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The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…

Score-based methods have recently seen increasing popularity in modeling and generation. Methods have been constructed to perform hypothesis testing and change-point detection with score functions, but these methods are in general not as…

Machine Learning · Statistics 2025-06-23 Sean Moushegian , Taposh Banerjee , Vahid Tarokh

Bayesian methods are appealing in their flexibility in modeling complex data and ability in capturing uncertainty in parameters. However, when Bayes' rule does not result in tractable closed-form, most approximate inference algorithms lack…

Machine Learning · Computer Science 2016-05-09 Bo Dai , Niao He , Hanjun Dai , Le Song

The proliferation of early diagnostic technologies, including self-monitoring systems and wearables, coupled with the application of these technologies on large segments of healthy populations may significantly aggravate the problem of…

Machine Learning · Computer Science 2021-07-23 Anna Fedyukova , Douglas Pires , Daniel Capurro

Despite significant advances in particle imaging technologies over the past two decades, few advances have been made in particle tracking, i.e. linking individual particle positions across time series data. The state-of-the-art tracking…

Soft Condensed Matter · Physics 2022-01-25 Ella M. King , Zizhao Wang , David A. Weitz , Frans Spaepen , Michael P. Brenner

Particle tracking is common in many biophysical, ecological, and micro-fluidic applications. Reliable tracking information is heavily dependent on of the system under study and algorithms that correctly determines particle position between…

Computer Vision and Pattern Recognition · Computer Science 2016-05-12 Alvaro Rodriguez , Hanqing Zhang , Krister Wiklund , Tomas Brodin , Jonatan Klaminder , Patrik Andersson , Magnus Andersson

Driven by single photon detection requirements especially for quantum information sciences, the theory of arrays of off-on detectors has been well developed and applied. However for a comprehensive characterization of nonclassicality one…

Quantum Physics · Physics 2015-02-16 J. Sperling , W. Vogel , G. S. Agarwal

Digital pathology plays a vital role across modern medicine, offering critical insights for disease diagnosis, prognosis, and treatment. However, histopathology images often contain artifacts introduced during slide preparation and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Zhenzhen Wang , Zhongliang Zhou , Zhuoyu Wen , Jeong Hwan Kook , John B Wojcik , John Kang

Recent progress in generative models has made it easier for a wide audience to edit and create image content, raising concerns about the proliferation of deepfakes, especially in healthcare. Despite the availability of numerous techniques…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Fred Grabovski , Lior Yasur , Guy Amit , Yisroel Mirsky

We propose digital-analog quantum kernels for enhancing the detection of complex features in the classification of images. We consider multipartite-entangled analog blocks, stemming from native Ising interactions in neutral-atom quantum…

The development of molecular diagnostic tools to achieve individualized medicine requires identifying predictive biomarkers associated with subgroups of individuals who might receive beneficial or harmful effects from different available…

Methodology · Statistics 2020-01-20 Shonosuke Sugasawa , Hisashi Noma

Quantum hypothesis testing is one of the most fundamental problems in quantum information theory, with crucial implications in areas like quantum sensing, where it has been used to prove quantum advantage in a series of binary photonic…

Quantum Physics · Physics 2020-12-10 Leonardo Banchi , Quntao Zhuang , Stefano Pirandola

A major bottleneck in nanoparticle measurements is the lack of comparability. Comparability of measurement results is obtained by metrological traceability, which is obtained by calibration. In the present work the calibration of…

Applications · Statistics 2018-12-24 J. Pétry , B. De Boeck , N. Sebaihi , M. Coenegrachts , T. Caebergs , M. Dobre

One of the challenges facing the adoption of digital pathology workflows for clinical use is the need for automated quality control. As the scanners sometimes determine focus inaccurately, the resultant image blur deteriorates the scanned…

Image and Video Processing · Electrical Eng. & Systems 2018-11-16 Mahdi S. Hosseini , Yueyang Zhang , Lyndon Chan , Konstantinos N. Plataniotis , Jasper A. Z. Brawley-Hayes , Savvas Damaskinos

Light scattering detection in the near field, a rapidly expanding family of scattering techniques, has recently proved to be an appropriate procedure for performing dynamic measurements. Here we report an innovative algorithm, based on the…

This paper proposes a belief propagation (BP)-based algorithm for sequential detection and estimation of multipath component (MPC) parameters based on radio signals. Under dynamic channel conditions with moving transmitter/receiver, the…

Information Theory · Computer Science 2022-05-24 Xuhong Li , Erik Leitinger , Alexander Venus , Fredrik Tufvesson

Our article deals with Bayesian inference for a general state space model with the simulated likelihood computed by the particle filter. We show empirically that the partially or fully adapted particle filters can be much more efficient…

Methodology · Statistics 2010-06-11 Michael Pitt , Ralph Silva , Paolo Giordani , Robert Kohn

Shape-valued data are of interest in applied sciences, particularly in medical imaging. In this paper, inspired by a specific medical imaging example, we introduce a hypothesis testing method via the smooth Euler characteristic transform to…

Methodology · Statistics 2023-08-15 Jinyu Wang , Kun Meng , Fenghai Duan

Controlling crystalline material defects is crucial, as they affect properties of the material that may be detrimental or beneficial for the final performance of a device. Defect analysis on the sub-nanometer scale is enabled by…

Materials Science · Physics 2021-06-03 Nik Dennler , Antonio Foncubierta-Rodriguez , Titus Neupert , Marilyne Sousa

Liquid chromatography with tandem mass spectrometry (LC-MS/MS) based proteomics is a well-established research field with major applications such as identification of disease biomarkers, drug discovery, drug design and development. In…

Quantitative Methods · Quantitative Biology 2018-01-08 Fatema Tuz Zohora , Ngoc Hieu Tran , Xianglilan Zhang , Lei Xin , Baozhen Shan , Ming Li