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Major depressive disorder (MDD) impacts more than 300 million people worldwide, highlighting a significant public health issue. However, the uneven distribution of medical resources and the complexity of diagnostic methods have resulted in…

Computation and Language · Computer Science 2025-05-02 Yuyang Sha , Hongxin Pan , Wei Xu , Weiyu Meng , Gang Luo , Xinyu Du , Xiaobing Zhai , Henry H. Y. Tong , Caijuan Shi , Kefeng Li

Preliminary detection of mild depression could immensely help in effective treatment of the common mental health disorder. Due to the lack of proper awareness and the ample mix of stigmas and misconceptions present within the society,…

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Depression is a leading cause of death worldwide, and the diagnosis of depression is nontrivial. Multimodal learning is a popular solution for automatic diagnosis of depression, and the existing works suffer two main drawbacks: 1) the…

Multimedia · Computer Science 2023-01-03 Chengbo Yuan , Qianhui Xu , Yong Luo

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Individual's general well-being is greatly impacted by mental health conditions including depression and Post-Traumatic Stress Disorder (PTSD), underscoring the importance of early detection and precise diagnosis in order to facilitate…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

Multimodal Large Models (MLLMs) have achieved remarkable progress in vision-language understanding and generation tasks. However, existing MLLMs typically rely on static modality fusion strategies, which treat all modalities equally…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Hiroshi Tanaka , Anika Rao , Hana Satou , Michael Johnson , Sofia García

Depression is a widespread mental health issue affecting diverse age groups, with notable prevalence among college students and the elderly. However, existing datasets and detection methods primarily focus on young adults, neglecting the…

Depression is a growing concern gaining attention in both public discourse and AI research. While deep neural networks (DNNs) have been used for recognition, they still lack real-world effectiveness. Large language models (LLMs) show strong…

Human-Computer Interaction · Computer Science 2025-08-27 Yupei Li , Shuaijie Shao , Manuel Milling , Björn W. Schuller

Depression has proven to be a significant public health issue, profoundly affecting the psychological well-being of individuals. If it remains undiagnosed, depression can lead to severe health issues, which can manifest physically and even…

Human-Computer Interaction · Computer Science 2024-12-03 Chayan Tank , Sarthak Pol , Vinayak Katoch , Shaina Mehta , Avinash Anand , Rajiv Ratn Shah

Clinical depression or Major Depressive Disorder (MDD) is a common and serious medical illness. In this paper, a deep recurrent neural network-based framework is presented to detect depression and to predict its severity level from speech.…

Human-Computer Interaction · Computer Science 2020-03-13 Emna Rejaibi , Ali Komaty , Fabrice Meriaudeau , Said Agrebi , Alice Othmani

Background Major depressive disorder (MDD) is a leading cause of global disability, yet current diagnostic approaches often rely on subjective assessments and lack the ability to integrate multimodal clinical information. Large language…

Machine Learning · Computer Science 2025-09-30 Yuyang Sha , Hongxin Pan , Gang Luo , Caijuan Shi , Jing Wang , Kefeng Li

The growing prevalence and complexity of mental health disorders present significant challenges for accurate diagnosis and treatment, particularly in understanding the interplay between co-occurring conditions. Mental health disorders, such…

Artificial Intelligence · Computer Science 2024-12-06 Abdelrahaman A. Hassan , Radwa J. Hanafy , Mohammed E. Fouda

While multimodal data integrating diverse imaging and clinical tabular records is crucial for accurate medical diagnosis, the arbitrary absence of specific modalities is prevalent in clinical practice, severely degrading the performance of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Tianling Liu , Lequan Yu , Tong Han , Liang Wan

Medical multi-modal pre-training has revealed promise in computer-aided diagnosis by leveraging large-scale unlabeled datasets. However, existing methods based on masked autoencoders mainly rely on data-level reconstruction tasks, but lack…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yupei Zhang , Li Pan , Qiushi Yang , Tan Li , Zhen Chen

Uncovering cause-and-effect mechanisms from data is fundamental to scientific progress. While large language models (LLMs) show promise for enhancing causal discovery (CD) from unstructured data, their application to the increasingly…

Machine Learning · Computer Science 2025-10-31 Jin Li , Shoujin Wang , Qi Zhang , Feng Liu , Tongliang Liu , Longbing Cao , Shui Yu , Fang Chen

Depression is one of the most prevalent mental disorders, which seriously affects one's life. Traditional depression diagnostics commonly depends on rating with scales, which can be labor-intensive and subjective. In this context, Automatic…

Machine Learning · Computer Science 2022-03-02 Yanrong Guo , Chenyang Zhu , Shijie Hao , Richang Hong

Major depressive disorder (MDD) is a common mental disorder that typically affects a person's mood, cognition, behavior, and physical health. Resting-state functional magnetic resonance imaging (rs-fMRI) data are widely used for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-10 Yunling Ma , Chaojun Zhang , Xiaochuan Wang , Qianqian Wang , Liang Cao , Limei Zhang , Mingxia Liu

Multimodal depression detection is an important research topic that aims to predict human mental states using multimodal data. Previous methods treat different modalities equally and fuse each modality by na\"ive mathematical operations…

Computation and Language · Computer Science 2024-01-09 Yuntao Wei , Yuzhe Zhang , Shuyang Zhang , Hong Zhang