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Using multimodal Magnetic Resonance Imaging (MRI) is necessary for accurate brain tumor segmentation. The main problem is that not all types of MRIs are always available in clinical exams. Based on the fact that there is a strong…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

Domain shift poses a fundamental challenge in time series analysis, where models trained on source domain often fail dramatically when applied in target domain with different yet similar distributions. While current unsupervised domain…

Machine Learning · Computer Science 2025-08-07 Rongyao Cai , Ming Jin , Qingsong Wen , Kexin Zhang

Missing modalities pose a major issue in Alzheimer's Disease (AD) diagnosis, as many subjects lack full imaging data due to cost and clinical constraints. While multi-modal learning leverages complementary information, most existing methods…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Yanfei Li , Teng Yin , Wenyi Shang , Jingyu Liu , Xi Wang , Kaiyang Zhao

The detection of anomalous tissue regions (ATRs) within affected tissues is crucial in clinical diagnosis and pathological studies. Conventional automated ATR detection methods, primarily based on histology images alone, falter in cases…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Kaichen Xu , Qilong Wu , Yan Lu , Yinan Zheng , Wenlin Li , Xingjie Tang , Jun Wang , Xiaobo Sun

In recent years, traffic flow prediction has become a highlight in the field of intelligent transportation systems. However, due to the temporal variations and dynamic spatial correlations of traffic data, traffic prediction remains highly…

Artificial Intelligence · Computer Science 2025-06-04 Tianfan Jiang , Mei Wu , Wenchao Weng , Dewen Seng , Yiqian Lin

Anomaly detection for Magnetic Resonance Images (MRIs) can be solved with unsupervised methods by learning the distribution of healthy images and identifying anomalies as outliers. In presence of an additional dataset of unlabelled data…

Machine Learning · Computer Science 2020-07-27 Alexandra-Ioana Albu , Alina Enescu , Luigi Malagò

Disentangled representation learning offers useful properties such as dimension reduction and interpretability, which are essential to modern deep learning approaches. Although deep learning techniques have been widely applied to…

Machine Learning · Computer Science 2022-04-11 Sichen Zhao , Wei Shao , Jeffrey Chan , Flora D. Salim

Multivariate time-series data are frequently observed in critical care settings and are typically characterized by sparsity (missing information) and irregular time intervals. Existing approaches for learning representations in this domain…

Machine Learning · Computer Science 2022-02-17 Sindhu Tipirneni , Chandan K. Reddy

Gene expression profiles have been widely used to characterize patterns of cellular responses to diseases. As data becomes available, scalable learning toolkits become essential to processing large datasets using deep learning models to…

Machine Learning · Computer Science 2019-02-01 Ya Ju Fan , Jonathan E. Allen , Sam Ade Jacobs , Brian C. Van Essen

Real-world time series typically exhibit complex temporal variations, making the time series classification task notably challenging. Recent advancements have demonstrated the potential of multi-scale analysis approaches, which provide an…

Artificial Intelligence · Computer Science 2025-07-25 Zhipeng Liu , Peibo Duan , Binwu Wang , Xuan Tang , Qi Chu , Changsheng Zhang , Yongsheng Huang , Bin Zhang

While tumor dynamic modeling has been widely applied to support the development of oncology drugs, there remains a need to increase predictivity, enable personalized therapy, and improve decision-making. We propose the use of Tumor Dynamic…

Quantitative Methods · Quantitative Biology 2023-10-24 Mark Laurie , James Lu

Recent advancements in feature representation and dimension reduction have highlighted their crucial role in enhancing the efficacy of predictive modeling. This work introduces TemporalPaD, a novel end-to-end deep learning framework…

Machine Learning · Computer Science 2024-09-30 Xuechen Mu , Zhenyu Huang , Kewei Li , Haotian Zhang , Xiuli Wang , Yusi Fan , Kai Zhang , Fengfeng Zhou

Cardiac Magnetic Resonance (CMR) imaging is a critical tool for diagnosing and managing cardiovascular disease, yet its utility is often limited by the sparse acquisition of 2D short-axis slices, resulting in incomplete volumetric…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Niklas Bubeck , Suprosanna Shit , Chen Chen , Can Zhao , Pengfei Guo , Dong Yang , Georg Zitzlsberger , Daguang Xu , Bernhard Kainz , Daniel Rueckert , Jiazhen Pan

Deep learning models have made significant advances in histological prediction tasks in recent years. However, for adaptation in clinical practice, their lack of robustness to varying conditions such as staining, scanner, hospital, and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 David Jacob Drexlin , Jonas Dippel , Julius Hense , Niklas Prenißl , Grégoire Montavon , Frederick Klauschen , Klaus-Robert Müller

Although deep learning models in medical imaging often achieve excellent classification performance, they can rely on shortcut learning, exploiting spurious correlations or confounding factors that are not causally related to the target…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Sarah Müller , Philipp Berens

Real-world clinical data is inherently multimodal, providing complementary evidence that mirrors the practical necessity of jointly assessing multiple related outcomes. Although multi-task learning can improve efficiency by sharing…

Machine Learning · Computer Science 2026-05-06 He Lyu , Huolin Zeng , Junren Wang , Huazhen Yang , Linchao He , Yong Chen , Zhirui Li , Andreas Maier , Siming Bayer , Huan Song

We propose small-variance asymptotic approximations for the inference of tumor heterogeneity (TH) using next-generation sequencing data. Understanding TH is an important and open research problem in biology. The lack of appropriate…

Methodology · Statistics 2015-11-17 Yanxun Xu , Peter Mueller , Yuan Yuan , Kamalakar Gulukota , Yuan Ji

Incomplete multi-modal medical image segmentation faces critical challenges from modality imbalance, including imbalanced modality missing rates and heterogeneous modality contributions. Due to their reliance on idealized assumptions of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Libin Lan , Hongxing Li , Zunhui Xia , Yudong Zhang

Effective therapy decisions require models that predict the individual response to treatment. This is challenging since the progression of disease and response to treatment vary substantially across patients. Here, we propose to learn a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Ivana Janíčková , Yen Y. Tan , Thomas H. Helbich , Konstantin Miloserdov , Zsuzsanna Bago-Horvath , Ulrike Heber , Georg Langs

Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Julian Schön , Raghavendra Selvan , Lotte Nygård , Ivan Richter Vogelius , Jens Petersen
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