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Electroencephalography (EEG) foundation models have shown strong potential for learning generalizable representations from large-scale neural data, yet their clinical deployment is hindered by distribution shifts across clinical settings,…

Machine Learning · Computer Science 2026-04-21 Gabriel Jason Lee , Jathurshan Pradeepkumar , Jimeng Sun

Deep learning-based medical image segmentation models often face performance degradation when deployed across various medical centers, largely due to the discrepancies in data distribution. Test Time Adaptation (TTA) methods, which adapt…

Computer Vision and Pattern Recognition · Computer Science 2024-05-15 Shishuai Hu , Zehui Liao , Zeyou Liu , Yong Xia

Test-Time Adaptation (TTA) has recently emerged as a promising approach for tackling the robustness challenge under distribution shifts. However, the lack of consistent settings and systematic studies in prior literature hinders thorough…

Machine Learning · Computer Science 2023-06-07 Hao Zhao , Yuejiang Liu , Alexandre Alahi , Tao Lin

Medical image segmentation is critical for clinical diagnosis, treatment planning, and monitoring, yet segmentation models often struggle with uncertainties stemming from occlusions, ambiguous boundaries, and variations in imaging devices.…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Xiao Ma , Yuhui Tao , Zetian Zhang , Yuhan Zhang , Xi Wang , Sheng Zhang , Zexuan Ji , Yizhe Zhang , Qiang Chen , Guang Yang

Deploying multi-sequence magnetic resonance imaging (MRI) segmentation models to new clinical environments is challenging due to variations in scanners and acquisition protocols. Although existing TTA methods handle basic per-modality…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Zhipeng Deng , Jiale Zhou , Wenhan Jiang , Haolin Wang , Xun Lin , Yafei Ou , Yefeng Zheng

Supervised learning is well-known to fail at generalization under distribution shifts. In typical clinical settings, the source data is inaccessible and the target distribution is represented with a handful of samples: adaptation can only…

Computer Vision and Pattern Recognition · Computer Science 2022-05-18 Mathilde Bateson , Hervé Lombaert , Ismail Ben Ayed

Recently, test-time adaptation has attracted wide interest in the context of vision-language models for image classification. However, to the best of our knowledge, the problem is completely overlooked in dense prediction tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Mehrdad Noori , David Osowiechi , Gustavo Adolfo Vargas Hakim , Ali Bahri , Moslem Yazdanpanah , Sahar Dastani , Farzad Beizaee , Ismail Ben Ayed , Christian Desrosiers

Performance of convolutional neural networks (CNNs) in image analysis tasks is often marred in the presence of acquisition-related distribution shifts between training and test images. Recently, it has been proposed to tackle this problem…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Neerav Karani , Georg Brunner , Ertunc Erdil , Simin Fei , Kerem Tezcan , Krishna Chaitanya , Ender Konukoglu

Machine learning methods strive to acquire a robust model during the training process that can effectively generalize to test samples, even in the presence of distribution shifts. However, these methods often suffer from performance…

Machine Learning · Computer Science 2024-12-13 Jian Liang , Ran He , Tieniu Tan

Deep-learning models have been successful in biomedical image segmentation. To generalize for real-world deployment, test-time augmentation (TTA) methods are often used to transform the test image into different versions that are hopefully…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Kangxian Xie , Siyu Huang , Sebastian Andres Cajas Ordonez , Hanspeter Pfister , Donglai Wei

Medical image segmentation plays a crucial role in clinical diagnosis and treatment planning. Although models based on convolutional neural networks (CNNs) and Transformers have achieved remarkable success in medical image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Jiashu Xu

Test-Time Adaptation (TTA) has emerged as a promising solution for adapting a source model to unseen medical sites using unlabeled test data, due to the high cost of data annotation. Existing TTA methods consider scenarios where data from…

Computer Vision and Pattern Recognition · Computer Science 2025-07-04 Wei Li , Jingyang Zhang , Lihao Liu , Guoan Wang , Junjun He , Yang Chen , Lixu Gu

Reliable brain tumor segmentation in MRI is indispensable for treatment planning and outcome monitoring, yet models trained on curated benchmarks often fail under domain shifts arising from scanner and protocol variability as well as…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Yuanhan Wang , Yifei Chen , Shuo Jiang , Wenjing Yu , Mingxuan Liu , Beining Wu , Jinying Zong , Feiwei Qin , Changmiao Wang , Qiyuan Tian

The practical utility of Speech Emotion Recognition (SER) systems is undermined by their fragility to domain shifts, such as speaker variability, the distinction between acted and naturalistic emotions, and cross-corpus variations. While…

Audio and Speech Processing · Electrical Eng. & Systems 2026-01-26 Jiaheng Dong , Hong Jia , Ting Dang

Medical image segmentation is vital for clinical diagnosis and quantitative analysis, yet remains challenging due to the heterogeneity of imaging modalities and the high cost of pixel-level annotations. Although general interactive…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yujie Lu , Jingwen Li , Sibo Ju , Yanzhou Su , he yao , Yisong Liu , Min Zhu , Junlong Cheng

Reliable long-term decoding of surface electromyography (EMG) is hindered by signal drift caused by electrode shifts, muscle fatigue, and posture changes. While state-of-the-art models achieve high intra-session accuracy, their performance…

Machine Learning · Computer Science 2026-01-08 Nia Touko , Matthew O A Ellis , Cristiano Capone , Alessio Burrello , Elisa Donati , Luca Manneschi

This article presents a comprehensive survey of online test-time adaptation (OTTA), focusing on effectively adapting machine learning models to distributionally different target data upon batch arrival. Despite the recent proliferation of…

Artificial Intelligence · Computer Science 2024-07-19 Zixin Wang , Yadan Luo , Liang Zheng , Zhuoxiao Chen , Sen Wang , Zi Huang

Deep neural networks have useful applications in many different tasks, however their performance can be severely affected by changes in the data distribution. For example, in the biomedical field, their performance can be affected by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-30 Pedro Vianna , Muawiz Chaudhary , Paria Mehrbod , An Tang , Guy Cloutier , Guy Wolf , Michael Eickenberg , Eugene Belilovsky

Encountering shifted data at test time is a ubiquitous challenge when deploying predictive models. Test-time adaptation (TTA) methods address this issue by continuously adapting a deployed model using only unlabeled test data. While TTA can…

Machine Learning · Computer Science 2025-11-11 Mona Schirmer , Metod Jazbec , Christian A. Naesseth , Eric Nalisnick

Purpose: Applying pre-trained medical deep learning segmentation models on out-of-domain images often yields predictions of insufficient quality. In this study, we propose to use a powerful generalizing descriptor along with augmentation to…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Christian Weihsbach , Christian N. Kruse , Alexander Bigalke , Mattias P. Heinrich