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We propose a framework for constructing combinatorial complexes (CCs) from fMRI time series data that captures both pairwise and higher-order neural interactions through information-theoretic measures, bridging topological deep learning and…

Neurons and Cognition · Quantitative Biology 2026-01-06 Valentina Sánchez , Çiçek Güven , Koen Haak , Theodore Papamarkou , Gonzalo Nápoles , Marie Šafář Postma

Cardiovascular disease (CVD) continues to be the major cause of death globally, calling for predictive models that not only handle diverse and high-dimensional biomedical signals but also maintain interpretability and privacy. We create a…

Machine Learning · Computer Science 2026-01-13 Rohit Kaushik , Eva Kaushik

Automated cardiac segmentation from magnetic resonance imaging datasets is an essential step in the timely diagnosis and management of cardiac pathologies. We propose to tackle the problem of automated left and right ventricle segmentation…

Computer Vision and Pattern Recognition · Computer Science 2017-04-28 Phi Vu Tran

Breast cancer exhibits intricate morphological and dynamical heterogeneity across cellular, tissue, and tumor scales, posing challenges to conventional modeling approaches that fail to capture its nonlinear, self-similar, or self-affine,…

Quantitative Methods · Quantitative Biology 2025-11-18 Abhijeet Das , Ramray Bhat , Mohit Kumar Jolly

Although the preservation of shape continuity and physiological anatomy is a natural assumption in the segmentation of medical images, it is often neglected by deep learning methods that mostly aim for the statistical modeling of input data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Yousef Yeganeh , Azade Farshad , Goktug Guevercin , Amr Abu-zer , Rui Xiao , Yongjian Tang , Ehsan Adeli , Nassir Navab

With the accumulation of big data of CME observations by coronagraphs, automatic detection and tracking of CMEs has proven to be crucial. The excellent performance of convolutional neural network in image classification, object detection…

Solar and Stellar Astrophysics · Physics 2019-09-25 Pengyu Wang , Yan Zhang , Li Feng , Hanqing Yuan , Yuan Gan , Shuting Li , Lei Lu , Beili Ying , Weiqun Gan , Hui Li

An accurate assessment of the cardiovascular system and prediction of cardiovascular diseases (CVDs) are crucial. Measured cardiac blood flow data provide insights about patient-specific hemodynamics, where many specialized techniques have…

Visual graphics, such as plots, charts, and figures, are widely used to communicate statistical conclusions. Extracting information directly from such visualizations is a key sub-problem for effective search through scientific corpora,…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Dale Decatur , Sanjay Krishnan

Statistical techniques are needed to analyse data structures with complex dependencies such that clinically useful information can be extracted. Individual-specific networks, which capture dependencies in complex biological systems, are…

Methodology · Statistics 2023-08-30 Mariella Gregorich , Sean L. Simpson , Georg Heinze

With the growing volume of CT examinations, there is an increasing demand for automated tools such as organ segmentation, abnormality detection, and report generation to support radiologists in managing their clinical workload. Multi-label…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Theo Di Piazza , Carole Lazarus , Olivier Nempont , Loic Boussel

Precise segmentation of retinal arteries and veins carries the diagnosis of systemic cardiovascular conditions. However, standard convolutional architectures often yield topologically disjointed segmentations, characterized by gaps and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Iftekhar Ahmed , Shakib Absar , Aftar Ahmad Sami , Shadman Sakib , Debojyoti Biswas , Seraj Al Mahmud Mostafa

Cerebral small vessel disease (CSVD) is a major vascular contributor to cognitive impairment in ageing, including dementias. Imaging remains the most promising method for in vivo studies of CSVD. To replace the subjective and laborious…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Jiyang Jiang , Dadong Wang , Yang Song , Perminder S. Sachdev , Wei Wen

The comorbidities of hypertension impose a heavy burden on patients and society. Early identification is necessary to prompt intervention, but it remains a challenging task. This study aims to address this challenge by combining joint graph…

Machine Learning · Computer Science 2025-06-13 Leming Zhou , Zuo Wang , Zhixuan Duan

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Whilst grading neurovascular abnormalities is critical for prompt surgical repair, no statistical markers are currently available for predicting the risk of adverse events, such as stroke, and the overall resilience of a network to vascular…

Quantitative Methods · Quantitative Biology 2019-10-30 Stefano Moriconi , Rafael Rehwald , Maria A. Zuluaga , H. Rolf Jäger , Parashkev Nachev , Sébastien Ourselin , M. Jorge Cardoso

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Cardiac disease evaluation depends on multiple diagnostic modalities: electrocardiogram (ECG) to diagnose abnormal heart rhythms, and imaging modalities such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and echocardiography…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Evariste Njomgue Fotso , Buntheng Ly , Hubert Cochet , Maxime Sermesant

The correlation matrix is a central representation of functional brain networks in neuroimaging. Traditional analyses often treat pairwise interactions independently in a Euclidean setting, overlooking the intrinsic geometry of correlation…

Machine Learning · Statistics 2025-04-10 Kisung You , Yelim Lee , Hae-Jeong Park

Cardiac Magnetic Resonance (CMR) imaging is widely used for heart model reconstruction and digital twin computational analysis because of its ability to visualize soft tissues and capture dynamic functions. However, CMR images have an…