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Underlying cause of death coding from death certificates is a process that is nowadays undertaken mostly by humans with a potential assistance from expert systems such as the Iris software. It is as a consequence an expensive process that…

Reliable preclinical disease risk assessment is essential to move public healthcare from reactive treatment to proactive identification and prevention. However, image-based risk prediction algorithms often consider one condition at a time…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Dmitrii Seletkov , Sophie Starck , Ayhan Can Erdur , Yundi Zhang , Daniel Rueckert , Rickmer Braren

Accurate anatomical labeling of intracranial arteries is essential for cerebrovascular diagnosis and hemodynamic analysis but remains time-consuming and subject to interoperator variability. We present a deep learning-based framework for…

Cardiac digital twins provide a physics and physiology informed framework to deliver predictive and personalized medicine. However, high-fidelity multi-scale cardiac models remain a barrier to adoption due to their extensive computational…

Numerical Analysis · Mathematics 2023-06-09 Matteo Salvador , Marina Strocchi , Francesco Regazzoni , Luca Dede' , Steven Niederer , Alfio Quarteroni

Cognitive decline is highly heterogeneous across individuals, which complicates prognosis, trial design, and treatment planning. We present the Personalized Cognitive Decline Assessment Digital Twin (PCD-DT), a multimodal and…

Artificial Intelligence · Computer Science 2026-05-01 Bulent Soykan , Gulsah Hancerliogullari Koksalmis , Hsin-Hsiung Huang , Laura J. Brattain

Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…

Signal Processing · Electrical Eng. & Systems 2020-12-01 Dani Kiyasseh , Tingting Zhu , David A. Clifton

Physics-Informed Neural Networks (PINNs) combine deep learning with physical constraints for solving partial differential equations (PDEs), and are widely applied in fluid mechanics, heat transfer, and solid mechanics. However, PINN…

Machine Learning · Computer Science 2026-05-18 Xujia Chen , Xinyue Hu , Letian Chen , Daming Shi , Wenhui Fan

Heart diseases are the main international cause of human defunction. According to the WHO, nearly 18 million people decease each year because of heart diseases. Also considering the increase of medical data, much pressure is put on the…

Image and Video Processing · Electrical Eng. & Systems 2024-05-01 Andrés Bell-Navas , Nourelhouda Groun , María Villalba-Orero , Enrique Lara-Pezzi , Jesús Garicano-Mena , Soledad Le Clainche

Chronic Obstructive Pulmonary Disease (COPD) is the fourth leading cause of death worldwide. Yet, COPD diagnosis heavily relies on spirometric examination as well as functional airway limitation, which may cause a considerable portion of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yiqing Shen , Baiyun Liu , Ruize Yu , Yudong Wang , Shaokang Wang , Jiangfen Wu , Weidao Chen

Intracranial aneurysms remain a major cause of neurological morbidity and mortality worldwide, where rupture risk is tightly coupled to local hemodynamics particularly wall shear stress and oscillatory shear index. Conventional…

Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

Kinetic modeling enables \textit{in vivo} quantification of tracer uptake and glucose metabolism in [${}^{18}$F]Fluorodeoxyglucose ([${}^{18}$F]FDG) dynamic positron emission tomography (dPET) imaging of mice. However, kinetic modeling…

Quantitative Methods · Quantitative Biology 2025-10-27 Christian Salomonsen , Kristoffer K. Wickstrøm , Samuel Kuttner , Elisabeth Wetzer

A clinically actionable Cardiac Digital Twin (CDT) should reconstruct individualised cardiac anatomy and physiology, update its internal state from multimodal signals, and enable a broad range of downstream simulations beyond isolated…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Haofan Wu , Nay Aung , Theodoros N. Arvanitis , Joao A. C. Lima , Steffen E. Petersen , Le Zhang

Accurate prediction of protein-ligand binding affinity is crucial for rapid and efficient drug development. Recently, the importance of predicting binding affinity has led to increased attention on research that models the three-dimensional…

Machine Learning · Computer Science 2024-07-17 Seungyeon Choi , Sangmin Seo , Sanghyun Park

Particle Image Velocimetry (PIV) data is a valuable asset in fluid mechanics. It is capable of visualizing flow structures even in complex physics scenarios, such as the flow at the exit of the rotor of a centrifugal fan. Machine learning…

Fluid Dynamics · Physics 2024-08-01 Maryam Soltani , Ghasem Akbari , Nader Montazerin

Supervised machine learning provides state-of-the-art solutions to a wide range of computer vision problems. However, the need for copious labelled training data limits the capabilities of these algorithms in scenarios where such input is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 András Kalapos , Bálint Gyires-Tóth

We introduce a novel methodology that leverages the strength of Physics-Informed Neural Networks (PINNs) to address the counterdiabatic (CD) protocol in the optimization of quantum circuits comprised of systems with $N_{Q}$ qubits. The…

Cardiovascular diseases (CVD) are the leading cause of death worldwide, with coronary artery disease (CAD) comprising the largest subcategory of CVDs. Recently, there has been increased focus on detecting CAD using phonocardiogram (PCG)…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-07 Milan Marocchi , Matthew Fynn , Yue Rong

Computational fluid dynamics (CFD) can be used to simulate vascular haemodynamics and analyse potential treatment options. CFD has shown to be beneficial in improving patient outcomes. However, the implementation of CFD for routine clinical…

Early diagnosis and intervention are clinically considered the paramount part of treating cerebral palsy (CP), so it is essential to design an efficient and interpretable automatic prediction system for CP. We highlight a significant…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Haozheng Zhang , Hubert P. H. Shum , Edmond S. L. Ho
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