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Optimization drives advances in quantum science and machine learning, yet most generative models aim to mimic data rather than to discover optimal answers to challenging problems. Here we present a variational generative optimization…

Quantum Physics · Physics 2025-08-19 Lingxia Zhang , Xiaodie Lin , Peidong Wang , Kaiyan Yang , Xiao Zeng , Zhaohui Wei , Zizhu Wang

The Boltzmann machine provides a useful framework to learn highly complex, multimodal and multiscale data distributions that occur in the real world. The default method to learn its parameters consists of minimizing the Kullback-Leibler…

Machine Learning · Statistics 2015-07-09 Grégoire Montavon , Klaus-Robert Müller , Marco Cuturi

The development of quantum technologies relies on creating and manipulating quantum systems of increasing complexity, with key applications in computation, simulation, and sensing. This poses severe challenges in efficient control,…

Quantum Physics · Physics 2025-09-09 Hailan Ma , Bo Qi , Ian R. Petersen , Re-Bing Wu , Herschel Rabitz , Daoyi Dong

In recent proposals of quantum circuit models for generative tasks, the discussion about their performance has been limited to their ability to reproduce a known target distribution. For example, expressive model families such as Quantum…

Recently, bicycle-sharing systems have been implemented in numerous cities, becoming integral to daily life. However, a prevalent issue arises when intensive commuting demand leads to bicycle shortages in specific areas and at particular…

Quantum Physics · Physics 2026-02-10 Fumio Nemoto , Nobuyuki Koike , Daichi Sato , Yuuta Kawaai , Masayuki Ohzeki

The quest for improved sampling methods to solve statistical mechanics problems of physical and chemical interest proceeds with renewed efforts since the invention of the Metropolis algorithm, in 1953. In particular, the understanding of…

Quantum Physics · Physics 2021-08-27 Guglielmo Mazzola

The goal of this paper is to apply the collection of mathematical tools known as the "method of arbitrary functions" to analyze how probability arises from quantum dynamics. We argue that in a toy model of quantum measurement the Born rule…

Quantum Physics · Physics 2024-09-26 Liam Bonds , Brooke Burson , Kade Cicchella , Benjamin H. Feintzeig , Lynnx , Alia Yusaini

Variational autoencoders (VAEs) are powerful generative models with the salient ability to perform inference. Here, we introduce a quantum variational autoencoder (QVAE): a VAE whose latent generative process is implemented as a quantum…

Modern generative machine learning models demonstrate surprising ability to create realistic outputs far beyond their training data, such as photorealistic artwork, accurate protein structures, or conversational text. These successes…

Machine Learning · Computer Science 2024-01-17 William Gilpin

Variational neural network models have achieved remarkable success in solving ground-state problems of quantum many-body systems. However, addressing classical and quantum spin glasses remains challenging, as disorder and energy frustration…

Disordered Systems and Neural Networks · Physics 2026-05-18 Luca Leone , Arka Dutta , Markus Heyl , Enrico Prati , Pietro Torta

Mainstream machine-learning techniques such as deep learning and probabilistic programming rely heavily on sampling from generally intractable probability distributions. There is increasing interest in the potential advantages of using…

Quantum Physics · Physics 2018-01-29 Marcello Benedetti , John Realpe-Gómez , Rupak Biswas , Alejandro Perdomo-Ortiz

The complete learning of an $n$-qubit quantum state requires samples exponentially in $n$. Several works consider subclasses of quantum states that can be learned in polynomial sample complexity such as stabilizer states or high-temperature…

Quantum Physics · Physics 2023-09-19 Liming Zhao , Naixu Guo , Ming-Xing Luo , Patrick Rebentrost

Learning representations of molecular structures using deep learning is a fundamental problem in molecular property prediction tasks. Molecules inherently exist in the real world as three-dimensional structures; furthermore, they are not…

Machine Learning · Computer Science 2024-01-22 Daiki Koge , Naoaki Ono , Shigehiko Kanaya

Inference is the task of drawing conclusions about unobserved variables given observations of related variables. Applications range from identifying diseases from symptoms to classifying economic regimes from price movements. Unfortunately,…

Generative models offer a direct way of modeling complex data. Energy-based models attempt to encode the statistical correlations observed in the data at the level of the Boltzmann weight associated with an energy function in the form of a…

Disordered Systems and Neural Networks · Physics 2024-04-10 Aurélien Decelle , Cyril Furtlehner , Alfonso De Jesus Navas Gómez , Beatriz Seoane

We consider how the Born rule, a fundamental principle of quantum mechanics, can be tested for particles created on the shortest timescales ($\sim10^{-25}\,\mathrm{s}$) currently accessible at high-energy colliders. We focus on targeted…

High Energy Physics - Phenomenology · Physics 2026-01-05 Antony Valentini , Mira Varma

Works in quantum machine learning (QML) over the past few years indicate that QML algorithms can function just as well as their classical counterparts, and even outperform them in some cases. Among the corpus of recent work, many current…

Machine Learning · Computer Science 2023-05-18 Joseph Lindsay , Ramtin Zand

We introduce and motivate generative modeling as a central task for machine learning and provide a critical view of the algorithms which have been proposed for solving this task. We overview how generative modeling can be defined…

Machine Learning · Computer Science 2021-03-02 Alex Lamb

Generative models for quantum data pose significant challenges but hold immense potential in fields such as chemoinformatics and quantum physics. Quantum denoising diffusion probabilistic models (QuDDPMs) enable efficient learning of…

Quantum Physics · Physics 2026-03-03 Quoc Hoan Tran , Koki Chinzei , Yasuhiro Endo , Hirotaka Oshima

It is widely known that Boltzmann machines are capable of representing arbitrary probability distributions over the values of their visible neurons, given enough hidden ones. However, sampling -- and thus training -- these models can be…

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