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To produce accurate predictions, language models (LMs) must balance between generalization and memorization. Yet, little is known about the mechanism by which transformer LMs employ their memorization capacity. When does a model decide to…

Computation and Language · Computer Science 2023-02-14 Adi Haviv , Ido Cohen , Jacob Gidron , Roei Schuster , Yoav Goldberg , Mor Geva

We present and evaluate a method called grammar masking, which is used to guide large language models (LLMs) toward producing syntactically correct models for a given context-free grammar. Prompt engineering methods such as few-shot…

Computation and Language · Computer Science 2024-07-10 Lukas Netz , Jan Reimer , Bernhard Rumpe

Most machine translation systems generate text autoregressively from left to right. We, instead, use a masked language modeling objective to train a model to predict any subset of the target words, conditioned on both the input text and a…

Computation and Language · Computer Science 2019-09-05 Marjan Ghazvininejad , Omer Levy , Yinhan Liu , Luke Zettlemoyer

In drug-discovery-related tasks such as virtual screening, machine learning is emerging as a promising way to predict molecular properties. Conventionally, molecular fingerprints (numerical representations of molecules) are calculated…

Machine Learning · Computer Science 2019-11-13 Shion Honda , Shoi Shi , Hiroki R. Ueda

Polymers, composed of repeating structural units called monomers, are fundamental materials in daily life and industry. Accurate property prediction for polymers is essential for their design, development, and application. However, existing…

Machine Learning · Computer Science 2025-07-29 Jiaxi Wang , Yaosen Min , Xun Zhu , Miao Li , Ji Wu

Retrosynthesis is the process of recursively decomposing target molecules into available building blocks. It plays an important role in solving problems in organic synthesis planning. To automate or assist in the retrosynthesis analysis,…

Quantitative Methods · Quantitative Biology 2020-11-06 Chaochao Yan , Qianggang Ding , Peilin Zhao , Shuangjia Zheng , Jinyu Yang , Yang Yu , Junzhou Huang

Synthetic polymeric materials underpin fundamental technologies in the energy, electronics, consumer goods, and medical sectors, yet their development still suffers from prolonged design timelines. Although polymer informatics tools have…

Computational Engineering, Finance, and Science · Computer Science 2025-06-12 Ayush Jain , Rampi Ramprasad

Traditional Large Language Model (LLM) pretraining relies on autoregressive language modeling with randomly sampled data from web-scale datasets. Inspired by human learning techniques like spaced repetition, we hypothesize that random…

Computation and Language · Computer Science 2025-01-30 Neha Prakriya , Jui-Nan Yen , Cho-Jui Hsieh , Jason Cong

Most language models (LMs) are trained and applied in an autoregressive left-to-right fashion, assuming that the next token only depends on the preceding ones. However, this assumption ignores the potential benefits of using the full…

Computation and Language · Computer Science 2023-03-14 Anh Nguyen , Nikos Karampatziakis , Weizhu Chen

Conventional mechanical design follows an iterative process in which initial concepts are refined through cycles of expert assessment and resource-intensive Finite Element Method (FEM) analysis to meet performance goals. While machine…

Machine Learning · Computer Science 2025-05-02 Yayati Jadhav , Amir Barati Farimani

We introduce a mathematical framework for retrosynthetic analysis, an important research method in synthetic chemistry. Our approach represents molecules and their interaction using string diagrams in layered props - a recently introduced…

Logic in Computer Science · Computer Science 2023-11-08 Ella Gale , Leo Lobski , Fabio Zanasi

Large Language Models (LLMs) have recently garnered significant attention, primarily for their capabilities in text-based interactions. However, natural human interaction often relies on speech, necessitating a shift towards voice-based…

Computation and Language · Computer Science 2025-08-08 Wenqian Cui , Dianzhi Yu , Xiaoqi Jiao , Ziqiao Meng , Guangyan Zhang , Qichao Wang , Yiwen Guo , Irwin King

While pretrained language models (PLMs) primarily serve as general-purpose text encoders that can be fine-tuned for a wide variety of downstream tasks, recent work has shown that they can also be rewired to produce high-quality word…

Computation and Language · Computer Science 2023-05-30 Tommaso Green , Simone Paolo Ponzetto , Goran Glavaš

Term-based sparse representations dominate the first-stage text retrieval in industrial applications, due to its advantage in efficiency, interpretability, and exact term matching. In this paper, we study the problem of transferring the…

Information Retrieval · Computer Science 2020-10-05 Yang Bai , Xiaoguang Li , Gang Wang , Chaoliang Zhang , Lifeng Shang , Jun Xu , Zhaowei Wang , Fangshan Wang , Qun Liu

Retrosynthesis is a technique to plan the chemical synthesis of organic molecules, for example drugs, agro- and fine chemicals. In retrosynthesis, a search tree is built by analysing molecules recursively and dissecting them into simpler…

Artificial Intelligence · Computer Science 2017-02-02 Marwin Segler , Mike Preuß , Mark P. Waller

This study investigates the capabilities of Large Language Models (LLMs), specifically GPT-4, in the context of Binary Reverse Engineering (RE). Employing a structured experimental approach, we analyzed the LLM's performance in interpreting…

Software Engineering · Computer Science 2024-06-12 Saman Pordanesh , Benjamin Tan

Large Language models (LLMs) have shown promise as generators of symbolic control policies, producing interpretable program-like representations through iterative search. However, these models are not capable of separating the functional…

Machine Learning · Computer Science 2025-10-02 Carlo Bosio , Matteo Guarrera , Alberto Sangiovanni-Vincentelli , Mark W. Mueller

Can we leverage LLMs to model the process of discovering novel language model (LM) architectures? Inspired by real research, we propose a multi-agent LLM approach that simulates the conventional stages of research, from ideation and…

Artificial Intelligence · Computer Science 2025-06-26 Junyan Cheng , Peter Clark , Kyle Richardson

Models based on machine learning can enable accurate and fast molecular property predictions, which is of interest in drug discovery and material design. Various supervised machine learning models have demonstrated promising performance,…

Machine Learning · Computer Science 2022-12-15 Jerret Ross , Brian Belgodere , Vijil Chenthamarakshan , Inkit Padhi , Youssef Mroueh , Payel Das

Retrieval-augmented language models (LMs) have received much attention recently. However, typically the retriever is not trained jointly as a native component of the LM, but added post-hoc to an already-pretrained LM, which limits the…

Computation and Language · Computer Science 2024-07-23 Ohad Rubin , Jonathan Berant