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Honesty is a fundamental principle for aligning large language models (LLMs) with human values, requiring these models to recognize what they know and don't know and be able to faithfully express their knowledge. Despite promising, current…

Computation and Language · Computer Science 2024-09-30 Siheng Li , Cheng Yang , Taiqiang Wu , Chufan Shi , Yuji Zhang , Xinyu Zhu , Zesen Cheng , Deng Cai , Mo Yu , Lemao Liu , Jie Zhou , Yujiu Yang , Ngai Wong , Xixin Wu , Wai Lam

This paper provides a primer on Large Language Models (LLMs) and identifies their strengths, limitations, applications and research directions. It is intended to be useful to those in academia and industry who are interested in gaining an…

Computation and Language · Computer Science 2024-12-09 Sandra Johnson , David Hyland-Wood

Large Language Models (LLMs) have taken Knowledge Representation -- and the world -- by storm. This inflection point marks a shift from explicit knowledge representation to a renewed focus on the hybrid representation of both explicit…

Large language models (LLMs) are beginning to reshape how chemists plan and run reactions in organic synthesis. Trained on millions of reported transformations, these text-based models can propose synthetic routes, forecast reaction…

Artificial Intelligence · Computer Science 2025-08-08 Kartar Kumar Lohana Tharwani , Rajesh Kumar , Sumita , Numan Ahmed , Yong Tang

With careful manipulation, malicious agents can reverse engineer private information encoded in pre-trained language models. Security concerns motivate the development of quantum pre-training. In this work, we propose a highly Portable…

Machine Learning · Computer Science 2023-02-28 Shuyue Stella Li , Xiangyu Zhang , Shu Zhou , Hongchao Shu , Ruixing Liang , Hexin Liu , Leibny Paola Garcia

Large language models (LLMs) represent a new paradigm for processing unstructured data, with applications across an unprecedented range of domains. In this paper, we address, through two arguments, whether the development and application of…

Methodology · Statistics 2026-02-03 Weijie Su

Despite impressive performance on language modelling and complex reasoning tasks, Large Language Models (LLMs) fall short on the same tasks in uncommon settings or with distribution shifts, exhibiting a lack of generalisation ability. By…

Computation and Language · Computer Science 2024-09-11 Gaël Gendron , Bao Trung Nguyen , Alex Yuxuan Peng , Michael Witbrock , Gillian Dobbie

Large Language Models (LLMs) have seen rapid advancements in recent years, with models like ChatGPT and DeepSeek, showcasing their remarkable capabilities across diverse domains. While substantial research has been conducted on LLMs in…

Machine Learning · Computer Science 2026-03-31 Licheng Zhang , Bach Le , Naveed Akhtar , Siew-Kei Lam , Tuan Ngo

Large language models (LLMs) promise transformative change to fields as diverse as medical diagnosis, legal services, and software development. One reason for such an impact is LLMs' ability to make highly technical endeavors more…

Quantum Physics · Physics 2025-06-24 Elena R. Henderson , Jessie M. Henderson , Joshua Ange , Mitchell A. Thornton

Large Language Models (LLMs) are becoming increasingly popular in pervasive computing due to their versatility and strong performance. However, despite their ubiquitous use, the exact mechanisms underlying their outstanding performance…

Computation and Language · Computer Science 2026-02-02 Alhassan Abdelhalim , Janick Edinger , Sören Laue , Michaela Regneri

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Large language models (LLMs) have shown remarkable proficiency in generating text, benefiting from extensive training on vast textual corpora. However, LLMs may also acquire unwanted behaviors from the diverse and sensitive nature of their…

Computation and Language · Computer Science 2025-03-24 Zhiwei Zhang , Fali Wang , Xiaomin Li , Zongyu Wu , Xianfeng Tang , Hui Liu , Qi He , Wenpeng Yin , Suhang Wang

Large language models (LLMs) encode vast amounts of knowledge during pre-training (parametric knowledge, or PK) and can further be enhanced by incorporating contextual knowledge (CK). Can LLMs effectively integrate their internal PK with…

Computation and Language · Computer Science 2024-10-16 Sitao Cheng , Liangming Pan , Xunjian Yin , Xinyi Wang , William Yang Wang

Human bilinguals often use similar brain regions to process multiple languages, depending on when they learned their second language and their proficiency. In large language models (LLMs), how are multiple languages learned and encoded? In…

Computation and Language · Computer Science 2025-05-26 Jannik Brinkmann , Chris Wendler , Christian Bartelt , Aaron Mueller

Large Language Models have demonstrated the ability to generalize well at many levels across domains, modalities, and even shown in-context learning capabilities. This enables research questions regarding how they can be used to encode…

Computation and Language · Computer Science 2025-11-19 Kiera McCormick , Rafael Martínez-Galarza

For the first time, physicists are in the position to precisely study a fully relativistic quantum field theory: Quantum ChromoDynamics (QCD). QCD is a central element of the Standard Model and provides the theoretical framework for…

Nuclear Experiment · Physics 2014-05-28 Richard G. Milner

The capabilities of large language models (LLMs) have expanded beyond natural language processing to scientific prediction tasks, including molecular property prediction. However, their effectiveness in in-context learning remains…

The increasing complexity of software systems has driven significant advancements in program analysis, as traditional methods unable to meet the demands of modern software development. To address these limitations, deep learning techniques,…

Software Engineering · Computer Science 2025-02-27 Jiayimei Wang , Tao Ni , Wei-Bin Lee , Qingchuan Zhao

Large language models (LLMs) demonstrate remarkable emergent abilities to perform in-context learning across various tasks, including time series forecasting. This work investigates LLMs' ability to estimate probability density functions…

Machine Learning · Computer Science 2025-03-05 Toni J. B. Liu , Nicolas Boullé , Raphaël Sarfati , Christopher J. Earls

Accurately quantifying uncertainty in large language models (LLMs) is crucial for their reliable deployment, especially in high-stakes applications. Current state-of-the-art methods for measuring semantic uncertainty in LLMs rely on strict…

Machine Learning · Computer Science 2024-10-31 Yashvir S. Grewal , Edwin V. Bonilla , Thang D. Bui
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