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Paediatric Acute Myeloid Leukemia is a complex adaptive ecosystem with high morbidity. Current trajectory inference algorithms struggle to predict causal dynamics in AML progression, including relapse and recurrence risk. We propose a…

Quantitative Methods · Quantitative Biology 2025-08-20 Abicumaran Uthamacumaran , Hector Zenil

Several problems in neuroimaging and beyond require inference on the parameters of multi-task sparse hierarchical regression models. Examples include M/EEG inverse problems, neural encoding models for task-based fMRI analyses, and climate…

Machine learning (ML) is redefining what is possible in data-intensive fields of science and engineering. However, applying ML to problems in the physical sciences comes with a unique set of challenges: scientists want physically…

Computational Physics · Physics 2020-07-06 Kathleen Champion , Peng Zheng , Aleksandr Y. Aravkin , Steven L. Brunton , J. Nathan Kutz

Machine learning (ML) models show strong promise for new biomedical prediction tasks, but concerns about trustworthiness have hindered their clinical adoption. In particular, it is often unclear whether a model relies on true clinical cues…

Machine Learning · Computer Science 2026-01-13 Dushan N. Wadduwage , Dineth Jayakody , Leonidas Zimianitis

Probabilistic logical models are a core component of neurosymbolic AI and are important in their own right for tasks that require high explainability. Unlike neural networks, logical theories that underlie the model are often handcrafted…

Artificial Intelligence · Computer Science 2025-10-07 Jonathan Feldstein , Dominic Phillips , Efthymia Tsamoura

While advancements in NLP have significantly improved the performance of Large Language Models (LLMs) on tasks requiring vertical thinking, their lateral thinking capabilities remain under-explored and challenging to measure due to the…

Computation and Language · Computer Science 2024-10-10 Qi Chen , Bowen Zhang , Gang Wang , Qi Wu

In the data-driven era, large-scale datasets are routinely collected and analyzed using machine learning (ML) and artificial intelligence (AI) to inform decisions in high-stakes domains such as healthcare, employment, and criminal justice,…

Machine Learning · Computer Science 2026-05-13 Drago Plecko

Probabilistic Graphical Models (PGM) are very useful in the fields of machine learning and data mining. The crucial limitation of those models,however, is the scalability. The Bayesian Network, which is one of the most common PGMs used in…

Probabilistic graphical models (PGMs) are widely used to discover latent structure in data, but their success hinges on selecting an appropriate model design. In practice, model specification is difficult and often requires iterative…

Machine Learning · Computer Science 2026-04-08 Kevin Zhang , Yixin Wang

Model interpretability has become an important problem in machine learning (ML) due to the increased effect that algorithmic decisions have on humans. Counterfactual explanations can help users understand not only why ML models make certain…

Machine Learning · Computer Science 2021-12-20 Ana Lucic , Harrie Oosterhuis , Hinda Haned , Maarten de Rijke

This paper introduces a novel Proxy-Enhanced Correlated Random Effects Double Machine Learning (P-CRE-DML) framework to estimate causal effects in panel data with non-linearities and unobserved heterogeneity. Combining Double Machine…

Econometrics · Economics 2025-07-01 Amarendra Sharma

We propose a sparse coefficient estimation and automated model selection procedure for autoregressive (AR) processes with heavy-tailed innovations based on penalized conditional maximum likelihood. Under mild moment conditions on the…

Methodology · Statistics 2013-09-24 Hailin Sang , Yan Sun

Computational analysis of time-course data with an underlying causal structure is needed in a variety of domains, including neural spike trains, stock price movements, and gene expression levels. However, it can be challenging to determine…

Artificial Intelligence · Computer Science 2012-05-14 Samantha Kleinberg , Bud Mishra

Artificial intelligence applications such as industrial robotics, military surveillance, and hazardous environment clean-up, require situation understanding based on partial, uncertain, and ambiguous or erroneous evidence. It is necessary…

Artificial Intelligence · Computer Science 2013-04-15 Tod S. Levitt

Learning-based signal processing systems increasingly support high-stakes medical decisions using heterogeneous biomedical signals, including medical images, physiological time series, and clinical records. Despite strong predictive…

Signal Processing · Electrical Eng. & Systems 2026-03-02 Surajit Das , Maxine Tan

Signal modeling lies at the core of numerous signal and image processing applications. A recent approach that has drawn considerable attention is sparse representation modeling, in which the signal is assumed to be generated as a…

Information Theory · Computer Science 2016-11-17 Tomer Peleg , Yonina C. Eldar , Michael Elad

Algorithmic decisions about individuals require predictions that are not only accurate but also fair with respect to sensitive attributes such as gender and race. Causal notions of fairness align with legal requirements, yet many methods…

Machine Learning · Statistics 2026-03-02 Yoichi Chikahara

Collaborative machine learning (ML) is an appealing paradigm to build high-quality ML models by training on the aggregated data from many parties. However, these parties are only willing to share their data when given enough incentives,…

Machine Learning · Computer Science 2020-10-27 Rachael Hwee Ling Sim , Yehong Zhang , Mun Choon Chan , Bryan Kian Hsiang Low

The question of how individual patient data from cohort studies or historical clinical trials can be leveraged for designing more powerful, or smaller yet equally powerful, clinical trials becomes increasingly important in the era of…

Methodology · Statistics 2022-09-01 Sandra Siegfried , Stephen Senn , Torsten Hothorn

Symbolic regression searches for analytic expressions that accurately describe studied phenomena. The main attraction of this approach is that it returns an interpretable model that can be insightful to users. Historically, the majority of…