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What is a systematic way to efficiently apply a wide spectrum of advanced ML programs to industrial scale problems, using Big Models (up to 100s of billions of parameters) on Big Data (up to terabytes or petabytes)? Modern parallelization…

High throughput experimentation tools, machine learning (ML) methods, and open material databases are radically changing the way new materials are discovered. From the experimentally driven approach in the past, we are moving quickly…

Materials Science · Physics 2025-08-06 Albertus Denny Handoko , Riko I Made

Transformer neural networks show promising capabilities, in particular for uses in materials analysis, design and manufacturing, including their capacity to work effectively with both human language, symbols, code, and numerical data. Here…

Computation and Language · Computer Science 2023-11-01 Markus J. Buehler

Large language model (LLM)--based agents have emerged as pivotal tools in assisting human experts across various fields by transforming complex tasks into more efficient workflows and providing actionable stakeholder insights. Despite their…

Human-Computer Interaction · Computer Science 2025-05-13 Xiaoshan Huang , Jie Gao , Haolun Wu

Language modeling has seen impressive progress over the last years, mainly prompted by the invention of the Transformer architecture, sparking a revolution in many fields of machine learning, with breakthroughs in chemistry and biology. In…

Machine Learning · Computer Science 2023-10-11 Andres M Bran , Philippe Schwaller

Predicting molecular properties is a critical component of drug discovery. Recent advances in deep learning, particularly Graph Neural Networks (GNNs), have enabled end-to-end learning from molecular structures, reducing reliance on manual…

Computation and Language · Computer Science 2025-09-26 Peng Zhou , Lai Hou Tim , Zhixiang Cheng , Kun Xie , Chaoyi Li , Wei Liu , Xiangxiang Zeng

Social media platforms such as Instagram and Twitter have emerged as critical channels for drug marketing and illegal sale. Detecting and labeling online illicit drug trafficking activities becomes important in addressing this issue.…

Computation and Language · Computer Science 2023-07-10 Chuanbo Hu , Bin Liu , Xin Li , Yanfang Ye

AI agents powered by large language models (LLMs) have shown strong capabilities in problem solving. Through combining many intelligent agents, multi-agent collaboration has emerged as a promising approach to tackle complex, multi-faceted…

Computation and Language · Computer Science 2024-12-10 Raphael Shu , Nilaksh Das , Michelle Yuan , Monica Sunkara , Yi Zhang

Building effective machine learning (ML) workflows to address complex tasks is a primary focus of the Automatic ML (AutoML) community and a critical step toward achieving artificial general intelligence (AGI). Recently, the integration of…

Machine Learning · Computer Science 2024-12-30 Yang Gu , Hengyu You , Jian Cao , Muran Yu , Haoran Fan , Shiyou Qian

Large language models (LLMs) are useful tools with the capacity for performing specific types of knowledge work at an effective scale. However, LLM deployments in high-risk and safety-critical domains pose unique challenges, notably the…

Computation and Language · Computer Science 2024-09-05 Joe B Hakim , Jeffery L Painter , Darmendra Ramcharran , Vijay Kara , Greg Powell , Paulina Sobczak , Chiho Sato , Andrew Bate , Andrew Beam

Text-guided molecule generation is a task where molecules are generated to match specific textual descriptions. Recently, most existing SMILES-based molecule generation methods rely on an autoregressive architecture. In this work, we…

Machine Learning · Computer Science 2024-02-21 Haisong Gong , Qiang Liu , Shu Wu , Liang Wang

Large language models (LLMs) struggle to effectively utilize a growing number of external tools, such as those defined by the Model Context Protocol (MCP)\cite{IntroducingMCP}, due to prompt bloat and selection complexity. We introduce…

Artificial Intelligence · Computer Science 2025-05-07 Tiantian Gan , Qiyao Sun

Large language models (LLMs) have become central to modern AI workflows, powering applications from open-ended text generation to complex agent-based reasoning. However, debugging these models remains a persistent challenge due to their…

Machine learning has huge potential to revolutionize the field of drug discovery and is attracting increasing attention in recent years. However, lacking domain knowledge (e.g., which tasks to work on), standard benchmarks and data…

Artificial intelligence (AI) methods have become critical in scientific applications to help accelerate scientific discovery. Large language models (LLMs) are being considered as a promising approach to address some of the challenging…

Molecular dynamics (MD) simulations are essential for understanding biomolecular systems but remain challenging to automate. Recent advances in large language models (LLM) have demonstrated success in automating complex scientific tasks…

Artificial Intelligence · Computer Science 2025-02-14 Quintina Campbell , Sam Cox , Jorge Medina , Brittany Watterson , Andrew D. White

Use case modeling employs user-centered scenarios to outline system requirements. These help to achieve consensus among relevant stakeholders. Because the manual creation of use case models is demanding and time-consuming, it is often…

Software Engineering · Computer Science 2025-11-14 Tobias Eisenreich , Nicholas Friedlaender , Stefan Wagner

Drug discovery is a complex, multi-step pipeline that remains heavily dependent on manual, experience-driven operations; meanwhile, existing customized artificial intelligence tools are fragmented across web applications, desktop software,…

Biomolecules · Quantitative Biology 2026-03-03 Qihua Pan , Dong Xu , Qianwei Yang , Jenna Xinyi Yao , Sisi Yuan , Zexuan Zhu , Jianqiang Li , Junkai Ji

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

This paper presents the development of an AI powered software platform that leverages advanced large language models (LLMs) to transform technology scouting and solution discovery in industrial R&D. Traditional approaches to solving complex…

Artificial Intelligence · Computer Science 2025-11-28 Manish Verma , Vivek Sharma , Vishal Singh
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