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Cell detection in microscopy images is important to study how cells move and interact with their environment. Most recent deep learning-based methods for cell detection use convolutional neural networks (CNNs). However, inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Royden Wagner , Karl Rohr

Cell tracking is a ubiquitous image analysis task in live-cell microscopy. Unlike multiple object tracking (MOT) for natural images, cell tracking typically involves hundreds of similar-looking objects that can divide in each frame, making…

Computer Vision and Pattern Recognition · Computer Science 2024-07-25 Benjamin Gallusser , Martin Weigert

Molecular and genomic properties are critical in selecting cancer treatments to target individual tumors, particularly for immunotherapy. However, the methods to assess such properties are expensive, time-consuming, and often not routinely…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Heather D. Couture

Large-scale cell microscopy screens are used in drug discovery and molecular biology research to study the effects of millions of chemical and genetic perturbations on cells. To use these images in downstream analysis, we need models that…

Spatial transcriptomics methods capture cellular measurements such as gene expression and cell types at specific locations in a cell, helping provide a localized picture of tissue health. Traditional visualization techniques superimpose the…

Quantitative Methods · Quantitative Biology 2024-10-16 Siyuan Zhao , G. Elisabeta Marai

Histopathology, the microscopic study of diseased tissue, is increasingly digitized, enabling improved visualization and streamlined workflows. An important task in histopathology is the segmentation of cells and glands, essential for…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Philipp Endres , Valentin Koch , Julia A. Schnabel , Carsten Marr

Clustering is a technique for the analysis of datasets obtained by empirical studies in several disciplines with a major application for biomedical research. Essentially, clustering algorithms are executed by machines aiming at finding…

Quantitative Methods · Quantitative Biology 2024-09-30 Diego Ulisse Pizzagalli , Santiago Fernandez Gonzalez , Rolf Krause

This extended abstract presents a visualization system, which is designed for domain scientists to visually understand their deep learning model of extracting multiple attributes in x-ray scattering images. The system focuses on studying…

Machine Learning · Computer Science 2019-10-11 Xinyi Huang , Suphanut Jamonnak , Ye Zhao , Boyu Wang , Minh Hoai , Kevin Yager , Wei Xu

Identification of disease subtypes and corresponding biomarkers can substantially improve clinical diagnosis and treatment selection. Discovering these subtypes in noisy, high dimensional biomedical data is often impossible for humans and…

Quantitative Methods · Quantitative Biology 2020-05-18 Marc-Andre Schulz , Matt Chapman-Rounds , Manisha Verma , Danilo Bzdok , Konstantinos Georgatzis

Recently, biclustering is one of the hot topics in bioinformatics and takes the attention of authors from several different disciplines. Hence, many different methodologies from a variety of disciplines are proposed as a solution to the…

Human-Computer Interaction · Computer Science 2021-11-26 Melih Sozdinler

Imaging assays of cellular function, especially those using fluorescent stains, are ubiquitous in the biological and medical sciences. Despite advances in computer vision, such images are often analyzed using only manual or rudimentary…

Computer Vision and Pattern Recognition · Computer Science 2017-06-06 Lena R. Bartell , Lawrence J. Bonassar , Itai Cohen

Marine microalgae are widespread in the ocean and play a crucial role in the ecosystem. Automatic identification and location of marine microalgae in microscopy images would help establish marine ecological environment monitoring and water…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Shizheng Zhou , Juntao Jiang , Xiaohan Hong , Yan Hong , Pengcheng Fu

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Nowadays, the amount of heterogeneous biomedical data is increasing more and more thanks to novel sensing techniques and high-throughput technologies. In reference to biomedical image analysis, the advances in image acquisition modalities…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Leonardo Rundo

Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Shahin Mohammadi , Neta Zuckerman , Andrea Goldsmith , Ananth Grama

In an effort to catalog insect biodiversity, we propose a new large dataset of hand-labelled insect images, the BIOSCAN-Insect Dataset. Each record is taxonomically classified by an expert, and also has associated genetic information…

In recent years, deep learning models have been extensively applied to biological data across various modalities. Discriminative deep learning models have excelled at classifying images into categories (e.g., healthy versus diseased,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Anis Bourou , Saranga Kingkor Mahanta , Thomas Boyer , Valérie Mezger , Auguste Genovesio

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

Quantitative Methods · Quantitative Biology 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Computer vision is driven by the many datasets available for training or evaluating novel methods. However, each dataset has a different set of class labels, visual definition of classes, images following a specific distribution, annotation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-10 Jasper Uijlings , Thomas Mensink , Vittorio Ferrari

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

Quantitative Methods · Quantitative Biology 2022-08-12 Richard Tjörnhammar