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Neural population activity often exhibits rich variability and temporal structure. This variability is thought to arise from single-neuron stochasticity, neural dynamics on short time-scales, as well as from modulations of neural firing…

Machine Learning · Statistics 2014-10-14 Mijung Park , Jakob H. Macke

Response variability, as measured by fluctuating responses upon repeated performance of trials, is a major component of neural responses, and its characterization is key to interpret high dimensional population recordings. Response…

Neurons and Cognition · Quantitative Biology 2016-05-31 Mihály Bányai , Zsombor Koman , Gergő Orbán

In many areas of the brain, neural spiking activity covaries with features of the external world, such as sensory stimuli or an animal's movement. Experimental findings suggest that the variability of neural activity changes over time and…

Neurons and Cognition · Quantitative Biology 2022-10-11 Ganchao Wei , Ian H. Stevenson

The neural activity in the visual processing is influenced by both external stimuli and internal brain states. Ideally, a neural predictive model should account for both of them. Currently, there are no dynamic encoding models that…

Neurons and Cognition · Quantitative Biology 2025-11-18 Finn Schmidt , Polina Turishcheva , Suhas Shrinivasan , Fabian H. Sinz

An essential step toward understanding neural circuits is linking their structure and their dynamics. In general, this relationship can be almost arbitrarily complex. Recent theoretical work has, however, begun to identify some broad…

Neurons and Cognition · Quantitative Biology 2017-03-10 Gabriel Koch Ocker , Yu Hu , Michael A. Buice , Brent Doiron , Krešimir Josić , Robert Rosenbaum , Eric Shea-Brown

Understanding the activity of large populations of neurons is difficult due to the combinatorial complexity of possible cell-cell interactions. To reduce the complexity, coarse-graining had been previously applied to experimental neural…

Neurons and Cognition · Quantitative Biology 2021-03-24 Mia C. Morrell , Audrey J. Sederberg , Ilya Nemenman

Previous studies have demonstrated the importance of the primary sensory cortex for the detection, discrimination and awareness of visual stimuli, but it is unknown how neuronal populations in this area process detected and undetected…

Neurons and Cognition · Quantitative Biology 2015-12-03 Jorrit S. Montijn , Pieter M. Goltstein , Cyriel M. A. Pennartz

Sensory neurons often have variable responses to repeated presentations of the same stimulus, which can significantly degrade the stimulus information contained in those responses. This information can in principle be preserved if…

Neurons and Cognition · Quantitative Biology 2019-04-24 Matthew R Whiteway , Karolina Socha , Vincent Bonin , Daniel A Butts

Individual neurons often produce highly variable responses over nominally identical trials, reflecting a mixture of intrinsic "noise" and systematic changes in the animal's cognitive and behavioral state. Disentangling these sources of…

Neurons and Cognition · Quantitative Biology 2021-11-08 Alex H. Williams , Scott W. Linderman

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

The brain works as a dynamic system to process information. Various challenges remain in understanding the connection between information and dynamics attributes in the brain. The present research pursues exploring how the characteristics…

Neurons and Cognition · Quantitative Biology 2022-07-14 Yang Tian , Guoqi Li , Pei Sun

Generative models of brain activity have been instrumental in testing hypothesized mechanisms underlying brain dynamics against experimental datasets. Beyond capturing the key mechanisms underlying spontaneous brain dynamics, these models…

Neurons and Cognition · Quantitative Biology 2024-11-18 Rishikesan Maran , Eli J. Müller , Ben D. Fulcher

The correlated variability in the responses of a neural population to the repeated presentation of a sensory stimulus is a universally observed phenomenon. Such correlations have been studied in much detail, both with respect to their…

Neurons and Cognition · Quantitative Biology 2018-07-04 Volker Pernice , Rava Azeredo da Silveira

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

Even when driven by the same stimulus, neuronal responses are well-known to exhibit a striking level of spiking variability. In-vivo electrophysiological recordings also reveal a surprisingly large degree of variability at the subthreshold…

Neurons and Cognition · Quantitative Biology 2025-03-19 Logan A. Becker , Francois Baccelli , Thibaud Taillefumier

We explore the interplay between the topological relevance of a neuron and its dynamical traces in experimental cultured neuronal networks. We monitor the growth and development of these networks to characterise the evolution of their…

Adaptation and Self-Organizing Systems · Physics 2023-07-14 A. Tlaie , L. M. Ballesteros-Esteban , I. Leyva , I. Sendina-Nadal

As experiments advance to record from tens of thousands of neurons, statistical physics provides a framework for understanding how collective activity emerges from networks of fine-scale correlations. While modeling these populations is…

Biological Physics · Physics 2024-12-25 David P. Carcamo , Christopher W. Lynn

Brain decoding involves the determination of a subject's cognitive state or an associated stimulus from functional neuroimaging data measuring brain activity. In this setting the cognitive state is typically characterized by an element of a…

Machine Learning · Statistics 2015-04-14 Nicole Croteau , Farouk S. Nathoo , Jiguo Cao , Ryan Budney

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of…

Neurons and Cognition · Quantitative Biology 2018-11-15 Kanika Bansal , John D. Medaglia , Danielle S. Bassett , Jean M. Vettel , Sarah F. Muldoon

The population model of Wilson-Cowan is perhaps the most popular in the history of computational neuroscience. It embraces the nonlinear mean field dynamics of excitatory and inhibitory neuronal populations provided via a temporal…

Neurons and Cognition · Quantitative Biology 2023-09-13 Maryam Saadati , Saba Sadat Khodaei , Yousef Jamali
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