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There is little doubt in scientific circles that--counting from the origin of life towards today--evolution has led to an increase in the amount of information stored within the genomes of the biosphere. This trend of increasing information…

Populations and Evolution · Quantitative Biology 2014-08-19 Masoud Mirmomeni , William F. Punch , Christoph Adami

We outline a phenomenological theory of evolution and origin of life by combining the formalism of classical thermodynamics with a statistical description of learning. The maximum entropy principle constrained by the requirement for…

Populations and Evolution · Quantitative Biology 2022-10-12 Vitaly Vanchurin , Yuri I. Wolf , Eugene V. Koonin , Mikhail I. Katsnelson

In a pioneering study experimental evidence was sought of thermosynthesis, a theoretical biological mechanism for free energy gain from thermal cycling that has been invoked as energy source for the origin of life. A PCR machine applied…

Biological Physics · Physics 2007-05-23 Anthonie W. J. Muller

It is a common belief that in any environment where life is possible, life will be generated. Here it is suggested that the cause for a spontaneous generation of complex systems is probability driven processes. Based on equilibrium…

Information Theory · Computer Science 2007-11-29 Oded Kafri

Living systems efficiently use chemical fuel to do work, process information, and assemble patterns despite thermal noise. Whether high efficiency arises from general principles or specific fine-tuning is unknown. Here, applying a recent…

Biological Physics · Physics 2022-10-11 Milo M Lin

According to conventional wisdom, a system placed in an environment with a different temperature tends to relax to the temperature of the latter, mediated by the flows of heat and/or matter that are set solely by the temperature difference.…

Statistical Mechanics · Physics 2024-03-18 Miguel Ibáñez , Cai Dieball , Antonio Lasanta , Aljaž Godec , Raúl A. Rica

The possibility that evolutionary forces -- together with a few fundamental factors such as thermodynamic constraints, specific computational features enabling information processing, and ecological processes -- might constrain the logic of…

Biological Physics · Physics 2025-12-30 Manlio De Domenico

Recently, plenty research has been done on discovering the role of energy dissipation in biological networks, most of which focus on the relationship of dissipation and functionality. However, the development of networks science urged us to…

Biological Physics · Physics 2026-05-20 Bowen Shi , Long Qian , Qi Ouyang

At any moment in time, evolution is faced with a formidable challenge: refining the already highly optimised design of biological species, a feat accomplished through all preceding generations. In such a scenario, the impact of random…

Populations and Evolution · Quantitative Biology 2024-02-20 Alessandro Fontana , Marios Kyriazis

An important feature of many complex systems, both natural and artificial, is the structure and organization of their interaction networks with interesting properties. Here we present a theory of self-organization by evolutionary adaptation…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Venkat Venkatasubramanian , Santhoji Katare , Priyan R. Patkar , Fangping Mu

Traditionally evolution is seen as a process where from a pool of possible variations of a population (e.g. biological species or industrial goods) a few variations get selected which survive and proliferate, whereas the others vanish.…

Populations and Evolution · Quantitative Biology 2008-09-25 Rudolf Hanel , Stefan Thurner

Situations where a spontaneous process of energy or matter transfer is enhanced by an external device are widespread in nature (human sweating system, enzyme catalysis, facilitated diffusion across bio-membranes, industrial heat…

Statistical Mechanics · Physics 2010-07-21 Karen Hovhannisyan , Armen E. Allahverdyan

The multifarious internal workings of organisms are difficult to reconcile with a single feature defining a state of being alive. Indeed, definitions of life rely on emergent properties (growth, capacity to evolve, agency) only symptomatic…

Other Quantitative Biology · Quantitative Biology 2023-08-16 Simon Pierce

Chemical processes in closed systems are poorly controllable since they always relax to equilibrium. Living systems avoid this fate and give rise to a much richer diversity of phenomena by operating under nonequilibrium conditions. Recent…

Chemical Physics · Physics 2019-09-11 Emanuele Penocchio , Riccardo Rao , Massimiliano Esposito

Metabolic reactions of single-cell organisms are routinely observed to become dispensable or even incapable of carrying activity under certain circumstances. Yet, the mechanisms as well as the range of conditions and phenotypes associated…

Molecular Networks · Quantitative Biology 2009-01-21 Takashi Nishikawa , Natali Gulbahce , Adilson E. Motter

The rapidly developing theory of complex networks indicates that real networks are not random, but have a highly robust large-scale architecture, governed by strict organizational principles. Here, we focus on the properties of biological…

Molecular Networks · Quantitative Biology 2007-05-23 E. Almaas , A. -L. Barabasi

Motivated by the wide range of known self-replicating systems, some far from genetics, we study a system composed by individuals having an internal dynamics with many possible states that are partially stable, with varying mutation rates.…

Biological Physics · Physics 2015-10-07 Tommaso Brotto , Guy Bunin , Jorge Kurchan

The composition of cellular metabolism is different across species. Empirical data reveal that bacterial species contain similar numbers of metabolic reactions but that the cross-species popularity of reactions is so heterogenous that some…

Populations and Evolution · Quantitative Biology 2024-01-08 Mi Jin Lee , Deok-Sun Lee

Metabolism and evolution are closely connected: if a mutation incurs extra energetic costs for an organism, there is a baseline selective disadvantage that may or may not be compensated for by other adaptive effects. A long-standing, but to…

Populations and Evolution · Quantitative Biology 2019-06-19 Efe Ilker , Michael Hinczewski

The energy dissipated by a living organism is commonly identified with heat generation. However, as cells exchange metabolites with their environment they also dissipate energy in the form of chemical entropy. How dissipation is distributed…

Other Quantitative Biology · Quantitative Biology 2025-10-09 Tommaso Cossetto , Jonathan Rodenfels , Pablo Sartori