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Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…

Cytology is a valuable tool for early detection of oral squamous cell carcinoma (OSCC). However, manual examination of cytology whole slide images (WSIs) is slow, subjective, and depends heavily on expert pathologists. To address this, we…

Image and Video Processing · Electrical Eng. & Systems 2025-11-18 Rupam Mukherjee , Rajkumar Daniel , Soujanya Hazra , Shirin Dasgupta , Subhamoy Mandal

The ThinPrep Cytologic Test (TCT) is the most widely used method for cervical cancer screening, and the sample quality directly impacts the accuracy of the diagnosis. Traditional manual evaluation methods rely on the observation of…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Lanlan Kang , Jian Wang , Jian QIn , Yiqin Liang , Yongjun He

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

Digital pathology has attracted significant attention in recent years. Analysis of Whole Slide Images (WSIs) is challenging because they are very large, i.e., of Giga-pixel resolution. Identifying Regions of Interest (ROIs) is the first…

Image and Video Processing · Electrical Eng. & Systems 2020-09-21 A Nugaliyadde , Kok Wai Wong , Jeremy Parry , Ferdous Sohel , Hamid Laga , Upeka V. Somaratne , Chris Yeomans , Orchid Foster

The increasing availability of large institutional and public histopathology image datasets is enabling the searching of these datasets for diagnosis, research, and education. Though these datasets typically have associated metadata such as…

Renal cell carcinoma (RCC) is the most common renal cancer in adults. The histopathologic classification of RCC is essential for diagnosis, prognosis, and management of patients. Reorganization and classification of complex histologic…

Image and Video Processing · Electrical Eng. & Systems 2020-11-02 Mengdan Zhu , Bing Ren , Ryland Richards , Matthew Suriawinata , Naofumi Tomita , Saeed Hassanpour

Transrectal biopsies under 2D ultrasound (US) control are the current clinical standard for prostate cancer diagnosis. The isoechogenic nature of prostate carcinoma makes it necessary to sample the gland systematically, resulting in a low…

Computer Vision and Pattern Recognition · Computer Science 2011-07-11 Michael Baumann , Pierre Mozer , Vincent Daanen , Jocelyne Troccaz

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Automated region of interest detection in histopathological image analysis is a challenging and important topic with tremendous potential impact on clinical practice. The deep-learning methods used in computational pathology may help us to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Yi Cui , Yao Li , Jayson R. Miedema , Sharon N. Edmiston , Sherif Farag , J. S. Marron , Nancy E. Thomas

Background and Purpose: Colorectal cancer is a common fatal malignancy, the fourth most common cancer in men, and the third most common cancer in women worldwide. Timely detection of cancer in its early stages is essential for treating the…

Purpose: This paper presents the preliminary results of a semi-automatic method for prostate segmentation of Magnetic Resonance Images (MRI) which aims to be incorporated in a navigation system for prostate brachytherapy. Methods: The…

Other Computer Science · Computer Science 2008-12-18 Sébastien Martin , Vincent Daanen , Jocelyne Troccaz

While microscopic analysis of histopathological slides is generally considered as the gold standard method for performing cancer diagnosis and grading, the current method for analysis is extremely time consuming and labour intensive as it…

Computer Vision and Pattern Recognition · Computer Science 2018-06-25 Rene Bidart , Alexander Wong

The emergence of multi-parametric magnetic resonance imaging (mpMRI) has had a profound impact on the diagnosis of prostate cancers (PCa), which is the most prevalent malignancy in males in the western world, enabling a better selection of…

Early diagnosis of prostate cancer significantly improves a patient's 5-year survival rate. Biopsy of small prostate cancers is improved with image-guided biopsy. MRI-ultrasound fusion-guided biopsy is sensitive to smaller tumors but is…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Muhammad Imran , Brianna Nguyen , Jake Pensa , Sara M. Falzarano , Anthony E. Sisk , Muxuan Liang , John Michael DiBianco , Li-Ming Su , Yuyin Zhou , Wayne G. Brisbane , Wei Shao

Recent advances in agentic artificial intelligence, i.e. systems capable of autonomous perception, reasoning, and tool use, offer new opportunities for digital pathology. In this pilot study, we evaluate whether two agentic multimodal AI…

Human-Computer Interaction · Computer Science 2026-01-21 Marc Aubreville , Taryn A. Donovan , Christof A. Bertram

Histopathology tissue samples are widely available in two states: paraffin-embedded unstained and non-paraffin-embedded stained whole slide RGB images (WSRI). Hematoxylin and eosin stain (H&E) is one of the principal stains in histology but…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Aman Rana , Gregory Yauney , Alarice Lowe , Pratik Shah

The search and retrieval of digital histopathology slides is an important task that has yet to be solved. In this case study, we investigate the clinical readiness of three state-of-the-art histopathology slide search engines, Yottixel,…

Detection and diagnosis of colon polyps are key to preventing colorectal cancer. Recent evidence suggests that AI-based computer-aided detection (CADe) and computer-aided diagnosis (CADx) systems can enhance endoscopists' performance and…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Carlo Biffi , Giulio Antonelli , Sebastian Bernhofer , Cesare Hassan , Daizen Hirata , Mineo Iwatate , Andreas Maieron , Pietro Salvagnini , Andrea Cherubini

Computational histopathology has made significant strides in the past few years, slowly getting closer to clinical adoption. One area of benefit would be the automatic generation of diagnostic reports from H\&E-stained whole slide images…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Masayuki Tsuneki , Fahdi Kanavati
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