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Large Language Models (LLMs) have emerged as promising solutions for a variety of medical and clinical decision support applications. However, LLMs are often subject to different types of biases, which can lead to unfair treatment of…

In the rapidly evolving AI era with large language models (LLMs) at the core, making LLMs more trustworthy and efficient, especially in output generation (inference), has gained significant attention. This is to reduce plausible but faulty…

The development of AI agents based on large, open-domain language models (LLMs) has paved the way for the development of general-purpose AI assistants that can support human in tasks such as writing, coding, graphic design, and scientific…

Large Language Models (LLMs) have shown significant advances in text generation but often lack the reliability needed for autonomous deployment in high-stakes domains like healthcare, law, and finance. Existing approaches rely on external…

With the recent development of natural language generation models - termed as large language models (LLMs) - a potential use case has opened up to improve the way that humans interact with robot assistants. These LLMs should be able to…

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

This position paper argues that in many realistic (i.e., complex, contextualized, subjective) scenarios, one LLM is not enough to produce a reliable output. We challenge the status quo of relying solely on a single general-purpose LLM and…

Large Language Models (LLMs) are widely used in critical fields such as healthcare, education, and finance due to their remarkable proficiency in various language-related tasks. However, LLMs are prone to generating factually incorrect…

While humans increasingly rely on large language models (LLMs), they are susceptible to generating inaccurate or false information, also known as "hallucinations". Technical advancements have been made in algorithms that detect hallucinated…

As Large Language Models (LLMs) get integrated into diverse workflows, they are increasingly being regarded as "collaborators" with humans, and required to work in coordination with other AI systems. If such AI collaborators are to reliably…

Large Language Models (LLMs) have emerged as a transformative AI paradigm, profoundly influencing daily life through their exceptional language understanding and contextual generation capabilities. Despite their remarkable performance, LLMs…

As Large Language Models become integral to decision-making, optimism about their power is tempered with concern over their errors. Users may over-rely on LLM advice that is confidently stated but wrong, or under-rely due to mistrust.…

Recent years have witnessed a surge of research on leveraging large language models (LLMs) for sequential recommendation. LLMs have demonstrated remarkable potential in inferring users' nuanced preferences through fine-grained semantic…

The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

This paper explores the evolving relationship between clinician trust in LLMs, the transformation of data sources from predominantly human-generated to AI-generated content, and the subsequent impact on the precision of LLMs and clinician…

The drug development process necessitates that pharmacologists undertake various tasks, such as reviewing literature, formulating hypotheses, designing experiments, and interpreting results. Each stage requires accessing and querying vast…

The global mental health crisis is looming with a rapid increase in mental disorders, limited resources, and the social stigma of seeking treatment. As the field of artificial intelligence (AI) has witnessed significant advancements in…

Multimodal artificial intelligence (AI) systems have the potential to enhance clinical decision-making by interpreting various types of medical data. However, the effectiveness of these models across all medical fields is uncertain. Each…

Large language models (LLMs) exhibit extensive medical knowledge but are prone to hallucinations and inaccurate citations, which pose a challenge to their clinical adoption and regulatory compliance. Current methods, such as Retrieval…

With the rapid progress of Large Language Models (LLMs), the general public now has easy and affordable access to applications capable of answering most health-related questions in a personalized manner. These LLMs are increasingly proving…