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Quantum Computing (QC) offers outstanding potential for molecular characterization and drug discovery, particularly in solving complex properties like the Ground State Energy (GSE) of biomolecules. However, QC faces challenges due to…

Chemical Physics · Physics 2024-12-17 Laia Coronas Sala , Parfait Atchade-Adelemou

Quantum machine learning (QML) is emerging as an application of quantum computing with the potential to deliver quantum advantage, but its realisation for practical applications remains impeded by challenges. Amongst those, a key barrier is…

Quantum Computing (QC) claims to improve the efficiency of solving complex problems, compared to classical computing. When QC is integrated with Machine Learning (ML), it creates a Quantum Machine Learning (QML) system. This paper aims to…

Quantum Physics · Physics 2025-06-11 Kamila Zaman , Alberto Marchisio , Muhammad Abdullah Hanif , Muhammad Shafique

Quantum-inspired machine learning (QiML) employs mathematical principles from quantum theory, such as Hilbert-space representations and quantum state discrimination, to enhance classical learning algorithms. In this work, we investigate the…

Machine Learning · Computer Science 2026-05-14 Bikash K. Behera , Giuseppe Sergioli , Roberto Giuntini

Quantum generative models offer a promising new direction in machine learning by leveraging quantum circuits to enhance data generation capabilities. In this study, we propose a hybrid quantum-classical image generation framework that…

Quantum Physics · Physics 2025-04-04 Chi-Sheng Chen , Wei An Hou , Hsiang-Wei Hu , Zhen-Sheng Cai

Self-Attention Mechanism (SAM) excels at distilling important information from the interior of data to improve the computational efficiency of models. Nevertheless, many Quantum Machine Learning (QML) models lack the ability to distinguish…

Quantum Physics · Physics 2023-10-13 Ren-Xin Zhao , Jinjing Shi , Xuelong Li

The field of Quantum Machine Learning (QML) has emerged recently in the hopes of finding new machine learning protocols or exponential speedups for classical ones. Apart from problems with vanishing gradients and efficient encoding methods,…

Machine Learning · Computer Science 2023-10-17 Hannah Helgesen , Michael Felsberg , Jan-Åke Larsson

Learning with large-scale datasets and information-critical applications, such as in High Energy Physics (HEP), demands highly complex, large-scale models that are both robust and accurate. To tackle this issue and cater to the learning…

Machine Learning · Computer Science 2026-04-20 Abhishek Sawaika , Durga Pritam Suggisetti , Udaya Parampalli , Rajkumar Buyya

The accurate prediction of chromosomal instability from the morphology of circulating tumor cells (CTCs) enables real-time detection of CTCs with high metastatic potential in the context of liquid biopsy diagnostics. However, it presents a…

Quantum Machine Learning (QML) is considered one of the most promising applications of Quantum Computing in the Noisy Intermediate Scale Quantum (NISQ) era for the impact it is thought to have in the near future. Although promising…

Quantum Physics · Physics 2025-08-22 Valeria Repetto , Elia Giuseppe Ceroni , Giuseppe Buonaiuto , Romina D'Aurizio

We propose an approach to generative quantum machine learning that overcomes the fundamental scaling issues of variational quantum circuits. The core idea is to use a class of generative models based on instantaneous quantum polynomial…

Quantum Physics · Physics 2026-02-09 Erik Recio-Armengol , Shahnawaz Ahmed , Joseph Bowles

We present a large-scale experimental study of quantum-computing-based molecular simulation carried out on IQM's Sirius 24-qubit superconducting processor, utilizing up to 16 operational qubits. The work employs Sample-based Quantum…

Quantum machine learning (QML) has emerged as a promising field that leans on the developments in quantum computing to explore large complex machine learning problems. Recently, some purely quantum machine learning models were proposed such…

Quantum Physics · Physics 2021-06-02 Mahdi Chehimi , Walid Saad

Quantum computers have the opportunity to be transformative for a variety of computational tasks. Recently, there have been proposals to use the unsimulatably of large quantum devices to perform regression, classification, and other machine…

This study explores the implementation of large Quantum Restricted Boltzmann Machines (QRBMs), a key advancement in Quantum Machine Learning (QML), as generative models on D-Wave's Pegasus quantum hardware to address dataset imbalance in…

Emerging Technologies · Computer Science 2025-07-30 Salvatore Sinno , Markus Bertl , Arati Sahoo , Bhavika Bhalgamiya , Thomas Groß , Nicholas Chancellor

We propose quantum-selected configuration interaction (QSCI), a class of hybrid quantum-classical algorithms for calculating the ground- and excited-state energies of many-electron Hamiltonians on noisy quantum devices. Suppose that an…

Quantum Physics · Physics 2023-02-23 Keita Kanno , Masaya Kohda , Ryosuke Imai , Sho Koh , Kosuke Mitarai , Wataru Mizukami , Yuya O. Nakagawa

In the NISQ (Noisy intermediate-scale quantum) area, Quantum computers can be utilized for deep learning by treating variational quantum circuits as neural network models. This can be achieved by first encoding the input data onto quantum…

High Energy Physics - Phenomenology · Physics 2023-11-29 A. Hammad , Kyoungchul Kong , Myeonghun Park , Soyoung Shim

Quantum machine learning is one of the most promising applications of quantum computing in the Noisy Intermediate-Scale Quantum(NISQ) era. Here we propose a quantum convolutional neural network(QCNN) inspired by convolutional neural…

Quantum Physics · Physics 2021-04-23 ShiJie Wei , YanHu Chen , ZengRong Zhou , GuiLu Long

Identification of cancer driver genes is fundamental for the development of targeted therapeutic interventions. The integration of mutational profiles with protein-protein interaction (PPI) networks offers a promising avenue for their…

Quantum Physics · Physics 2025-11-05 Patricia Marques , Andreas Wichert , Duarte Magano , Bruno Coutinho

Significant challenges remain with the development of macroscopic quantum computing, hardware problems of noise, decoherence, and scaling, software problems of error correction, and, most important, algorithm construction. Finding truly…

Quantum Physics · Physics 2022-12-05 James E. Steck , Nathan L. Thompson , Elizabeth C. Behrman
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