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Wastewater surveillance has emerged as a critical public health tool, enabling early detection of infectious disease outbreaks and providing timely, population-level insights into community health trends. However, variability in sample…

Anomaly detection in multivariate time series is a critical task across a wide range of real-world applications, where abnormal behaviour is rare, labels are unavailable, and the cost of a miss is high. The central challenge is learning a…

Machine Learning · Computer Science 2026-05-25 Alberto D. Cencillo , Leonardo Concepción , Isaac Triguero , Julián Luengo

We propose an algorithm, guided variational autoencoder (Guided-VAE), that is able to learn a controllable generative model by performing latent representation disentanglement learning. The learning objective is achieved by providing…

Computer Vision and Pattern Recognition · Computer Science 2020-04-06 Zheng Ding , Yifan Xu , Weijian Xu , Gaurav Parmar , Yang Yang , Max Welling , Zhuowen Tu

Pan-cancer classification using transcriptomic (RNA-Seq) data can inform tumor subtyping and therapy selection, but is challenging due to extremely high dimensionality and limited sample sizes. In this study, we propose a novel deep…

Genomics · Quantitative Biology 2025-08-06 Vinil Polepalli

Variational autoencoders (VAEs) are one of the powerful likelihood-based generative models with applications in many domains. However, they struggle to generate high-quality images, especially when samples are obtained from the prior…

Machine Learning · Computer Science 2021-11-05 Jyoti Aneja , Alexander Schwing , Jan Kautz , Arash Vahdat

Estimation of uncertainty in deep learning models is of vital importance, especially in medical imaging, where reliance on inference without taking into account uncertainty could lead to misdiagnosis. Recently, the probabilistic Variational…

Machine Learning · Computer Science 2020-10-20 Haleh Akrami , Anand A. Joshi , Sergul Aydore , Richard M. Leahy

Vector quantization (VQ) based ANN indexes, such as Inverted File System (IVF) and Product Quantization (PQ), have been widely applied to embedding based document retrieval thanks to the competitive time and memory efficiency. Originally,…

Information Retrieval · Computer Science 2022-04-29 Shitao Xiao , Zheng Liu , Weihao Han , Jianjin Zhang , Defu Lian , Yeyun Gong , Qi Chen , Fan Yang , Hao Sun , Yingxia Shao , Denvy Deng , Qi Zhang , Xing Xie

Repeated waves of emerging variants during the SARS-CoV-2 pandemics have highlighted the urge of collecting longitudinal genomic data and developing statistical methods based on time series analyses for detecting new threatening lineages…

Quantitative Methods · Quantitative Biology 2025-01-14 Alexandra Lefebvre , Vincent Maréchal , Arnaud Gloaguen , Obépine Consortium , Amaury Lambert , Yvon Maday

Contrastive learning has proven to be highly efficient and adaptable in shaping representation spaces across diverse modalities by pulling similar samples together and pushing dissimilar ones apart. However, two key limitations persist: (1)…

Machine Learning · Computer Science 2025-12-08 Ziwen Wang , Jiajun Fan , Thao Nguyen , Heng Ji , Ge Liu

Due to their unsupervised training and uncertainty estimation, deep Variational Autoencoders (VAEs) have become powerful tools for reconstruction-based Time Series Anomaly Detection (TSAD). Existing VAE-based TSAD methods, either…

Machine Learning · Computer Science 2024-01-09 Zhangkai Wu , Longbing Cao , Qi Zhang , Junxian Zhou , Hui Chen

Deep generative models have demonstrated their effectiveness in learning latent representation and modeling complex dependencies of time series. In this paper, we present a Smoothness-Inducing Sequential Variational Auto-Encoder (SISVAE)…

Machine Learning · Computer Science 2021-02-03 Longyuan Li , Junchi Yan , Haiyang Wang , Yaohui Jin

Many real-world monitoring and surveillance applications require non-trivial anomaly detection to be run in the streaming model. We consider an incremental-learning approach, wherein a deep-autoencoding (DAE) model of what is normal is…

Computer Vision and Pattern Recognition · Computer Science 2019-12-11 Albert Akhriev , Jakub Marecek

We propose a multi-layer variational autoencoder method, we call HR-VQVAE, that learns hierarchical discrete representations of the data. By utilizing a novel objective function, each layer in HR-VQVAE learns a discrete representation of…

Computer Vision and Pattern Recognition · Computer Science 2022-08-10 Mohammad Adiban , Kalin Stefanov , Sabato Marco Siniscalchi , Giampiero Salvi

Waste classification is crucial for improving processing efficiency and reducing environmental pollution. Supervised deep learning methods are commonly used for automated waste classification, but they rely heavily on large labeled…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Kui Huang , Mengke Song , Shuo Ba , Ling An , Huajie Liang , Huanxi Deng , Yang Liu , Zhenyu Zhang , Chichun Zhou

In the contrastive analysis (CA) setting, machine learning practitioners are specifically interested in discovering patterns that are enriched in a target dataset as compared to a background dataset generated from sources of variation…

Machine Learning · Computer Science 2022-02-23 Ethan Weinberger , Nicasia Beebe-Wang , Su-In Lee

In this paper, we explore vector quantization for acoustic unit discovery. Leveraging unlabelled data, we aim to learn discrete representations of speech that separate phonetic content from speaker-specific details. We propose two neural…

Audio and Speech Processing · Electrical Eng. & Systems 2020-08-20 Benjamin van Niekerk , Leanne Nortje , Herman Kamper

Learning disentangled representations without supervision or inductive biases, often leads to non-interpretable or undesirable representations. On the other hand, strict supervision requires detailed knowledge of the true generative…

Machine Learning · Computer Science 2020-08-25 Vasilis Margonis , Athanasios Davvetas , Iraklis A. Klampanos

Vector Quantized Variational Autoencoders (VQ-VAEs) are fundamental to modern generative modeling, yet they often suffer from training instability and "codebook collapse" due to the inherent coupling of representation learning and discrete…

Machine Learning · Computer Science 2026-02-20 Linwei Zhai , Han Ding , Mingzhi Lin , Cui Zhao , Fei Wang , Ge Wang , Wang Zhi , Wei Xi

A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…

Computer Vision and Pattern Recognition · Computer Science 2020-11-02 Krishna Chaitanya , Ertunc Erdil , Neerav Karani , Ender Konukoglu

Vector quantised variational autoencoders (VQ-VAE) are characterised by three main components: 1) encoding visual data, 2) assigning $k$ different vectors in the so-called embedding space, and 3) decoding the learnt features. While images…

Computer Vision and Pattern Recognition · Computer Science 2020-10-01 Arash Akbarinia , Raquel Gil-Rodríguez , Alban Flachot , Matteo Toscani