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AI agent frameworks connecting large language model (LLM) reasoning to host execution surfaces -- shell, filesystem, containers, and messaging -- introduce security challenges structurally distinct from conventional software. We present a…

Cryptography and Security · Computer Science 2026-05-15 Surada Suwansathit , Yuxuan Zhang , Guofei Gu

AI models are already deployed in societies affected by armed conflict, and journalists, humanitarian workers, governments and ordinary citizens rely on them for information or for their work processes. No established practice exists for…

Artificial Intelligence · Computer Science 2026-05-22 Andrii Kryshtal

AI agents powered by large language models (LLMs) have shown strong capabilities in problem solving. Through combining many intelligent agents, multi-agent collaboration has emerged as a promising approach to tackle complex, multi-faceted…

Computation and Language · Computer Science 2024-12-10 Raphael Shu , Nilaksh Das , Michelle Yuan , Monica Sunkara , Yi Zhang

Large language models (LLMs) show promise in clinical decision support yet risk acquiescing to patient pressure for inappropriate care. We introduce SycoEval-EM, a multi-agent simulation framework evaluating LLM robustness through…

Artificial Intelligence · Computer Science 2026-03-05 Dongshen Peng , Yi Wang , Austin Schoeffler , Carl Preiksaitis , Christian Rose

The construction industry is characterized by both high physical and psychological risks, yet supports of mental health remain limited. While advancements in artificial intelligence (AI), particularly large language models (LLMs), offer…

Human-Computer Interaction · Computer Science 2025-06-10 Fan Yang , Yuan Tian , Jiansong Zhang

Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

AI agents powered by large language models (LLMs) are being deployed at scale, yet we lack a systematic understanding of how the choice of backbone LLM affects agent security. The non-deterministic sequential nature of AI agents complicates…

Cryptography and Security · Computer Science 2026-02-25 Julia Bazinska , Max Mathys , Francesco Casucci , Mateo Rojas-Carulla , Xander Davies , Alexandra Souly , Niklas Pfister

As Large Language Models (LLMs) grow increasingly powerful, multi-agent systems are becoming more prevalent in modern AI applications. Most safety research, however, has focused on vulnerabilities in single-agent LLMs. These include prompt…

Multiagent Systems · Computer Science 2024-10-11 Donghyun Lee , Mo Tiwari

If two experts disagree on a test, we may conclude both cannot be 100 per cent correct. But if they completely agree, no possible evaluation can be excluded. This asymmetry in the utility of agreements versus disagreements is explored here…

Artificial Intelligence · Computer Science 2025-10-02 Andrés Corrada-Emmanuel

Large language models are prone to misuse and vulnerable to security threats, raising significant safety and security concerns. The European Union's Artificial Intelligence Act seeks to enforce AI robustness in certain contexts, but faces…

Cryptography and Security · Computer Science 2024-10-10 Tomas Bueno Momcilovic , Beat Buesser , Giulio Zizzo , Mark Purcell , Dian Balta

LLM-powered Multi-Agent Systems (LLM-MAS) unlock new potentials in distributed reasoning, collaboration, and task generalization but also introduce additional risks due to unguaranteed agreement, cascading uncertainty, and adversarial…

Multiagent Systems · Computer Science 2025-10-22 Jinwei Hu , Yi Dong , Shuang Ao , Zhuoyun Li , Boxuan Wang , Lokesh Singh , Guangliang Cheng , Sarvapali D. Ramchurn , Xiaowei Huang

As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Human-Computer Interaction · Computer Science 2026-05-19 Zeshan Hussain , Barbara D. Lam , Fernando A. Acosta-Perez , Irbaz Bin Riaz , Maia Jacobs , Andrew J. Yee , David Sontag

Large Language Models (LLMs) have shown remarkable promise in communicating with humans. Their potential use as artificial partners with humans in sociological experiments involving conversation is an exciting prospect. But how viable is…

Artificial Intelligence · Computer Science 2025-02-04 James Flamino , Mohammed Shahid Modi , Boleslaw K. Szymanski , Brendan Cross , Colton Mikolajczyk

The field of artificial intelligence (AI) agents is evolving rapidly, driven by the capabilities of Large Language Models (LLMs) to autonomously perform and refine tasks with human-like efficiency and adaptability. In this context,…

Statistical Finance · Quantitative Finance 2025-08-18 Tianjiao Zhao , Jingrao Lyu , Stokes Jones , Harrison Garber , Stefano Pasquali , Dhagash Mehta

Multi-agent large language model (LLM) systems are rapidly emerging as the dominant architecture for enterprise AI automation, yet production deployments exhibit failure rates between 41% and 86.7%, with nearly 79% of failures originating…

Artificial Intelligence · Computer Science 2026-04-21 Vivek Acharya

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Large language models (LLMs), despite their remarkable progress across various general domains, encounter significant barriers in medicine and healthcare. This field faces unique challenges such as domain-specific terminologies and…

Computation and Language · Computer Science 2024-06-06 Xiangru Tang , Anni Zou , Zhuosheng Zhang , Ziming Li , Yilun Zhao , Xingyao Zhang , Arman Cohan , Mark Gerstein

Purpose: The purpose of this study was to determine if an ensemble of multiple LLM agents could be used collectively to provide a more reliable assessment of a pixel-based AI triage tool than a single LLM. Methods: 29,766 non-contrast CT…

Computation and Language · Computer Science 2025-10-31 Adam E. Flanders , Yifan Peng , Luciano Prevedello , Robyn Ball , Errol Colak , Prahlad Menon , George Shih , Hui-Ming Lin , Paras Lakhani

Recent advancements in large language models (LLMs) revolutionize the field of intelligent agents, enabling collaborative multi-agent systems capable of tackling complex problems across various domains. However, the potential of conformity…

Computation and Language · Computer Science 2025-02-12 Zhiyuan Weng , Guikun Chen , Wenguan Wang

Prior Authorization delivers safe, appropriate, and cost-effective care that is medically justified with evidence-based guidelines. However, the process often requires labor-intensive manual comparisons between patient medical records and…

Artificial Intelligence · Computer Science 2024-07-09 Himanshu Pandey , Akhil Amod , Shivang
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