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Ultrasound microvascular imaging (UMI) is often hindered by low signal-to-noise ratio (SNR), especially in contrast-free or deep tissue scenarios, which impairs subsequent vascular quantification and reliable disease diagnosis. To address…

Purpose: To develop a fast, general-purpose framework for voxelwise noise characterization in linear and nonlinear iterative MRI reconstructions, recovering the image-domain noise variance from which SNR, $g$-factor, and related…

Signal Processing · Electrical Eng. & Systems 2026-05-12 Onat Dalmaz , Daniel Abraham , Alexander R. Toews , Akshay S. Chaudhari , Kawin Setsompop , Brian A. Hargreaves

The frequency difference between two oppositely propagating spin waves can be used to probe several interesting magnetic properties, such as the Dzyaloshinkii-Moriya interaction (DMI). Propagating spin wave spectroscopy is a technique that…

We introduce a framework that enables efficient sampling from learned probability distributions for MRI reconstruction. Different from conventional deep learning-based MRI reconstruction techniques, samples are drawn from the posterior…

Machine Learning · Computer Science 2023-07-21 Guanxiong Luo , Moritz Blumenthal , Martin Heide , Martin Uecker

We propose DoPAMINE, a new neural network based multiplicative noise despeckling algorithm. Our algorithm is inspired by Neural AIDE (N-AIDE), which is a recently proposed neural adaptive image denoiser. While the original N-AIDE was…

Image and Video Processing · Electrical Eng. & Systems 2019-02-08 Sunghwan Joo , Sungmin Cha , Taesup Moon

Robust principal component analysis (RPCA) can recover low-rank matrices when they are corrupted by sparse noises. In practice, many matrices are, however, of high-rank and hence cannot be recovered by RPCA. We propose a novel method called…

Machine Learning · Computer Science 2019-04-19 Jicong Fan , Tommy W. S. Chow

Purpose: This work proposes a novel self-supervised noise-adaptive image denoising framework, called Repetition to Repetition (Rep2Rep) learning, for low-field (<1T) MRI applications. Methods: Rep2Rep learning extends the Noise2Noise…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Nikola Janjušević , Jingjia Chen , Luke Ginocchio , Mary Bruno , Yuhui Huang , Yao Wang , Hersh Chandarana , Li Feng

Real-time Monte Carlo denoising aims at removing severe noise under low samples per pixel (spp) in a strict time budget. Recently, kernel-prediction methods use a neural network to predict each pixel's filtering kernel and have shown a…

Graphics · Computer Science 2022-02-28 Hangming Fan , Rui Wang , Yuchi Huo , Hujun Bao

Suppose we observe data of the form $Y_i = D_i (S_i + \varepsilon_i) \in \mathbb{R}^p$ or $Y_i = D_i S_i + \varepsilon_i \in \mathbb{R}^p$, $i=1,\ldots,n$, where $D_i \in \mathbb{R}^{p\times p}$ are known diagonal matrices, $\varepsilon_i$…

Statistics Theory · Mathematics 2018-11-05 Edgar Dobriban , William Leeb , Amit Singer

Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has…

Computer Vision and Pattern Recognition · Computer Science 2020-06-11 Sunghwan Yoo , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati

Current self-supervised denoising methods for paired noisy images typically involve mapping one noisy image through the network to the other noisy image. However, after measuring the spectral bias of such methods using our proposed Image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Wang Zhang , Huaqiu Li , Xiaowan Hu , Tao Jiang , Zikang Chen , Haoqian Wang

Structure-based drug design has been accelerated by pocket-aware 3D generative models, yet most methods primarily fit the training distribution and may fall short of satisfying multiple properties required in real-world therapeutic drug…

Machine Learning · Computer Science 2026-05-19 Yuan Xue , Daniel Kudenko , Megha Khosla

Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Amir Sadikov , Xinlei Pan , Hannah Choi , Lanya T. Cai , Pratik Mukherjee

Methodologies for multidimensionality reduction aim at discovering low-dimensional manifolds where data ranges. Principal Component Analysis (PCA) is very effective if data have linear structure. But fails in identifying a possible…

Numerical Analysis · Mathematics 2021-01-14 Alberto García-González , Antonio Huerta , Sergio Zlotnik , Pedro Díez

Adapters have become a widely adopted strategy for efficient fine-tuning of large pretrained models, particularly in resource-constrained settings. However, their performance under extreme data scarcity, common in medical imaging due to…

Computational Engineering, Finance, and Science · Computer Science 2026-02-24 Ziquan Zhu , Hanruo Zhu , Siyuan Lu , Xiang Li , Yanda Meng , Gaojie Jin , Lu Yin , Lijie Hu , Di Wang , Lu Liu , Tianjin Huang

Principal component analysis (PCA) is widely used for feature extraction and dimensionality reduction, with documented merits in diverse tasks involving high-dimensional data. Standard PCA copes with one dataset at a time, but it is…

Machine Learning · Computer Science 2019-01-30 Jia Chen , Gang Wang , Georgios B. Giannakis

Traditional breast cancer imaging methods using microwave Nearfield Radar Imaging (NRI) seek to recover the complex permittivity of the tissues at each voxel in the imaging region. This approach is suboptimal, in that it does not directly…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Richard Obermeier , Jose Angel Martinez-Lorenzo

Regularization for denoising in magnetic resonance imaging (MRI) is typically achieved using convex regularization functions. Recently, deep learning techniques have been shown to provide superior denoising performance. However, this comes…

Signal Processing · Electrical Eng. & Systems 2025-08-21 Akash Prabakar , Abhishek Shreekant Bhandiwad , Abijith Jagannath Kamath , Chandra Sekhar Seelamantula

Pansharpening techniques aim at fusing low-resolution multispectral (MS) images and high-resolution panchromatic (PAN) images to produce high-resolution MS images. Despite significant progress in the field, spectral and spatial distortions…

Computer Vision and Pattern Recognition · Computer Science 2019-03-15 Joan Duran , Antoni Buades
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