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A deeper understanding of the influence of common cardiovascular diseases like stenosis, aneurysm or atherosclerosis on the circulatory mechanism is required, to establish new methods for early diagnosis. Different types of simulators were…

Arterial aneurysm (Fig.1) is a bulb-shape local expansion of human arteries, the rupture of which is a leading cause of morbidity and mortality in US. Therefore, the prediction of arterial aneurysm rupture is of great significance for…

Quantitative Methods · Quantitative Biology 2025-10-08 Jiacheng Wu

Accurate and rapid estimation of hemodynamic metrics, such as pressure and wall shear stress (WSS), is important for assessing the severity of Coronary Artery Disease (CAD). Existing approaches, including invasive Fractional Flow Reserve…

Computational Engineering, Finance, and Science · Computer Science 2026-05-28 Reza Akbarian Bafghi , Sukirt Thakur , Maziar Raissi

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

The accurate quantification of blood flow in aortoiliac arteries is challenging but clinically relevant because local flow patterns can influence atherosclerotic disease. To investigate the feasibility and clinical application of…

This study employs extensive three-dimensional direct numerical simulations (DNS) to investigate the influence of blood non-Newtonian behaviors on the hemodynamics around a bileaflet mechanical heart valve under both steady inflow and…

Fluid Dynamics · Physics 2024-05-01 A. Chauhan , C. Sasmal

Fluid-structure interaction (FSI) modeling, a technique widely used to enhance imaging modalities for adult and pediatric heart diseases, has been underutilized in the context of fetal circulation because of limited data on flow conditions…

Medical Physics · Physics 2024-10-29 Zhenglun Alan Wei , Guihong Chen , Biao Si , Liqun Sun , Mike Seed , Shuping Ge

Active nematic fluids confined in narrow channels generate spontaneous flows when the activity is sufficiently intense. Recently, it was shown that if the molecular anchoring at the channel walls is conflicting flows are initiated even in…

Soft Condensed Matter · Physics 2021-11-02 C. Rorai , F. Toschi , I. Pagonabarraga

The two most important aneurysm types are cerebral aneurysms (CA) and abdominal aortic aneurysms (AAA), accounting together for over 80\% of all fatal aneurysm incidences. To minimise aneurysm related deaths, clinicians require various…

Accurate, patient-specific vascular geometry is pivotal for diagnosis, planning, and device design, yet existing statistical shape modeling (SSM) pipelines rely on linear priors and topology-specific preprocessing that limit realism,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Pan Du , Mingqi Xu , Xiaozhi Zhu , Jian-xun Wang

This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…

Abdominal aortic aneurysm (AAA) is a vascular disease in which a section of the aorta enlarges, weakening its walls and potentially rupturing the vessel. Abdominal ultrasound has been utilized for diagnostics, but due to its limited image…

Image and Video Processing · Electrical Eng. & Systems 2022-08-12 Yordanka Velikova , Walter Simson , Mehrdad Salehi , Mohammad Farid Azampour , Philipp Paprottka , Nassir Navab

In Nature, liquids often circulate in channels textured with leaflets, cilia or porous walls that deform with the flow. These soft structures are optimized to passively control flows and inspire the design of novel microfluidic and soft…

Soft Condensed Matter · Physics 2020-08-19 Martin Brandenbourger , Adrien Dangremont , Rudolf Sprik , Corentin Coulais

In this paper a method is introduced, to visualize bifurcated stent grafts in CT-Data. The aim is to improve therapy planning for minimal invasive treatment of abdominal aortic aneurysms (AAA). Due to precise measurement of the abdominal…

Graphics · Computer Science 2016-02-09 Jan Egger , Stefan Großkopf , Bernd Freisleben

Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However,…

Computational Engineering, Finance, and Science · Computer Science 2024-07-02 Caglar Ozturk , Daniel H. Pak , Luca Rosalia , Debkalpa Goswami , Mary E. Robakowski , Raymond McKay , Christopher T. Nguyen , James S. Duncan , Ellen T. Roche

Patients that undergo the arterial switch operation (ASO) to repair transposition of great arteries (TGA) can develop abnormal pulmonary trunk morphology with significant long-term complications. In this study, cardiovascular magnetic…

Medical Physics · Physics 2018-09-18 Francesco Capuano , Yue-Hin Loke , Ileen Cronin , Laura J. Olivieri , Elias Balaras

Three intra-aortic blood pumps were evaluated and compared using CFD simulations. The aim of this study is to evaluate the hemodynamic performance and calculate the hemolytic potential of the pumps. The flow fields generated by the pumps…

Medical Physics · Physics 2026-03-31 Osman Aycan , Yeojin Park , Lyes Kadem

The ability to map left ventricle (LV) myocardial motion using computed tomography angiography (CTA) is essential to diagnosing cardiovascular conditions and guiding interventional procedures. Due to their inherent locality, conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Shahar Zuler , Shai Tejman-Yarden , Dan Raviv

In this paper, we explored the use of deep learning for the prediction of aortic flow metrics obtained using 4D flow MRI using wearable seismocardiography (SCG) devices. 4D flow MRI provides a comprehensive assessment of cardiovascular…

It has been shown that geometrical, structural properties vary along the length of the aortic arch. There is a scarcity of studies focus on the variation in the vessel wall thickness of aortic arch. The central premise of this study is that…

Tissues and Organs · Quantitative Biology 2018-06-21 Xiaochang Leng , Xingjian Liu , Will Toress , Tarek Shazly