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Accurate brain lesion delineation is important for planning neurosurgical treatment. Automatic brain lesion segmentation methods based on convolutional neural networks have demonstrated remarkable performance. However, neural network…

Image and Video Processing · Electrical Eng. & Systems 2024-08-20 Jiayu Huo , Sebastien Ourselin , Rachel Sparks

Unsupervised learning can discover various unseen abnormalities, relying on large-scale unannotated medical images of healthy subjects. Towards this, unsupervised methods reconstruct a 2D/3D single medical image to detect outliers either in…

Computer Vision and Pattern Recognition · Computer Science 2020-10-13 Changhee Han , Leonardo Rundo , Kohei Murao , Tomoyuki Noguchi , Yuki Shimahara , Zoltan Adam Milacski , Saori Koshino , Evis Sala , Hideki Nakayama , Shinichi Satoh

Diagnosing Brain Tumor with the aid of Magnetic Resonance Imaging (MRI) has gained enormous prominence over the years, primarily in the field of medical science. Detection and/or partitioning of brain tumors solely with the aid of MR…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Md. Abu Bakr Siddique , Shadman Sakib , Mohammad Mahmudur Rahman Khan , Abyaz Kader Tanzeem , Madiha Chowdhury , Nowrin Yasmin

It is widely recognized that deep neural networks are sensitive to bias in the data. This means that during training these models are likely to learn spurious correlations between data and labels, resulting in limited generalization…

Machine Learning · Computer Science 2024-12-06 Vito Paolo Pastore , Massimiliano Ciranni , Davide Marinelli , Francesca Odone , Vittorio Murino

Deep learning algorithms have accounted for the rapid acceleration of research in artificial intelligence in medical image analysis, interpretation, and segmentation with many potential applications across various sub disciplines in…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Shanaka Ramesh Gunasekara , HNTK Kaldera , Maheshi B. Dissanayake

Automatic segmentation of brain tumors in intra-operative ultrasound (iUS) images could facilitate localization of tumor tissue during resection surgery. The lack of large annotated datasets limits the current models performances. In this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Mathilde Faanes , Ragnhild Holden Helland , Ole Solheim , Sébastien Muller , Ingerid Reinertsen

The goal of unsupervised anomaly segmentation (UAS) is to detect the pixel-level anomalies unseen during training. It is a promising field in the medical imaging community, e.g, we can use the model trained with only healthy data to segment…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Chenxin Li , Yunlong Zhang , Jiongcheng Li , Yue Huang , Xinghao Ding

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

Although deep learning has been applied to successfully address many data mining problems, relatively limited work has been done on deep learning for anomaly detection. Existing deep anomaly detection methods, which focus on learning new…

Machine Learning · Computer Science 2019-11-21 Guansong Pang , Chunhua Shen , Anton van den Hengel

Unsupervised anomaly detection in brain images is crucial for identifying injuries and pathologies without access to labels. However, the accurate localization of anomalies in medical images remains challenging due to the inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Farzad Beizaee , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Reliable automated analysis of Optical Coherence Tomography (OCT) imaging is crucial for diagnosing retinal disorders but faces a critical barrier: the need for expensive, labor-intensive expert annotations. Supervised deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Tania Haghighi , Sina Gholami , Hamed Tabkhi , Minhaj Nur Alam

Given a long list of anomaly detection algorithms developed in the last few decades, how do they perform with regard to (i) varying levels of supervision, (ii) different types of anomalies, and (iii) noisy and corrupted data? In this work,…

Machine Learning · Computer Science 2022-09-20 Songqiao Han , Xiyang Hu , Hailiang Huang , Mingqi Jiang , Yue Zhao

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

Diffusion magnetic resonance imaging (dMRI) is a crucial technique in neuroimaging studies, allowing for the non-invasive probing of the underlying structures of brain tissues. Clinical dMRI data is susceptible to various artifacts during…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Sheng Chen , Zihao Tang , Xinyi Wang , Chenyu Wang , Weidong Cai

Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Adrian V. Dalca , Evan Yu , Polina Golland , Bruce Fischl , Mert R. Sabuncu , Juan Eugenio Iglesias

Unsupervised Anomaly Detection (UAD) methods rely on healthy data distributions to identify anomalies as outliers. In brain MRI, a common approach is reconstruction-based UAD, where generative models reconstruct healthy brain MRIs, and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

In this paper, we study unsupervised anomaly detection algorithms that learn a neural network representation, i.e. regular patterns of normal data, which anomalies are deviating from. Inspired by a similar concept in engineering, we refer…

Machine Learning · Computer Science 2025-11-12 Simon Klüttermann , Tim Katzke , Emmanuel Müller

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal