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Estimating rate coefficients from complex chemical reactions is essential for advancing detailed chemistry. However, the stiffness inherent in real-world atmospheric chemistry systems poses severe challenges, leading to training instability…

Machine Learning · Computer Science 2025-09-01 Wenqing Peng , Zhi-Song Liu , Michael Boy

Language is an effective medium for bi-directional communication in human-robot teams. To infer the meaning of many instructions, robots need to construct a model of their surroundings that describe the spatial, semantic, and metric…

Robotics · Computer Science 2019-09-24 Ethan Fahnestock , Siddharth Patki , Thomas M. Howard

We report a flexible multi-modal mechanics language model, MeLM, applied to solve various nonlinear forward and inverse problems, that can deal with a set of instructions, numbers and microstructure data. The framework is applied to various…

Materials Science · Physics 2023-10-20 Markus J. Buehler

To effectively simulate the combustion of hydrocarbon-fueled supersonic engines, such as rocket-based combined cycle (RBCC) engines, a detailed mechanism for chemistry is usually required but computationally prohibitive. In order to…

Fluid Dynamics · Physics 2020-03-03 Jian An , Guo Qiang He , Kai Hong Luo , Fei Qin , Bing Liu

For the investigation of chemical reaction networks, the efficient and accurate determination of all relevant intermediates and elementary reactions is mandatory. The complexity of such a network may grow rapidly, in particular if reactive…

Chemical Physics · Physics 2016-01-08 Maike Bergeler , Gregor N. Simm , Jonny Proppe , Markus Reiher

Situationally-aware artificial agents operating with competence in natural environments face several challenges: spatial awareness, object affordance detection, dynamic changes and unpredictability. A critical challenge is the agent's…

Robotics · Computer Science 2025-07-29 Mihai Pomarlan , Stefano De Giorgis , Rachel Ringe , Maria M. Hedblom , Nikolaos Tsiogkas

Retrosynthesis, the process of breaking down a target molecule into simpler precursors through a series of valid reactions, stands at the core of organic chemistry and drug development. Although recent machine learning (ML) research has…

Artificial Intelligence · Computer Science 2026-05-12 Haorui Wang , Jeff Guo , Lingkai Kong , Rampi Ramprasad , Philippe Schwaller , Yuanqi Du , Chao Zhang

Automated commonsense reasoning is essential for building human-like AI systems featuring, for example, explainable AI. Event Calculus (EC) is a family of formalisms that model commonsense reasoning with a sound, logical basis. Previous…

Artificial Intelligence · Computer Science 2021-06-29 Joaquín Arias , Manuel Carro , Zhuo Chen , Gopal Gupta

A major bottleneck in developing sustainable processes and materials is a lack of property data. Recently, machine learning approaches have vastly improved previous methods for predicting molecular properties. However, these machine…

Chemical Physics · Physics 2023-09-25 Benedikt Winter , Philipp Rehner , Timm Esper , Johannes Schilling , André Bardow

Natural language processing models have emerged that can generate usable software and automate a number of programming tasks with high fidelity. These tools have yet to have an impact on the chemistry community. Yet, our initial testing…

Statistical Mechanics · Physics 2023-01-11 Glen M. Hocky , Andrew D. White

Procedure planning requires a model to predict a sequence of actions that transform a start visual observation into a goal in instructional videos. While most existing methods rely primarily on visual observations as input, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Lei Shi , Victor Aregbede , Andreas Persson , Martin Längkvist , Amy Loutfi , Stephanie Lowry

Language enables humans to share knowledge, reason about the world, and pass on strategies for survival and innovation across generations. At the heart of this process is not just the ability to communicate but also the remarkable…

Computation and Language · Computer Science 2026-02-25 Jan Philip Wahle

Descriptor generation methods using latent representations of encoder$-$decoder (ED) models with SMILES as input are useful because of the continuity of descriptor and restorability to the structure. However, it is not clear how the…

Chemical Physics · Physics 2023-04-14 Shumpei Nemoto , Tadahaya Mizuno , Hiroyuki Kusuhara

Molecular optimization is a central task in drug discovery that requires precise structural reasoning and domain knowledge. While large language models (LLMs) have shown promise in generating high-level editing intentions in natural…

Machine Learning · Computer Science 2025-10-17 Wenyu Zhu , Chengzhu Li , Xiaohe Tian , Yifan Wang , Yinjun Jia , Jianhui Wang , Bowen Gao , Ya-Qin Zhang , Wei-Ying Ma , Yanyan Lan

Complex Event Recognition and Forecasting (CER/F) techniques attempt to detect, or even forecast ahead of time, event occurrences in streaming input using predefined event patterns. Such patterns are not always known in advance, or they…

Artificial Intelligence · Computer Science 2022-09-01 Nikos Katzouris , Georgios Paliouras

Since the advent of machine learning, interpretability has remained a persistent challenge, becoming increasingly urgent as generative models support high-stakes applications in drug and material discovery. Recent advances in large language…

Machine Learning · Computer Science 2025-12-10 Jaron Cohen , Alexander G. Hasson , Sara Tanovic

Chemists in search of structure-property relationships face great challenges due to limited high quality, concordant datasets. Machine learning (ML) has significantly advanced predictive capabilities in chemical sciences, but these modern…

Machine Learning · Computer Science 2025-09-18 Yulia Pimonova , Michael G. Taylor , Alice Allen , Ping Yang , Nicholas Lubbers

Chemical reaction networks (CRNs) provide a convenient language for modelling a broad variety of biological systems. These models are commonly studied with respect to the time series they generate in deterministic or stochastic simulations.…

Molecular Networks · Quantitative Biology 2019-07-11 Ozan Kahramanoğulları

Language modeling has seen impressive progress over the last years, mainly prompted by the invention of the Transformer architecture, sparking a revolution in many fields of machine learning, with breakthroughs in chemistry and biology. In…

Machine Learning · Computer Science 2023-10-11 Andres M Bran , Philippe Schwaller

Operating under real world conditions is challenging due to the possibility of a wide range of failures induced by execution errors and state uncertainty. In relatively benign settings, such failures can be overcome by retrying or executing…

Robotics · Computer Science 2023-03-10 Shivam Vats , Maxim Likhachev , Oliver Kroemer