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Large Language Models (LLMs) have exhibited remarkable capabilities in clinical scenarios. Despite their potential, existing works face challenges when applying LLMs to medical settings. Strategies relying on training with medical datasets…

Computation and Language · Computer Science 2025-10-10 Keer Lu , Zheng Liang , Da Pan , Shusen Zhang , Guosheng Dong , Zhonghai Wu , Huang Leng , Bin Cui , Wentao Zhang

Empowered by vast internal knowledge reservoir, the new generation of large language models (LLMs) demonstrate untapped potential to tackle medical tasks. However, there is insufficient effort made towards summoning up a synergic effect…

Computation and Language · Computer Science 2025-05-23 Kexin Shang , Chia-Hsuan Chang , Christopher C. Yang

Although large language models (LLMs) often produce impressive outputs, it remains unclear how they perform in real-world scenarios requiring strong reasoning skills and expert domain knowledge. We set out to investigate whether close- and…

Computation and Language · Computer Science 2023-12-27 Valentin Liévin , Christoffer Egeberg Hother , Andreas Geert Motzfeldt , Ole Winther

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Large language models (LLMs) typically enhance their performance through either the retrieval of semantically similar information or the improvement of their reasoning capabilities. However, a significant challenge remains in effectively…

Artificial Intelligence · Computer Science 2026-01-05 Shuqi Liu , Bowei He , Chen Ma , Linqi Song

Large Language Models (LLMs) have demonstrated remarkable versatility in recent years, offering potential applications across specialized domains such as healthcare and medicine. Despite the availability of various open-source LLMs tailored…

Computation and Language · Computer Science 2024-07-18 Yanis Labrak , Adrien Bazoge , Emmanuel Morin , Pierre-Antoine Gourraud , Mickael Rouvier , Richard Dufour

This study evaluates the performance of several Large Language Models (LLMs) on MedRedQA, a dataset of consumer-based medical questions and answers by verified experts extracted from the AskDocs subreddit. While LLMs have shown proficiency…

Computation and Language · Computer Science 2025-01-03 Moaiz Abrar , Yusuf Sermet , Ibrahim Demir

Large Language Models (LLMs) have demonstrated amazing capabilities in language generation, text comprehension, and knowledge reasoning. While a single powerful model can already handle multiple tasks, relying on a single perspective can…

Computation and Language · Computer Science 2024-06-12 Zining Qin , Chenhao Wang , Huiling Qin , Weijia Jia

Large language models (LLMs) have shown impressive capabilities across a wide range of language tasks. However, their reasoning process is primarily guided by statistical patterns in training data, which limits their ability to handle novel…

Artificial Intelligence · Computer Science 2025-08-21 Hong Su

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Biomedical text mining and question-answering are essential yet highly demanding tasks, particularly in the face of the exponential growth of biomedical literature. In this work, we present our participation in the 13th edition of the…

Computation and Language · Computer Science 2025-08-05 Dimitra Panou , Alexandros C. Dimopoulos , Manolis Koubarakis , Martin Reczko

Large Language Models (LLMs) have shown strong performance on static medical Question Answering (QA) tasks, yet their reasoning often deteriorates in multi-turn clinical dialogues where patient information is scattered across turns. This…

Computation and Language · Computer Science 2025-10-15 Zhaohan Meng , Zaiqiao Meng , Siwei Liu , Iadh Ounis

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

The growing use of large language models (LLMs) for biomedical question answering raises concerns about the accuracy and evidentiary support of their responses. To address this, we present Answered with Evidence, a framework for evaluating…

Machine Learning · Computer Science 2025-07-08 Julian D Baldwin , Christina Dinh , Arjun Mukerji , Neil Sanghavi , Saurabh Gombar

Large language models (LLMs), particularly those with reasoning capabilities, have rapidly advanced in recent years, demonstrating significant potential across a wide range of applications. However, their deployment in healthcare,…

Artificial Intelligence · Computer Science 2025-02-27 Guoxin Wang , Minyu Gao , Shuai Yang , Ya Zhang , Lizhi He , Liang Huang , Hanlin Xiao , Yexuan Zhang , Wanyue Li , Lu Chen , Jintao Fei , Xin Li

The growing capabilities of Large Language Models (LLMs) show significant potential to enhance healthcare by assisting medical researchers and physicians. However, their reliance on static training data is a major risk when medical…

Computation and Language · Computer Science 2025-09-05 Juraj Vladika , Mahdi Dhaini , Florian Matthes

While increasing patients' access to medical documents improves medical care, this benefit is limited by varying health literacy levels and complex medical terminology. Large language models (LLMs) offer solutions by simplifying medical…

Computation and Language · Computer Science 2025-02-06 Amin Dada , Osman Alperen Koras , Marie Bauer , Amanda Butler , Kaleb E. Smith , Jens Kleesiek , Julian Friedrich

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Recent large language models (LLMs) have advanced table understanding capabilities but rely on converting tables into text sequences. While multimodal large language models (MLLMs) enable direct visual processing, they face limitations in…

Computation and Language · Computer Science 2025-02-26 Bohao Yang , Yingji Zhang , Dong Liu , André Freitas , Chenghua Lin