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The need for training data can impede the adoption of novel imaging modalities for learning-based medical image analysis. Domain adaptation methods partially mitigate this problem by translating training data from a related source domain to…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Eleni Chiou , Francesco Giganti , Shonit Punwani , Iasonas Kokkinos , Eleftheria Panagiotaki

Despite the widespread use of deep learning methods for semantic segmentation of images that are acquired from a single source, clinicians often use multi-domain data for a detailed analysis. For instance, CT and MRI have advantages over…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Bora Baydar , Savas Ozkan , A. Emre Kavur , N. Sinem Gezer , M. Alper Selver , Gozde Bozdagi Akar

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

Retinal vessel segmentation serves as a critical prerequisite for automated diagnosis of retinal pathologies. While recent advances in Convolutional Neural Networks (CNNs) have demonstrated promising performance in this task, significant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Zhanqiang Guo , Jianjiang Feng , Jie Zhou

Traditional domain generalization methods often rely on domain alignment to reduce inter-domain distribution differences and learn domain-invariant representations. However, domain shifts are inherently difficult to eliminate, which limits…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuheng Xu , Taiping Zhang

Open-set single-source domain generalization aims to use a single-source domain to learn a robust model that can be generalized to unknown target domains with both domain shifts and label shifts. The scarcity of the source domain and the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Pengkun Jiao , Na Zhao , Jingjing Chen , Yu-Gang Jiang

The success of deep learning has set new benchmarks for many medical image analysis tasks. However, deep models often fail to generalize in the presence of distribution shifts between training (source) data and test (target) data. One…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Dwarikanath Mahapatra

Multi-Source Domain Generalization (DG) is the task of training on multiple source domains and achieving high classification performance on unseen target domains. Recent methods combine robust features from web-scale pretrained backbones…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Piotr Teterwak , Kuniaki Saito , Theodoros Tsiligkaridis , Bryan A. Plummer , Kate Saenko

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Domain generalization (DG) is an important problem that learns a model which generalizes to unseen test domains leveraging one or more source domains, under the assumption of shared label spaces. However, most DG methods assume access to…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Christopher Liao , Christian So , Theodoros Tsiligkaridis , Brian Kulis

Currently, cross-scene hyperspectral image (HSI) classification has drawn increasing attention. It is necessary to train a model only on source domain (SD) and directly transferring the model to target domain (TD), when TD needs to be…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Yuxiang Zhang , Wei Li , Weidong Sun , Ran Tao , Qian Du

Domain generalization (DG) aims to train a model to perform well in unseen domains under different distributions. This paper considers a more realistic yet more challenging scenario,namely Single Domain Generalization (Single-DG), where…

Computer Vision and Pattern Recognition · Computer Science 2022-12-05 Jiajin Zhang , Hanqing Chao , Amit Dhurandhar , Pin-Yu Chen , Ali Tajer , Yangyang Xu , Pingkun Yan

In the problem of domain generalization (DG), there are labeled training data sets from several related prediction problems, and the goal is to make accurate predictions on future unlabeled data sets that are not known to the learner. This…

Machine Learning · Statistics 2021-01-08 Gilles Blanchard , Aniket Anand Deshmukh , Urun Dogan , Gyemin Lee , Clayton Scott

Domain generalization (DG) aims to learn from multiple known source domains a model that can generalize well to unknown target domains. The existing DG methods usually exploit the fusion of shared multi-source data to train a generalizable…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Junkun Yuan , Xu Ma , Defang Chen , Fei Wu , Lanfen Lin , Kun Kuang

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

Ki67 is a significant biomarker in the diagnosis and prognosis of cancer, whose index can be evaluated by quantifying its expression in Ki67 immunohistochemistry (IHC) stained images. However, quantitative analysis on multi-source Ki67…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Jiatong Cai , Chenglu Zhu , Can Cui , Honglin Li , Tong Wu , Shichuan Zhang , Lin Yang

Generalization capabilities of learning-based medical image segmentation across domains are currently limited by the performance degradation caused by the domain shift, particularly for ultrasound (US) imaging. The quality of US images…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Yuan Bi , Zhongliang Jiang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab

Automatic segmentation of infection areas in computed tomography (CT) images has proven to be an effective diagnosis approach for COVID-19. However, due to the limited number of pixel-level annotated medical images, accurate segmentation…

Image and Video Processing · Electrical Eng. & Systems 2021-09-13 Han Chen , Yifan Jiang , Murray Loew , Hanseok Ko

Deep learning models trained on medical images from a source domain (e.g. imaging modality) often fail when deployed on images from a different target domain, despite imaging common anatomical structures. Deep unsupervised domain adaptation…

Image and Video Processing · Electrical Eng. & Systems 2019-08-14 Cheng Ouyang , Konstantinos Kamnitsas , Carlo Biffi , Jinming Duan , Daniel Rueckert

The objective of domain generalization (DG) is to enable models to be robust against domain shift. DG is crucial for deploying vision-language models (VLMs) in real-world applications, yet most existing methods rely on domain labels that…

Machine Learning · Computer Science 2026-02-02 Zhixing Li , Arsham Gholamzadeh Khoee , Yinan Yu