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Variational autoencoders are powerful algorithms for identifying dominant latent structure in a single dataset. In many applications, however, we are interested in modeling latent structure and variation that are enriched in a target…

Machine Learning · Computer Science 2019-02-14 Abubakar Abid , James Zou

In this paper we demonstrate methods for reliable and efficient training of discrete representation using Vector-Quantized Variational Auto-Encoder models (VQ-VAEs). Discrete latent variable models have been shown to learn nontrivial…

The vector quantization is a widely used method to map continuous representation to discrete space and has important application in tokenization for generative mode, bottlenecking information and many other tasks in machine learning. Vector…

Machine Learning · Computer Science 2024-10-15 Mingyuan Yan , Jiawei Wu , Rushi Shah , Dianbo Liu

Learning deep discrete latent presentations offers a promise of better symbolic and summarized abstractions that are more useful to subsequent downstream tasks. Inspired by the seminal Vector Quantized Variational Auto-Encoder (VQ-VAE),…

Machine Learning · Computer Science 2023-06-21 Tung-Long Vuong , Trung Le , He Zhao , Chuanxia Zheng , Mehrtash Harandi , Jianfei Cai , Dinh Phung

The de novo design of drug molecules is recognized as a time-consuming and costly process, and computational approaches have been applied in each stage of the drug discovery pipeline. Variational autoencoder is one of the computer-aided…

Quantum Physics · Physics 2021-12-24 Junde Li , Swaroop Ghosh

Vector quantization (VQ) is a technique to deterministically learn features with discrete codebook representations. It is commonly performed with a variational autoencoding model, VQ-VAE, which can be further extended to hierarchical…

Learning interpretable representations of data remains a central challenge in deep learning. When training a deep generative model, the observed data are often associated with certain categorical labels, and, in parallel with learning to…

Machine Learning · Computer Science 2019-10-01 Yifan Xue , Michael Ding , Xinghua Lu

In light of the continuous transmission and evolution of SARS-CoV-2 coupled with a significant decline in clinical testing, there is a pressing need for scalable, cost-effective, long-term, passive surveillance tools to effectively monitor…

Semi-supervised learning is sought for leveraging the unlabelled data when labelled data is difficult or expensive to acquire. Deep generative models (e.g., Variational Autoencoder (VAE)) and semisupervised Generative Adversarial Networks…

Machine Learning · Computer Science 2019-05-09 Xiang Zhang , Lina Yao , Feng Yuan

Uncovering emergent concepts across transformer layers remains a significant challenge because the residual stream linearly mixes and duplicates information, obscuring how features evolve within large language models. Current research…

Machine Learning · Computer Science 2025-07-18 Ankur Garg , Xuemin Yu , Hassan Sajjad , Samira Ebrahimi Kahou

Motivation: PCR is more economical and quicker than Next Generation Sequencing for detecting target organisms, with primer design being a critical step. In epidemiology with rapidly mutating viruses, designing effective primers is…

Genomics · Quantitative Biology 2025-12-18 Hanyu Wang , Emmanuel K. Tsinda , Anthony J. Dunn , Francis Chikweto , Alain B. Zemkoho

We present a novel application of Vector quantised variational autoencoders (VQ-VAEs) to deep 1.28 GHz radio continuum images taken from the MeerKAT Galaxy Cluster Legacy Survey (MGCLS).VQ-VAEs are deep learning models widely used in modern…

Instrumentation and Methods for Astrophysics · Physics 2026-01-21 Fernando L. Ventura , Kshitij Thorat , Anna Bosman , Roger Deane , Christopher Cleghorn

High-dimensional clinical data have become invaluable resources for genetic studies, due to their accessibility in biobank-scale datasets and the development of high performance modeling techniques especially using deep learning. Recent…

Machine Learning · Computer Science 2023-07-19 Taedong Yun

Deep neural networks with discrete latent variables offer the promise of better symbolic reasoning, and learning abstractions that are more useful to new tasks. There has been a surge in interest in discrete latent variable models, however,…

Machine Learning · Computer Science 2018-07-23 Aurko Roy , Ashish Vaswani , Arvind Neelakantan , Niki Parmar

Defining and separating cancer subtypes is essential for facilitating personalized therapy modality and prognosis of patients. The definition of subtypes has been constantly recalibrated as a result of our deepened understanding. During…

Machine Learning · Computer Science 2022-07-21 Zheng Chen , Ziwei Yang , Lingwei Zhu , Guang Shi , Kun Yue , Takashi Matsubara , Shigehiko Kanaya , MD Altaf-Ul-Amin

Unsupervised visual defect detection is critical in industrial applications, requiring a representation space that captures normal data features while detecting deviations. Achieving a balance between expressiveness and compactness is…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Qisen Cheng , Shuhui Qu , Janghwan Lee

Variational autoencoders (VAEs) are fundamental for generative modeling and image reconstruction, yet their performance often struggles to maintain high fidelity in reconstructions. This study introduces a hybrid model, quantum variational…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Farina Riaz , Fakhar Zaman , Hajime Suzuki , Sharif Abuadbba , David Nguyen

Automatic speaker verification (ASV) systems are highly vulnerable to presentation attacks, also called spoofing attacks. Replay is among the simplest attacks to mount - yet difficult to detect reliably. The generalization failure of…

Audio and Speech Processing · Electrical Eng. & Systems 2020-03-24 Bhusan Chettri , Tomi Kinnunen , Emmanouil Benetos

Given the complex geometry of white matter streamlines, Autoencoders have been proposed as a dimension-reduction tool to simplify the analysis streamlines in a low-dimensional latent spaces. However, despite these recent successes, the…

Machine Learning · Statistics 2023-11-21 Andrew Lizarraga , Brandon Taraku , Edouardo Honig , Ying Nian Wu , Shantanu H. Joshi

Contrastive Analysis VAE (CA-VAEs) is a family of Variational auto-encoders (VAEs) that aims at separating the common factors of variation between a background dataset (BG) (i.e., healthy subjects) and a target dataset (TG) (i.e., patients)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Robin Louiset , Edouard Duchesnay , Antoine Grigis , Benoit Dufumier , Pietro Gori
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