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Skin lesion segmentation plays a critical role in the early detection and accurate diagnosis of dermatological conditions. Denoising Diffusion Probabilistic Models (DDPMs) have recently gained attention for their exceptional…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Afshin Bozorgpour , Yousef Sadegheih , Amirhossein Kazerouni , Reza Azad , Dorit Merhof

Although supervised deep-learning has achieved promising performance in medical image segmentation, many methods cannot generalize well on unseen data, limiting their real-world applicability. To address this problem, we propose a deep…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Vertebral fractures are a consequence of osteoporosis, with significant health implications for affected patients. Unfortunately, grading their severity using CT exams is hard and subjective, motivating automated grading methods. However,…

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

3D molecule generation is crucial for drug discovery and material science, requiring models to process complex multi-modalities, including atom types, chemical bonds, and 3D coordinates. A key challenge is integrating these modalities of…

Machine Learning · Computer Science 2025-10-14 Yanchen Luo , Zhiyuan Liu , Yi Zhao , Sihang Li , Hengxing Cai , Kenji Kawaguchi , Tat-Seng Chua , Yang Zhang , Xiang Wang

Given the inherently costly and time-intensive nature of pixel-level annotation, the generation of synthetic datasets comprising sufficiently diverse synthetic images paired with ground-truth pixel-level annotations has garnered increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Haoyu Wang , Lei Zhang , Wenrui Liu , Dengyang Jiang , Wei Wei , Chen Ding

Medical image segmentation is crucial for computer-aided diagnosis, which necessitates understanding both coarse morphological and semantic structures, as well as carving fine boundaries. The morphological and semantic structures in medical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Siyuan Song , Guyue Hu , Chenglong Li , Dengdi Sun , Zhe Jin , Jin Tang

Current semantic segmentation models typically require a substantial amount of manually annotated data, a process that is both time-consuming and resource-intensive. Alternatively, leveraging advanced text-to-image models such as Midjourney…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Bo Gao , Jianhui Wang , Xinyuan Song , Yangfan He , Fangxu Xing , Tianyu Shi

Medical image segmentation is a challenging task, made more difficult by many datasets' limited size and annotations. Denoising diffusion probabilistic models (DDPM) have recently shown promise in modelling the distribution of natural…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Margherita Rosnati , Melanie Roschewitz , Ben Glocker

Medical image segmentation using deep learning (DL) has enabled the development of automated analysis pipelines for large-scale population studies. However, state-of-the-art DL methods are prone to hallucinations, which can result in…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Vincenzo Marcianò , Hava Chaptoukaev , Virginia Fernandez , M. Jorge Cardoso , Sébastien Ourselin , Michela Antonelli , Maria A. Zuluaga

In this study, we introduce a generative model that can synthesize a large number of radiographical image/label pairs, and thus is asymptotically favorable to downstream activities such as segmentation in bio-medical image analysis.…

Image and Video Processing · Electrical Eng. & Systems 2023-04-20 Pham Ngoc Huy , Tran Minh Quan

Latent diffusion models have emerged as the dominant framework for high-fidelity and efficient image generation, owing to their ability to learn diffusion processes in compact latent spaces. However, while previous research has focused…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Qifan Li , Xingyu Zhou , Jinhua Zhang , Weiyi You , Shuhang Gu

Spatio-temporal compression of videos, utilizing networks such as Variational Autoencoders (VAE), plays a crucial role in OpenAI's SORA and numerous other video generative models. For instance, many LLM-like video models learn the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Sijie Zhao , Yong Zhang , Xiaodong Cun , Shaoshu Yang , Muyao Niu , Xiaoyu Li , Wenbo Hu , Ying Shan

Limited-angle computed tomography (LACT) reconstruction is an inverse problem with severe ill-posedness arising from missing projection angles, and it is difficult to restore high-precision images without sufficient prior knowledge. In…

Image and Video Processing · Electrical Eng. & Systems 2026-03-06 Hinako Isogai , Naruki Murahashi , Mitsuhiro Nakamura , Megumi Nakao

In medical imaging, segmentation models have known a significant improvement in the past decade and are now used daily in clinical practice. However, similar to classification models, segmentation models are affected by adversarial attacks.…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Othmane Laousy , Alexandre Araujo , Guillaume Chassagnon , Nikos Paragios , Marie-Pierre Revel , Maria Vakalopoulou

Deep learning has gained significant attention in medical image segmentation. However, the limited availability of annotated training data presents a challenge to achieving accurate results. In efforts to overcome this challenge, data…

Image and Video Processing · Electrical Eng. & Systems 2024-08-16 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Equivocal 3D lesion segmentation exhibits high inter-observer variability. Conventional deterministic models ignore this aleatoric uncertainty, producing over-confident masks that obscure clinical risks. Conversely, while generative methods…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Chao Wu , Kangxian Xie , Mingchen Gao

Sparse-view sampling in dual-energy computed tomography (DECT) significantly reduces radiation dose and increases imaging speed, yet is highly prone to artifacts. Although diffusion models have demonstrated potential in effectively handling…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Zini Chen , Yao Xiao , Junyan Zhang , Shaoyu Wang , Liu Shi , Qiegen Liu

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Skin lesion classification datasets often suffer from severe class imbalance, with malignant cases significantly underrepresented, leading to biased decision boundaries during deep learning training. We address this challenge using…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Francisco Filho , Kelvin Cunha , Fábio Papais , Emanoel dos Santos , Rodrigo Mota , Thales Bezerra , Erico Medeiros , Paulo Borba , Tsang Ing Ren