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Recent advances in general medical AI have made significant strides, but existing models often lack the reasoning capabilities needed for complex medical decision-making. This paper presents GMAI-VL-R1, a multimodal medical reasoning model…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Yanzhou Su , Tianbin Li , Jiyao Liu , Chenglong Ma , Junzhi Ning , Cheng Tang , Sibo Ju , Jin Ye , Pengcheng Chen , Ming Hu , Shixiang Tang , Lihao Liu , Bin Fu , Wenqi Shao , Xiaowei Hu , Xiangwen Liao , Yuanfeng Ji , Junjun He

Colonoscopic polyp diagnosis is pivotal for early colorectal cancer detection, yet traditional automated reporting suffers from inconsistencies and hallucinations due to the scarcity of high-quality multimodal medical data. To bridge this…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Tianyu Zhou , Junyi Tang , Zehui Li , Dahong Qian , Suncheng Xiang

Multimodal Large Language Models (MLLMs) strive to achieve a profound, human-like understanding of and interaction with the physical world, but often exhibit a shallow and incoherent integration when acquiring information (Perception) and…

Recent advancements in reasoning-enhanced large language models (LLMs), such as DeepSeek-R1 and OpenAI-o3, have demonstrated significant progress. However, their application in professional medical contexts remains underexplored,…

Computation and Language · Computer Science 2025-03-11 Pengcheng Qiu , Chaoyi Wu , Shuyu Liu , Weike Zhao , Zhuoxia Chen , Hongfei Gu , Chuanjin Peng , Ya Zhang , Yanfeng Wang , Weidi Xie

Visual spatial intelligence is critical for medical image interpretation, yet remains largely unexplored in Multimodal Large Language Models (MLLMs) for 3D imaging. This gap persists due to a systemic lack of datasets featuring structured…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Quoc-Huy Trinh , Xi Ding , Yang Liu , Zhenyue Qin , Xingjian Li , Gorkem Durak , Halil Ertugrul Aktas , Elif Keles , Ulas Bagci , Min Xu

Deep reasoning is fundamental for solving complex tasks, especially in vision-centric scenarios that demand sequential, multimodal understanding. However, existing benchmarks typically evaluate agents with fully synthetic, single-turn…

Reasoning is a critical frontier for advancing medical image analysis, where transparency and trustworthiness play a central role in both clinician trust and regulatory approval. Although Medical Visual Language Models (VLMs) show promise…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Jiazhen Pan , Che Liu , Junde Wu , Fenglin Liu , Jiayuan Zhu , Hongwei Bran Li , Chen Chen , Cheng Ouyang , Daniel Rueckert

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

We introduce MediX-R1, an open-ended Reinforcement Learning (RL) framework for medical multimodal large language models (MLLMs) that enables clinically grounded, free-form answers beyond multiple-choice formats. MediX-R1 fine-tunes a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Sahal Shaji Mullappilly , Mohammed Irfan Kurpath , Omair Mohamed , Mohamed Zidan , Fahad Khan , Salman Khan , Rao Anwer , Hisham Cholakkal

Logical reasoning is a fundamental aspect of human intelligence and an essential capability for multimodal large language models (MLLMs). Despite the significant advancement in multimodal reasoning, existing benchmarks fail to…

Artificial Intelligence · Computer Science 2025-05-28 Jiakang Yuan , Tianshuo Peng , Yilei Jiang , Yiting Lu , Renrui Zhang , Kaituo Feng , Chaoyou Fu , Tao Chen , Lei Bai , Bo Zhang , Xiangyu Yue

Brain imaging analysis is crucial for diagnosing and treating brain disorders, and multimodal large language models (MLLMs) are increasingly supporting it. However, current brain imaging visual question-answering (VQA) benchmarks either…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Zhihao Peng , Cheng Wang , Shengyuan Liu , Zhiying Liang , Zanting Ye , Minjie Ju , PeterYM Woo , Yixuan Yuan

Large language models have demonstrated substantial advancements in reasoning capabilities. However, current Vision-Language Models (VLMs) often struggle to perform systematic and structured reasoning, especially when handling complex…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Guowei Xu , Peng Jin , Ziang Wu , Hao Li , Yibing Song , Lichao Sun , Li Yuan

Faithful reasoning in medical vision-language models (VLMs) requires not only accurate predictions but also transparent alignment between textual rationales and visual evidence. While Chain-of-Thought (CoT) prompting has shown promise in…

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Multimodal reasoning, which integrates language and visual cues into problem solving and decision making, is a fundamental aspect of human intelligence and a crucial step toward artificial general intelligence. However, the evaluation of…

Multimodal large language models (MLLMs) have emerged as a promising paradigm for dental image analysis. However, their ability to capture the multi-level cognitive processes required for radiographic analysis remains unclear. Here, we…

Computation and Language · Computer Science 2026-05-11 Rongyang Wang , Shuang Zhou , Jiashuo Wang , Wenya Xie , Xiaoxia Che

While large language models show promise in medical applications, achieving expert-level clinical reasoning remains challenging due to the need for both accurate answers and transparent reasoning processes. To address this challenge, we…

Machine Learning · Computer Science 2025-09-22 Chi Liu , Derek Li , Yan Shu , Robin Chen , Derek Duan , Teng Fang , Bryan Dai

Multimodal Large Language Models (MLLMs) show promising results for embodied agents in operating meaningfully in complex, human-centered environments. Yet, evaluating their capacity for nuanced, human-like reasoning and decision-making…

Computation and Language · Computer Science 2025-09-30 Zhe Hu , Yixiao Ren , Guanzhong Liu , Jing Li , Yu Yin

Multimodal Large Language Models (MLLMs) have demonstrated impressive capabilities in understanding common visual elements, largely due to their large-scale datasets and advanced training strategies. However, their effectiveness in medical…

Multimodal large language models (MLLMs) demonstrate significant potential in the field of medical diagnosis. However, they face critical challenges in specialized domains such as ophthalmology, particularly the fragmentation of annotation…

Artificial Intelligence · Computer Science 2025-07-24 Xinyao Liu , Diping Song
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