by the…

Image and Video Processing · Electrical Eng. & Systems 2026-05-01 Karol Dobiczek , Maciej Mozolewski , Szymon Bobek , Michał Szafarczyk , Peter van Dam , Grzegorz J. Nalepa

During the diagnostic process, clinicians leverage multimodal information, such as chief complaints, medical images, and laboratory-test results. Deep-learning models for aiding diagnosis have yet to meet this requirement. Here we report a…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Hong-Yu Zhou , Yizhou Yu , Chengdi Wang , Shu Zhang , Yuanxu Gao , Jia Pan , Jun Shao , Guangming Lu , Kang Zhang , Weimin Li

The electrocardiogram (ECG) is a key diagnostic tool in cardiovascular health. Single-lead ECG recording is integrated into both clinical-grade and consumer wearables. While self-supervised pretraining of foundation models on unlabeled ECGs…

Machine Learning · Computer Science 2025-12-03 Yuxuan Shu , Peter H. Charlton , Fahim Kawsar , Jussi Hernesniemi , Mohammad Malekzadeh

Due to the high stakes in medical decision-making, there is a compelling demand for interpretable deep learning methods in medical image analysis. Concept Bottleneck Models (CBM) have emerged as an active interpretable framework…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yibo Gao , Zheyao Gao , Xin Gao , Yuanye Liu , Bomin Wang , Xiahai Zhuang

Pandemic outbreaks such as COVID-19 occur unexpectedly, and need immediate action due to their potential devastating consequences on global health. Point-of-care routine assessments such as electrocardiogram (ECG), can be used to develop…

Signal Processing · Electrical Eng. & Systems 2023-01-12 Weijie Sun , Sunil Vasu Kalmady , Nariman Sepehrvand , Luan Manh Chu , Zihan Wang , Amir Salimi , Abram Hindle , Russell Greiner , Padma Kaul

Heart disease is the number one killer, and ECGs can assist in the early diagnosis and prevention of deadly outcomes. Accurate ECG interpretation is critical in detecting heart diseases; however, they are often misinterpreted due to a lack…

Machine Learning · Computer Science 2021-10-29 Dharma KC , Chicheng Zhang , Chris Gniady , Parth Sandeep Agarwal , Sushil Sharma

This work discusses the use of contrastive learning and deep learning for diagnosing cardiovascular diseases from electrocardiography (ECG) signals. While the ECG signals usually contain 12 leads (channels), many healthcare facilities and…

Signal Processing · Electrical Eng. & Systems 2023-04-24 Tue M. Cao , Nhat H. Tran , Phi Le Nguyen , Hieu Pham

We propose a new representation learning solution for the classification of cognitive load based on Electroencephalogram (EEG). Our method integrates both time and frequency domains by first passing the raw EEG signals through the…

Human-Computer Interaction · Computer Science 2025-11-18 Prithila Angkan , Amin Jalali , Paul Hungler , Ali Etemad

Transfer learning makes use of data or knowledge in one problem to help solve a different, yet related, problem. It is particularly useful in brain-computer interfaces (BCIs), for coping with variations among different subjects and/or…

Human-Computer Interaction · Computer Science 2020-05-12 Wen Zhang , Dongrui Wu

Deep learning has enabled ECG diagnostic models with strong performance in tasks such as arrhythmia classification and abnormality detection. However, accuracy alone is insufficient for clinical deployment because it does not explain why a…

Machine Learning · Computer Science 2026-05-20 Jong-Hwan Jang , Yong-yeon Jo

Deep learning has emerged as the preferred modeling approach for automatic ECG analysis. In this study, we investigate three elements aimed at improving the quantitative accuracy of such systems. These components consistently enhance…

Signal Processing · Electrical Eng. & Systems 2023-08-30 Temesgen Mehari , Nils Strodthoff

Electrocardiogram (ECG) signal is one of the most effective sources of information mainly employed for the diagnosis and prediction of cardiovascular diseases (CVDs) connected with the abnormalities in heart rhythm. Clearly, single modality…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Thinh Phan , Duc Le , Patel Brijesh , Donald Adjeroh , Jingxian Wu , Morten Olgaard Jensen , Ngan Le

The widespread emergence of smart devices for ECG has sparked demand for intelligent single-lead ECG-based diagnostic systems. However, it is challenging to develop a single-lead-based ECG interpretation model for multiple diseases…

Artificial Intelligence · Computer Science 2023-01-31 Yuzhen Qin , Li Sun , Hui Chen , Wei-qiang Zhang , Wenming Yang , Jintao Fei , Guijin Wang

Emotion recognition based on Electroencephalography (EEG) has gained significant attention and diversified development in fields such as neural signal processing and affective computing. However, the unique brain anatomy of individuals…

Signal Processing · Electrical Eng. & Systems 2024-05-31 Yihang Dong , Xuhang Chen , Yanyan Shen , Michael Kwok-Po Ng , Tao Qian , Shuqiang Wang

Electrocardiogram (ECG) is a widely used tool for assessing cardiac function due to its low cost and accessibility. Emergent research shows that ECGs can help make predictions on key outcomes traditionally derived from more complex…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yuan Gao , Sangwook Kim , Chris McIntosh