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To design and construct hardware for general intelligence, we must consider principles of both neuroscience and very-large-scale integration. For large neural systems capable of general intelligence, the attributes of photonics for…

Emerging Technologies · Computer Science 2021-05-05 Jeffrey M. Shainline

Recent research has demonstrated the usefulness of neural networks as variational ansatz functions for quantum many-body states. However, high-dimensional sampling spaces and transient autocorrelations confront these approaches with a…

Quantum Physics · Physics 2021-11-29 Robert Klassert , Andreas Baumbach , Mihai A. Petrovici , Martin Gärttner

As processes continue to scale aggressively, the design of deep sub-micron, mixed-signal design is becoming more and more challenging. In this paper we present an analysis of scaling multi-core mixed-signal neuromorphic processors to…

Emerging Technologies · Computer Science 2019-08-21 Ning Qiao , Giacomo Inidveri

Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…

Neurons and Cognition · Quantitative Biology 2026-04-01 Breno C. Bispo , Stefania Sardellitti , Juliano B. Lima , Fernando A. N. Santos

Recent efforts have fostered significant progress towards deep learning in spiking networks, both theoretical and in silico. Here, we discuss several different approaches, including a tentative comparison of the results on BrainScaleS-2,…

Spiking Neural Networks (SNNs) offer high energy efficiency and event-driven computation, ideal for low-power edge AI. Their hardware implementation on FPGAs, however, faces challenges due to heavy computation, large memory use, and limited…

Hardware Architecture · Computer Science 2026-03-20 Mohammad Javad Sekonji , Ali Mahani , Maryam Mirsadeghi , Mahdi Taheri

Brain-computer interfaces (BCIs) are an advanced fusion of neuroscience and artificial intelligence, requiring stable and long-term decoding of neural signals. Spiking Neural Networks (SNNs), with their neuronal dynamics and spike-based…

Neural and Evolutionary Computing · Computer Science 2024-10-07 Yu Song , Liyuan Han , Bo Xu , Tielin Zhang

Tensor parallelism (TP) in large-scale LLM inference and training introduces frequent collective operations that dominate inter-GPU communication. While in-switch computing, exemplified by NVLink SHARP (NVLS), accelerates collective…

Hardware Architecture · Computer Science 2026-05-08 Chen Zhang , Qijun Zhang , Zhuoshan Zhou , Yijia Diao , Haibo Wang , Zhe Zhou , Zhipeng Tu , Zhiyao Li , Guangyu Sun , Zhuoran Song , Zhigang Ji , Jingwen Leng , Minyi Guo

The proliferation of deep learning applications has intensified the demand for electronic hardware with low energy consumption and fast computing speed. Neuromorphic photonics have emerged as a viable alternative to directly process…

Applied Physics · Physics 2025-06-24 Guangfeng You , Chao Qian , Hongsheng Chen

Unlike traditional PCIe-based FPGA accelerators, heterogeneous SoC-FPGA devices provide tighter integrations between software running on CPUs and hardware accelerators. Modern heterogeneous SoC-FPGA platforms support multiple I/O cache…

Hardware Architecture · Computer Science 2019-08-06 Seung Won Min , Sitao Huang , Mohamed El-Hadedy , Jinjun Xiong , Deming Chen , Wen-mei Hwu

We present a neuromorphic Analogue-to-Digital Converter (ADC), which uses integrate-and-fire (I&F) neurons as the encoders of the analogue signal, with modulated inhibitions to decohere the neuronal spikes trains. The architecture consists…

Neural and Evolutionary Computing · Computer Science 2015-09-04 Ying Xu , Chetan Singh Thakur , Tara Julia Hamilton , Jonathan Tapson , Runchun Wang , Andre van Schaik

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

Multi-channel electrophysiology systems for recording of neuronal activity face significant data throughput limitations, hampering real-time, data-informed experiments. These limitations impact both experimental neurobiology research and…

In this paper, we develop an in-memory analog computing (IMAC) architecture realizing both synaptic behavior and activation functions within non-volatile memory arrays. Spin-orbit torque magnetoresistive random-access memory (SOT-MRAM)…

Hardware Architecture · Computer Science 2021-09-15 Mohammed Elbtity , Abhishek Singh , Brendan Reidy , Xiaochen Guo , Ramtin Zand

Brain-computer interfaces (BCIs), transform neural signals in the brain into in-structions to control external devices. However, obtaining sufficient training data is difficult as well as limited. With the advent of advanced machine…

Neurons and Cognition · Quantitative Biology 2024-07-02 Shengjie Zheng , Wenyi Li , Lang Qian , Chenggang He , Xiaojian Li

The Artificial Neural Networks (ANNs) like CNN/DNN and LSTM are not biologically plausible and in spite of their initial success, they cannot attain the cognitive capabilities enabled by the dynamic hierarchical associative memory systems…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-05-03 Dimitrios Stathis , Chirag Sudarshan , Yu Yang , Matthias Jung , Syed Asad Mohamad Hasan Jafri , Christian Weis , Ahmed Hemani , Anders Lansner , Norbert Wehn

Remarkable achievements have been attained by deep neural networks in various applications. However, the increasing depth and width of such models also lead to explosive growth in both storage and computation, which has restricted the…

Machine Learning · Computer Science 2019-06-11 Linfeng Zhang , Zhanhong Tan , Jiebo Song , Jingwei Chen , Chenglong Bao , Kaisheng Ma

Manycore System-on-Chip include an increasing amount of processing elements and have become an important research topic for improvements of both hardware and software. While research can be conducted using system simulators, prototyping…

Hardware Architecture · Computer Science 2013-04-19 Stefan Wallentowitz , Philipp Wagner , Michael Tempelmeier , Thomas Wild , Andreas Herkersdorf

Biological systems use neural circuits to integrate input information and produce outputs. Synaptic convergence, where multiple neurons converge their inputs onto a single downstream neuron, is common in natural neural circuits. However,…

Mesoscale and Nanoscale Physics · Physics 2026-02-04 Wendy Otieno , Alex Gabbitas , Debi Pattnaik , Pavel Borisov , Sergey Savel'ev , Alexander G. Balanov

Next-generation mixed-criticality Systems-on-chip (SoCs) for robotics, automotive, and space must execute mixed-criticality AI-enhanced sensor processing and control workloads, ensuring reliable and time-predictable execution of critical…