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Weakly supervised semantic segmentation (WSSS) in histopathology seeks to reduce annotation cost by learning from image-level labels, yet it remains limited by inter-class homogeneity, intra-class heterogeneity, and the region-shrinkage…

Weakly supervised image segmentation with image-level labels has drawn attention due to the high cost of pixel-level annotations. Traditional methods using Class Activation Maps (CAMs) often highlight only the most discriminative regions,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Qingchen Tang , Lei Fan , Maurice Pagnucco , Yang Song

Recent attention has been devoted to the pursuit of learning semantic segmentation models exclusively from image tags, a paradigm known as image-level Weakly Supervised Semantic Segmentation (WSSS). Existing attempts adopt the Class…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Ye Du , Zehua Fu , Qingjie Liu

Weakly-Supervised Semantic Segmentation (WSSS) aims to train segmentation models using image data with only image-level supervision. Since precise pixel-level annotations are not accessible, existing methods typically focus on producing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Ci-Siang Lin , Chien-Yi Wang , Yu-Chiang Frank Wang , Min-Hung Chen

Weakly-Supervised Semantic Segmentation (WSSS) methods with image-level labels generally train a classification network to generate the Class Activation Maps (CAMs) as the initial coarse segmentation labels. However, current WSSS methods…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 Lixiang Ru , Bo Du , Yibing Zhan , Chen Wu

Improving the feature representation ability is the foundation of many whole slide pathological image (WSIs) tasks. Recent works have achieved great success in pathological-specific self-supervised learning (SSL). However, most of them only…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Zhimiao Yu , Tiancheng Lin , Yi Xu

Scarcity of pixel-level labels is a significant challenge in practical scenarios. In specific domains like industrial smoke, acquiring such detailed annotations is particularly difficult and often requires expert knowledge. To alleviate…

Computer Vision and Pattern Recognition · Computer Science 2025-07-30 Zheyuan Zhang , Yen-chia Hsu

Weakly-supervised learning (WSL) has recently triggered substantial interest as it mitigates the lack of pixel-wise annotations. Given global image labels, WSL methods yield pixel-level predictions (segmentations), which enable to interpret…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Chu Han , Jiatai Lin , Jinhai Mai , Yi Wang , Qingling Zhang , Bingchao Zhao , Xin Chen , Xipeng Pan , Zhenwei Shi , Xiaowei Xu , Su Yao , Lixu Yan , Huan Lin , Zeyan Xu , Xiaomei Huang , Guoqiang Han , Changhong Liang , Zaiyi Liu

The costly process of obtaining semantic segmentation labels has driven research towards weakly supervised semantic segmentation (WSSS) methods, using only image-level, point, or box labels. The lack of dense scene representation requires…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Peri Akiva , Kristin Dana

Semantic segmentation is a core computer vision problem, but the high costs of data annotation have hindered its wide application. Weakly-Supervised Semantic Segmentation (WSSS) offers a cost-efficient workaround to extensive labeling in…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Elham Ravanbakhsh , Cheng Niu , Yongqing Liang , J. Ramanujam , Xin Li

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

This work proposes a novel approach beyond supervised learning for effective pathological image analysis, addressing the challenge of limited robust labeled data. Pathological diagnosis of diseases like cancer has conventionally relied on…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Joonhyeon Song , Seohwan Yun , Seongho Yoon , Joohyeok Kim , Sangmin Lee

Weakly supervised semantic segmentation (WSSS) in histopathology relies heavily on classification backbones, yet these models often localize only the most discriminative regions and struggle to capture the full spatial extent of tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Khang Le , Ha Thach , Anh M. Vu , Trang T. K. Vo , Han H. Huynh , David Yang , Minh H. N. Le , Thanh-Huy Nguyen , Akash Awasthi , Chandra Mohan , Zhu Han , Hien Van Nguyen

With the rapid advancement of deep learning, computational pathology has made significant progress in cancer diagnosis and subtyping. Tissue segmentation is a core challenge, essential for prognosis and treatment decisions. Weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-01-08 Hongyi Wu , Hong Zhang

Weakly supervised semantic segmentation (WSSS) trains dense pixel-level segmentation models from partial or coarse annotations such as bounding boxes, scribbles, or image-level tags. While recent work leverages foundation models such as the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Stefano Colamonaco , Andrei-Bogdan Florea , Jaron Maene

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Weakly Supervised Semantic Segmentation (WSSS) with image-level labels has gained attention for its cost-effectiveness. Most existing methods emphasize inter-class separation, often neglecting the shared semantics among related categories…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Wangyu Wu , Zhenhong Chen , Xiaowen Ma , Wenqiao Zhang , Xianglin Qiu , Siqi Song , Xiaowei Huang , Fei Ma , Jimin Xiao

In pathology, the spatial distribution and proportions of tissue types are key indicators of disease progression, and are more readily available than fine-grained annotations. However, these assessments are rarely mapped to pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Yangping Li , Thomas Pinetz , Michael Hölzel , Marieta Toma , Alexander Effland

Acquiring annotations for whole slide images (WSIs)-based deep learning tasks, such as creating tissue segmentation masks or detecting mitotic figures, is a laborious process due to the extensive image size and the significant manual work…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Jingna Qiu , Marc Aubreville , Frauke Wilm , Mathias Öttl , Jonas Utz , Maja Schlereth , Katharina Breininger
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