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Alzheimer's disease (AD) is a progressive brain disorder that causes memory and functional impairments. The advances in machine learning and publicly available medical datasets initiated multiple studies in AD diagnosis. In this work, we…

Alongside neuroimaging such as MRI scans and PET, Alzheimer's disease (AD) datasets contain valuable tabular data including AD biomarkers and clinical assessments. Existing computer vision approaches struggle to utilize this additional…

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power…

Background:Cognitive assessments represent the most common clinical routine for the diagnosis of Alzheimer's Disease (AD). Given a large number of cognitive assessment tools and time-limited office visits, it is important to determine a…

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…

Alzheimer's disease (AD) affects 50 million people worldwide and is projected to overwhelm 152 million by 2050. AD is characterized by cognitive decline due partly to disruptions in metabolic brain connectivity. Thus, early and accurate…

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely impairs cognitive function and quality of life. Timely intervention in AD relies heavily on early and precise diagnosis, which remains challenging due to the…

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease. Early and precise diagnosis of AD is crucial for timely intervention and treatment planning to alleviate the progressive neurodegeneration. However, most…

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer\{'}s disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…

Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining…

Alzheimer's disease (AD) is an incurable neurodegenerative condition leading to cognitive and functional deterioration. Given the lack of a cure, prompt and precise AD diagnosis is vital, a complex process dependent on multiple factors and…

Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate detailed patient trajectories. We use data comprising…

Alzheimer's disease (AD) is the most common form of dementia, which causes problems with memory, thinking and behavior. Growing evidence has shown that the brain connectivity network experiences alterations for such a complex disease.…