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Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Differentiating true tumor progression (TP) from treatment-related pseudoprogression (PsP) in glioblastoma remains challenging, especially at early follow-up. We present the first stage-specific, cross-sectional benchmarking of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Wenhao Guo , Golrokh Mirzaei

Convolutional neural networks have achieved excellent results in automatic medical image segmentation. In this study, we proposed a novel 3D multi-path DenseNet for generating the accurate glioblastoma (GBM) tumor contour from four…

Medical Physics · Physics 2021-02-25 Jie Fu , Kamal Singhrao , X. Sharon Qi , Yingli Yang , Dan Ruan , John H. Lewis

Glioblastomas are the most aggressive fast-growing primary brain cancer which originate in the glial cells of the brain. Accurate identification of the malignant brain tumor and its sub-regions is still one of the most challenging problems…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Ramy A. Zeineldin , Mohamed E. Karar , Franziska Mathis-Ullrich , Oliver Burgert

Purpose/Objective: Brain tumors result in 20 years of lost life on average. Standard therapies induce complex structural changes in the brain that are monitored through MRI. Recent developments in artificial intelligence (AI) enable…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Selena Huisman , Nordin Belkacemi , Vera Keil , Joost Verhoeff , Szabolcs David

Glioma is one of the most common and aggressive types of primary brain tumors. The accurate segmentation of subcortical brain structures is crucial to the study of gliomas in that it helps the monitoring of the progression of gliomas and…

Image and Video Processing · Electrical Eng. & Systems 2018-03-02 Lele Chen , Yue Wu , Adora M. DSouza , Anas Z. Abidin , Axel Wismuller , Chenliang Xu

DNA microarray technology enables the simultaneous measurement of expression levels of thousands of genes, thereby facilitating the understanding of the molecular mechanisms underlying complex diseases such as brain tumors and the…

Machine Learning · Computer Science 2025-08-29 Emine Akpinar , Batuhan Hangun , Murat Oduncuoglu , Oguz Altun , Onder Eyecioglu , Zeynel Yalcin

Brain tumor is a life-threatening problem and hampers the normal functioning of the human body. The average five-year relative survival rate for malignant brain tumors is 35.6 percent. For proper diagnosis and efficient treatment planning,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Vidhyapriya Ranganathan , Celshiya Udaiyar , Jaisree Jayanth , Meghaa P , Srija B , Uthra S

According to the 2021 World Health Organization (WHO) Classification scheme for gliomas, glioma segmentation is a very important basis for diagnosis and genotype prediction. In general, 3D multimodal brain MRI is an effective diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Xiaoyu Shi , Shurong Chai , Yinhao Li , Jingliang Cheng , Jie Bai , Guohua Zhao , Yen-Wei Chen

Gliomas are aggressive brain tumors that require accurate imaging-based diagnosis, with segmentation playing a critical role in evaluating morphology and treatment decisions. Manual delineation of gliomas is time-consuming and prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Cecilia Diana-Albelda , Roberto Alcover-Couso , Álvaro García-Martín , Jesus Bescos , Marcos Escudero-Viñolo

Brain tumor is the most common and deadliest disease that can be found in all age groups. Generally, MRI modality is adopted for identifying and diagnosing tumors by the radiologists. The correct identification of tumor regions and its type…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Sachin Gupta , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

This study presents a multi-faceted approach combining stereotactic biopsy with standard clinical open-craniotomy for sample collection, voxel-wise analysis of MR images, regression-based Generalized Additive Models (GAM), & whole-exome…

Brain tumor segmentation is a critical task for tumor volumetric analyses and AI algorithms. However, it is a time-consuming process and requires neuroradiology expertise. While there has been extensive research focused on optimizing brain…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Partoo Vafaeikia , Matthias W. Wagner , Uri Tabori , Birgit B. Ertl-Wagner , Farzad Khalvati

Brain Metastases (BM) are a large contributor to mortality of patients with cancer. They are treated with Stereotactic Radiosurgery (SRS) and monitored with Magnetic Resonance Imaging (MRI) at regular follow-up intervals according to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Lorenz Achim Kuhn , Daniel Abler , Jonas Richiardi , Andreas F. Hottinger , Luis Schiappacasse , Vincent Dunet , Adrien Depeursinge , Vincent Andrearczyk

Objective: To report imaging protocol and scheduling variance in routine care of glioblastoma patients in order to demonstrate challenges of integrating deep-learning models in glioblastoma care pathways. Additionally, to understand the…

Brain tumor segmentation is an active research area due to the difficulty in delineating highly complex shaped and textured tumors as well as the failure of the commonly used U-Net architectures. The combination of different neural…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lanhong Yao , Zheyuan Zhang , Ulas Bagci

Medical image analysis has significantly benefited from advancements in deep learning, particularly in the application of Generative Adversarial Networks (GANs) for generating realistic and diverse images that can augment training datasets.…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Meng Zhou , Matthias W Wagner , Uri Tabori , Cynthia Hawkins , Birgit B Ertl-Wagner , Farzad Khalvati

Gliomas are the most common primary brain tumors, evolving from the cerebral supportive cells. For clinical follow-up, the evaluation of the preoperative tumor volume is essential. Volumetric assessment of tumor volume with manual…

Computational Engineering, Finance, and Science · Computer Science 2011-03-10 Jan Egger , Miriam H. A. Bauer , Daniela Kuhnt , Christoph Kappus , Barbara Carl , Bernd Freisleben , Christopher Nimsky

Precise automated delineation of post-operative gross tumor volume in glioblastoma cases is challenging and time-consuming owing to the presence of edema and the deformed brain tissue resulting from the surgical tumor resection. To develop…