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The diverse nature of protein prediction tasks has traditionally necessitated specialized models, hindering the development of broadly applicable and computationally efficient Protein Language Models (PLMs). In this work, we introduce…

With the rapid development of deep learning, existing generative text steganography methods based on autoregressive models have achieved success. However, these autoregressive steganography approaches have certain limitations. Firstly,…

Cryptography and Security · Computer Science 2025-04-29 Zhengxian Wu , Juan Wen , Yiming Xue , Ziwei Zhang , Yinghan Zhou

While machine learning models are typically trained to solve prediction problems, we might often want to use them for optimization problems. For example, given a dataset of proteins and their corresponding fluorescence levels, we might want…

Machine Learning · Computer Science 2024-10-18 Jakub Grudzien Kuba , Masatoshi Uehara , Pieter Abbeel , Sergey Levine

Protein structure prediction and folding are fundamental to understanding biology, with recent deep learning advances reshaping the field. Diffusion-based generative models have revolutionized protein design, enabling the creation of novel…

Machine Learning · Computer Science 2025-10-01 Yogesh Verma , Markus Heinonen , Vikas Garg

Proteins employ the information stored in the genetic code and translated into their sequences to carry out well-defined functions in the cellular environment. The possibility to encode for such functions is controlled by the balance…

Biomolecules · Quantitative Biology 2018-05-24 A. Possenti , M. Vendruscolo , C. Camilloni , G. Tiana

We introduce STAR, a text-to-image model that employs a scale-wise auto-regressive paradigm. Unlike VAR, which is constrained to class-conditioned synthesis for images up to 256$\times$256, STAR enables text-driven image generation up to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Xiaoxiao Ma , Mohan Zhou , Tao Liang , Yalong Bai , Tiejun Zhao , Biye Li , Huaian Chen , Yi Jin

Recent advances in large language models (LLMs) have highlighted the effectiveness of chain-of-thought reasoning in symbolic domains such as mathematics and programming. However, our study shows that directly transferring such text-based…

Artificial Intelligence · Computer Science 2026-03-06 Chuanliu Fan , Zicheng Ma , Huanran Meng , Aijia Zhang , Wenjie Du , Jun Zhang , Yi Qin Gao , Ziqiang Cao , Guohong Fu

While spatial transcriptomics (ST) has advanced our understanding of gene expression in tissue context, its high experimental cost limits its large-scale application. Predicting ST from pathology images is a promising, cost-effective…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Zhiceng Shi , Changmiao Wang , Jun Wan , Wenwen Min

Scene understanding is paramount in robotics, self-navigation, augmented reality, and many other fields. To fully accomplish this task, an autonomous agent has to infer the 3D structure of the sensed scene (to know where it looks at) and…

Computer Vision and Pattern Recognition · Computer Science 2020-02-26 Pier Luigi Dovesi , Matteo Poggi , Lorenzo Andraghetti , Miquel Martí , Hedvig Kjellström , Alessandro Pieropan , Stefano Mattoccia

Effective biomedical data integration depends on automated term normalization, the mapping of natural language biomedical terms to standardized identifiers. This linking of terms to identifiers is essential for semantic interoperability.…

Computation and Language · Computer Science 2025-10-23 Suswitha Pericharla , Daniel B. Hier , Tayo Obafemi-Ajayi

A critical step in sharing semantic content online is to map the structural data source to a public domain ontology. This problem is denoted as the Relational-To-Ontology Mapping Problem (Rel2Onto). A huge effort and expertise are required…

Artificial Intelligence · Computer Science 2022-12-22 Jiakang Xu , Wolfgang Mayer , HongYu Zhang , Keqing He , Zaiwen Feng

While deep learning has achieved great success in many fields, one common criticism about deep learning is its lack of interpretability. In most cases, the hidden units in a deep neural network do not have a clear semantic meaning or…

Genomics · Quantitative Biology 2019-06-04 Tianle Ma , Aidong Zhang

Protein structure tokenizers (PSTs) are workhorses in protein language modeling, function prediction, and evolutionary analysis. However, existing PSTs only capture local geometry of static structures, and miss the correlated motions and…

Machine Learning · Computer Science 2026-05-15 Kaiwen Shi , Carlos Oliver

In today's fast-evolving business landscape, having insight into the technology stacks that organizations use is crucial for forging partnerships, uncovering market openings, and informing strategic choices. However, conventional technology…

Information Retrieval · Computer Science 2025-01-28 Minh Hieu Nguyen , Hien Thu Pham , Hiep Minh Ha , Ngoc Quang Hung Le , Jun Jo

Generating step-by-step "chain-of-thought" rationales has proven effective for improving the performance of large language models on complex reasoning tasks. However, applying such techniques to structured tasks, such as text-to-SQL,…

Computation and Language · Computer Science 2025-02-20 Mingqian He , Yongliang Shen , Wenqi Zhang , Qiuying Peng , Jun Wang , Weiming Lu

Recent advances in Artificial Intelligence have enabled multi-modal systems to model and translate diverse information spaces. Extending beyond text and vision, we introduce OneProt, a multi-modal AI for proteins that integrates structural,…

Many platforms for benchmarking optimization algorithms offer users the possibility of sharing their experimental data with the purpose of promoting reproducible and reusable research. However, different platforms use different data models…

Neural and Evolutionary Computing · Computer Science 2021-04-27 Ana Kostovska , Diederick Vermetten , Carola Doerr , Sašo Džeroski , Panče Panov , Tome Eftimov

We introduce "pointer-guided segment ordering" (SO), a novel pre-training technique aimed at enhancing the contextual understanding of paragraph-level text representations in large language models. Our methodology leverages a…

Computation and Language · Computer Science 2024-06-07 Lars Hillebrand , Prabhupad Pradhan , Christian Bauckhage , Rafet Sifa

Many optimization algorithm benchmarking platforms allow users to share their experimental data to promote reproducible and reusable research. However, different platforms use different data models and formats, which drastically complicates…

Artificial Intelligence · Computer Science 2022-11-22 Ana Kostovska , Diederick Vermetten , Carola Doerr , Saso Džeroski , Panče Panov , Tome Eftimov

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

Machine Learning · Computer Science 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal