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Aim: This study aims to enhance interpretability and explainability of multi-modal prediction models integrating imaging and tabular patient data. Methods: We adapt the xAI methods Grad-CAM and Occlusion to multi-modal, partly interpretable…

Image and Video Processing · Electrical Eng. & Systems 2025-04-10 Jonas Brändli , Maurice Schneeberger , Lisa Herzog , Loran Avci , Nordin Dari , Martin Häansel , Hakim Baazaoui , Pascal Bühler , Susanne Wegener , Beate Sick

Following successful large-vessel recanalization via endovascular thrombectomy (EVT) for acute ischemic stroke (AIS), some patients experience a complication known as no-reflow, defined by persistent microvascular hypoperfusion that…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Shreeram Athreya , Carlos Olivares , Ameera Ismail , Kambiz Nael , William Speier , Corey Arnold

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

In this paper, we demonstrate the feasibility and performance of deep residual neural networks for volumetric segmentation of irreversibly damaged brain tissue lesions on T1-weighted MRI scans for chronic stroke patients. A total of 239…

Image and Video Processing · Electrical Eng. & Systems 2019-11-27 Naofumi Tomita , Steven Jiang , Matthew E. Maeder , Saeed Hassanpour

Background: Stroke is second-leading cause of disability and death among adults. Approximately 17 million people suffer from a stroke annually, with about 85% being ischemic strokes. Predicting mortality of ischemic stroke patients in…

Machine Learning · Computer Science 2024-09-04 Armin Abdollahi , Negin Ashrafi , Maryam Pishgar

Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural cerebral abnormalities. For covert lesions, machine learning…

Recent randomised clinical trials have shown that patients with ischaemic stroke {due to occlusion of a large intracranial blood vessel} benefit from endovascular thrombectomy. However, predicting outcome of treatment in an individual…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Zeynel A. Samak , Philip Clatworthy , Majid Mirmehdi

Deep learning and multi-modal fusion have demonstrated transformative potential in medical diagnosis by integrating diverse data sources. However, accurate prognosis for ischemic stroke remains challenging due to limitations in existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Liren Chen , Lidong Sun , Mingyan Huang , Junzhe Tang , Yinghui Zhu , Guanjie Wang , Yiqing Xia , Ting Xiao

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

In an emergency room (ER) setting, stroke triage or screening is a common challenge. A quick CT is usually done instead of MRI due to MRI's slow throughput and high cost. Clinical tests are commonly referred to during the process, but the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Tongan Cai , Haomiao Ni , Mingli Yu , Xiaolei Huang , Kelvin Wong , John Volpi , James Z. Wang , Stephen T. C. Wong

Accurate and generalisable segmentation of stroke lesions from magnetic resonance imaging (MRI) is essential for advancing clinical research, prognostic modelling, and personalised interventions. Although deep learning has improved…

Quantitative Methods · Quantitative Biology 2026-02-11 Tammar Truzman , Matthew A. Lambon Ralph , Ajay D. Halai

Stroke is among the top three causes of death worldwide, and accurate identification of ischemic stroke lesion boundaries from imaging is critical for diagnosis and treatment. The main imaging modalities used include magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Juampablo E. Heras Rivera , Hitender Oswal , Tianyi Ren , Yutong Pan , William Henry , Caitlin M. Neher , Mehmet Kurt

Accurate preoperative prediction of erectile dysfunction (ED) is important for counseling patients undergoing radical prostatectomy. While clinical features are established predictors, the added value of preoperative MRI remains…

The patient with ischemic stroke can benefit most from the earliest possible definitive diagnosis. While the high quality medical resources are quite scarce across the globe, an automated diagnostic tool is expected in analyzing the…

Computer Vision and Pattern Recognition · Computer Science 2018-03-16 Zhiyang Liu , Chen Cao , Shuxue Ding , Tong Han , Hong Wu , Sheng Liu

At present, the majority of the proposed Deep Learning (DL) methods provide point predictions without quantifying the models uncertainty. However, a quantification of the reliability of automated image analysis is essential, in particular…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Lisa Herzog , Elvis Murina , Oliver Dürr , Susanne Wegener , Beate Sick

Computed Tomography (CT) is commonly used to image acute ischemic stroke (AIS) patients, but its interpretation by radiologists is time-consuming and subject to inter-observer variability. Deep learning (DL) techniques can provide automated…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

Ischemic stroke is a common disease in the elderly population, which can cause long-term disability and even death. However, the time window for treatment of ischemic stroke in its acute stage is very short. To fast localize and…

Image and Video Processing · Electrical Eng. & Systems 2020-09-22 Bin Zhao , Shuxue Ding , Hong Wu , Guohua Liu , Chen Cao , Song Jin , Zhiyang Liu

Appropriate antithrombotic therapy for patients with atrial fibrillation (AF) requires assessment of ischemic stroke and bleeding risks. However, risk stratification schemas such as CHA2DS2-VASc and HAS-BLED have modest predictive capacity…

Artificial intelligence holds strong potential to support clinical decision making in intensive care units where timely and accurate risk assessment is critical. However, many existing models focus on isolated outcomes or limited data…

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang