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We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of ``stochastic feedback''. We illustrate this approach by considering the neuroautonomic regulation of the heart…

Statistical Mechanics · Physics 2009-10-30 Plamen Ch. Ivanov , Luis A. N. Amaral , Ary Goldberger , H. Eugene Stanley

Cortical oscillations are thought to be involved in many cognitive functions and processes. Several mechanisms have been proposed to regulate oscillations. One prominent but understudied mechanism is gap-junctional coupling. Gap junctions…

Neurons and Cognition · Quantitative Biology 2018-07-04 Guillaume Pernelle , Wilten Nicola , Claudia Clopath

Mounting evidence shows that oscillatory activity is widespread in cell signaling. Here we review some of this recent evidence, focusing on both the molecular mechanisms that potentially underlie such dynamical behavior, and the potential…

Cell Behavior · Quantitative Biology 2022-04-15 Pablo Casani-Galdon , Jordi Garcia-Ojalvo

Living systems self-organize in ways that conventional physical frameworks-based on forces, energies, and continuous fields-cannot fully capture. Processes like gene regulation and cellular decision-making involve rule-based logic and…

Other Quantitative Biology · Quantitative Biology 2025-11-18 Hyun Youk

Emergent communication protocols among humans and artificial neural network agents do not yet share the same properties and show some critical mismatches in results. We describe three important phenomena with respect to the emergence and…

Computation and Language · Computer Science 2022-04-25 Lukas Galke , Yoav Ram , Limor Raviv

Inspired by the observation of a distributed time delay in the nonlinear response of an optical resonator, we investigate the effects of a similar delay on a noise-driven mechanical oscillator. For a delay time that is commensurate with the…

Optics · Physics 2022-02-16 K. J. H. Peters , S. R. K. Rodriguez

A network of propagating nonlinear oscillatory modes (waves) in the human brain is shown to generate collectively synchronized spiking activity (hypersynchronous spiking) when both amplitude and phase coupling between modes are taken into…

Biological Physics · Physics 2021-04-28 Vitaly L. Galinsky , Lawrence R. Frank

Feedback control actively dissipates uncertainty from a dynamical system by means of actuation. We develop a notion of "control capacity" that gives a fundamental limit (in bits) on the rate at which a controller can dissipate the…

Information Theory · Computer Science 2017-01-17 Gireeja Ranade , Anant Sahai

Metaphors of Computation and Information tended to detract attention from the intrinsic modes of neural system functions, uncontaminated by the observer's role for collection and interpretation of experimental data. Recognizing the…

General Physics · Physics 2011-07-21 Gerhard Werner

Living systems regulate many aspects of their behavior through periodic oscillations of molecular concentrations, which function as `biochemical clocks.' These clocks are intrinsically subject to thermal fluctuations, so that the duration…

Biological Physics · Physics 2020-08-10 Robert Marsland , Wenping Cui , Jordan M. Horowitz

Recurrent neural policies are widely used in partially observable control and meta-RL tasks. Their abilities to maintain internal memory and adapt quickly to unseen scenarios have offered them unparalleled performance when compared to…

Machine Learning · Computer Science 2026-02-03 Jin Li , Yue Wu , Mengsha Huang , Yuhao Sun , Hao He , Xianyuan Zhan

We show that fluid organizations display higher levels of cooperation than attainable by groups with either a fixed social structure or lacking one altogether. By moving within the organization, individuals cause restructurings that…

chao-dyn · Physics 2008-02-03 Natalie Glance , Bernardo Huberman

Biological rhythms are generated by pacemaker organs, such as the heart pacemaker organ (the sinoatrial node) and the master clock of the circadian rhythms (the suprachiasmatic nucleus), which are composed of a network of autonomously…

Cell Behavior · Quantitative Biology 2016-08-23 Hiroshi Kori , Yoji Kawamura , Naoki Masuda

Shared upstream dynamical processes are frequently the source of common inputs in various physical and biological systems. However, due to finite signal transmission speeds and differences in the distance to the source, time shifts between…

Neurons and Cognition · Quantitative Biology 2017-03-10 Ehsan Bolhasani , Yousef Azizi , Alireza Valizadeh , Matjaz Perc

Collective oscillation of cells in a population has been reported under diverse biological contexts and with vastly different molecular constructs. Could there be common principles similar to those that govern spontaneous oscillation in…

Cell Behavior · Quantitative Biology 2019-07-08 Shou-Wen Wang , Lei-Han Tang

Self-organized criticality has been proposed to be a universal mechanism for the emergence of scale-free dynamics in many complex systems, and possibly in the brain. While such scale-free patterns were identified experimentally in many…

Neurons and Cognition · Quantitative Biology 2021-05-11 Roxana Zeraati , Viola Priesemann , Anna Levina

We study analytically the dynamics of a network of sparsely connected inhibitory integrate-and-fire neurons in a regime where individual neurons emit spikes irregularly and at a low rate. In the limit when the number of neurons N tends to…

Disordered Systems and Neural Networks · Physics 2007-05-23 N. Brunel , V. Hakim

Many cellular components are present in such low numbers that individual stochastic production and degradation events lead to significant fluctuations in molecular abundances. Although feedback control can, in principle, suppress such…

Molecular Networks · Quantitative Biology 2025-12-25 Ryan Ripsman , Brayden Kell , Andreas Hilfinger

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Neurons and Cognition · Quantitative Biology 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera
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